Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production (Q73721670)

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scientific article published on 01 January 2000

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English	Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production	scientific article published on 01 January 2000

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291028%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Overexpression of bcl-2 inhibits sodium butyrate-induced apoptosis in Chinese hamster ovary cells resulting in enhanced humanized antibody production (English)

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Europe PubMed Central

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6 November 2019

author name string

N S Kim

1

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6 November 2019

G M Lee

2

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6 November 2019

publication date

1 January 2000

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6 November 2019

Biotechnology and Bioengineering

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6 November 2019

71

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6 November 2019

3

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6 November 2019

184-193

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6 November 2019

Specific monoclonal antibody productivity and the cell cycle-comparisons of batch, continuous and perfusion cultures

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Death mechanisms of animal cells in conditions of intensive agitation

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Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line

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N-acetylcysteine increases the biosynthesis of recombinant EPO in apoptotic Chinese hamster ovary cells

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A protein phosphatase is involved in the inhibition of histone deacetylation by sodium butyrate

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21 January 2018

A novel cytostatic process enhances the productivity of Chinese hamster ovary cells

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Modulation of heat-shock protein 70 (HSP70) gene expression by sodium butyrate in U-937 promonocytic cells: relationships with differentiation and apoptosis

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Expression of recombinant plasmids in mammalian cells is enhanced by sodium butyrate

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21 January 2018

Apoptosis in batch cultures of Chinese hamster ovary cells

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21 January 2018

Mitochondria and apoptosis

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Foreign gene expression (beta-galactosidase) during the cell cycle phases in recombinant CHO cells

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Bcl-2 slows in vitro breast cancer growth despite its antiapoptotic effect

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21 January 2018

Na-butyrate increases the production and alpha2,6-sialylation of recombinant interferon-gamma expressed by alpha2,6- sialyltransferase engineered CHO cells

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21 January 2018

High-Level Expression of Human Inducible Nitric Oxide Synthase in Chinese Hamster Ovary Cells and Characterization of the Purified Enzyme

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21 January 2018

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

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21 January 2018

Bcl-2 deregulation leads to inhibition of sodium butyrate-induced apoptosis in human colorectal carcinoma cells.

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21 January 2018

Apoptosis-resistant E1B-19K-expressing NS/0 myeloma cells exhibit increased viability and chimeric antibody productivity under perfusion culture conditions.

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21 January 2018

bcl-2 expression in Spodoptera Frugiperda Sf-9 and Trichoplusia Ni BTI-Tn-5B1-4 insect cells: effect on recombinant protein expression and cell viability

1 reference

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21 January 2018

Effects of temperature shift on cell cycle, apoptosis and nucleotide pools in CHO cell batch cultues

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21 January 2018

Induction of recombinant human gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO Chinese hamster cells.

1 reference

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21 January 2018

Production of analytical quantities of recombinant proteins in Chinese hamster ovary cells using sodium butyrate to elevate gene expression

1 reference

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21 January 2018

Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells

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21 January 2018

Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells

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21 January 2018

Prevention of hybridoma cell death by bcl-2 during suboptimal culture conditions

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21 January 2018

Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells

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21 January 2018

n-Butyrate alters chromatin accessibility to DNA repair enzymes

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21 January 2018

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21 January 2018

Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.

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21 January 2018

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21 January 2018

Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21WAF/CIP1 in p53-independent manner

1 reference

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21 January 2018

Identifiers

10.1002/1097-0290(2000)71:3<184::AID-BIT1008>3.0.CO;2-W

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291028%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291028%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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