Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly (Q73996193)

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scientific article published on 01 January 1998

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English	Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly	scientific article published on 01 January 1998

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8 November 2019

Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly (English)

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8 November 2019

cystic fibrosis

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Y Lu

1

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8 November 2019

X Xiong

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8 November 2019

A Helm

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8 November 2019

K Kimani

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8 November 2019

A Bragin

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8 November 2019

W R Skach

6

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1 January 1998

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8 November 2019

Journal of Biological Chemistry

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8 November 2019

273

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8 November 2019

1

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8 November 2019

568-576

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8 November 2019

Intracellular protein topogenesis

1 reference

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21 January 2018

Multiple mechanisms of protein insertion into and across membranes.

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Nascent prehormones are intermediates in the biosynthesis of authentic bovine pituitary growth hormone and prolactin

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Synchronised transmembrane insertion and glycosylation of a nascent membrane protein

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Coupled cell-free synthesis, segregation, and core glycosylation of a secretory protein

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The erythrocyte anion transport protein is contranslationally inserted into microsomes

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Biogenesis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an integral glycoprotein of the endoplasmic reticulum

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Biogenesis of Polytopic Membrane Proteins: Membrane Segments of P-glycoprotein Sequentially Translocate To Span the ER Membrane†

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21 January 2018

Structural requirements for membrane assembly of proteins spanning the membrane several times

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21 January 2018

Insertion of a multispanning membrane protein occurs sequentially and requires only one signal sequence

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21 January 2018

Multiple topogenic sequences in bovine opsin

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Bovine opsin has more than one signal sequence

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Expression of fusion proteins of the nicotinic acetylcholine receptor from mammalian muscle identifies the membrane-spanning regions in the alpha and delta subunits

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Topological determinants of internal transmembrane segments in P-glycoprotein sequences.

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21 January 2018

Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum

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21 January 2018

Distinct biogenesis mechanisms for the water channels MIWC and CHIP28 at the endoplasmic reticulum

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Cloning and membrane topology of a P type ATPase from Helicobacter pylori

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The Membrane Topology of the Rat Sarcoplasmic and Endoplasmic Reticulum Calcium ATPases by in Vitro Translation Scanning

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Signal recognition protein is required for the integration of acetylcholine receptor delta subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane

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21 January 2018

Molecular mechanism of membrane protein integration into the endoplasmic reticulum

1 reference

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21 January 2018

Biogenesis of Polytopic Membrane Proteins: Membrane Segments Assemble within Translocation Channels prior to Membrane Integration

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21 January 2018

lac permease of Escherichia coli: topology and sequence elements promoting membrane insertion

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21 January 2018

Membrane protein spanning segments as export signals

1 reference

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21 January 2018

Determination of the transmembrane topology of yeast Sec61p, an essential component of the endoplasmic reticulum translocation complex

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21 January 2018

The human glucose transporter can insert posttranslationally into microsomes

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21 January 2018

Membrane integration of in vitro-translated gap junctional proteins: co- and post-translational mechanisms

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21 January 2018

Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator

1 reference

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21 January 2018

A Multifunctional Aqueous Channel Formed by CFTR

1 reference

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21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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21 January 2018

SecY, a multispanning integral membrane protein, contains a potential leader peptidase cleavage site

1 reference

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21 January 2018

Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia

1 reference

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21 January 2018

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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21 January 2018

Topology of eukaryotic type II membrane proteins: importance of N-terminal positively charged residues flanking the hydrophobic domain

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21 January 2018

NH2-terminal substitutions of basic amino acids induce translocation across the microsomal membrane and glycosylation of rabbit cytochrome P450IIC2.

1 reference

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21 January 2018

Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptide

1 reference

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21 January 2018

Predicting the orientation of eukaryotic membrane-spanning proteins

1 reference

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21 January 2018

Topogenic signals in integral membrane proteins

1 reference

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21 January 2018

The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment

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21 January 2018

Protein folding in the cell

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Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells

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Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

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The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process

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Approaching the mechanism of protein transport across the ER membrane.

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Discrete cross-linking products identified during membrane protein biosynthesis

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Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein

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Requirement of GTP Hydrolysis for Dissociation of the Signal Recognition Particle from Its Receptor

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A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane

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Bidirectional movement of a nascent polypeptide across microsomal membranes reveals requirements for vectorial translocation of proteins

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Membrane protein association by potential intrarnembrane charge pairs

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Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

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Electrostatic interactions of S4 voltage sensor in shaker K+ channel

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Molecular basis of charge movement in voltage-gated sodium channels

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S4 mutations alter gating currents of Shaker K channels

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

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Degradation of CFTR by the ubiquitin-proteasome pathway

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Identifiers

10.1074/JBC.273.1.568

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9417117%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9417117%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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