CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells (Q81391451)

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scientific article published on 01 October 2007

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English	CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells	scientific article published on 01 October 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913905%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913905%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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Eugene D Ponomarev

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913905%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Katarzyna Maresz

2

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Katarzyna Maresz

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8 January 2020

author name string

Yanping Tan

3

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8 January 2020

Bonnie N Dittel

4

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8 January 2020

publication date

1 October 2007

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8 January 2020

Journal of Neuroscience

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8 January 2020

27

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8 January 2020

40

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8 January 2020

10714-10721

1 reference

Europe PubMed Central

PMC publication ID

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8 January 2020

Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for Fas-dependent and Fas-independent mechanisms in the pathogenesis of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A macrophage protein, Ym1, transiently expressed during inflammation is a novel mammalian lectin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the Ym2 lectin-binding protein is dependent on interleukin (IL)-4 and IL-13 signal transduction: identification of a novel allergy-associated protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of nitric oxide synthase initiates relapsing remitting experimental autoimmune encephalomyelitis in rats, yet nitric oxide appears to be essential for clinical expression of disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 and interleukin-10 modulate nuclear factor kappaB activity and nitric oxide synthase-2 expression in Theiler's virus-infected brain astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia as liaisons between the immune and central nervous systems: functional implications for multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia in diseases of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mast Cells Exert Effects Outside the Central Nervous System to Influence Experimental Allergic Encephalomyelitis Disease Course

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular expression of murine Ym1 and Ym2, chitinase family proteins, as revealed by in situ hybridization and immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma delta T cell regulation of IFN-gamma production by central nervous system-infiltrating encephalitogenic T cells: correlation with recovery from experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma delta T cells regulate the extent and duration of inflammation in the central nervous system by a Fas ligand-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a culture system that supports adult microglial cell proliferation and maintenance in the resting state

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial cell activation and proliferation precedes the onset of CNS autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between microglia and oligodendrocyte cell progenitors involves Golli proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human and mouse microglia express connexin36, and functional gap junctions are formed between rodent microglia and neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and functional characterization of three activated macrophage populations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced cell-to-cell contacts between activated microglia and pyramidal cell dendrites following kainic acid-induced neurotoxicity in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the inducible isoform of nitric oxide synthase in the central nervous system of mice correlates with the severity of actively induced experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The multiplex function of nitric oxide in (auto)immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system delivery of interleukin 4 by a nonreplicative herpes simplex type 1 viral vector ameliorates autoimmune demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/17913905

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1922-07.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913905%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913905%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17913905%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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