Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion (Q90114682)

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scientific article published on 06 March 2020

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English	Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion	scientific article published on 06 March 2020

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11 April 2020

Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion (English)

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11 April 2020

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11 April 2020

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11 April 2020

Claudia Hube-Magg

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11 April 2020

Franziska Büscheck

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11 April 2020

Christina Möller-Koop

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11 April 2020

Doris Höflmayer

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Doris Höflmayer

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11 April 2020

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Hans Heinzer

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11 April 2020

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Sarah Minner

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11 April 2020

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Guido Sauter

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11 April 2020

Thorsten Schlomm

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Thorsten Schlomm

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11 April 2020

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Stefan Steurer

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11 April 2020

Till Sebastian Clauditz

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Till S Clauditz

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Eike Burandt

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11 April 2020

Christoph Fraune

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Christoph Fraune

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11 April 2020

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Luisa Harms

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11 April 2020

Maria Christina Tsourlakis

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Maria Christina Tsourlakis

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11 April 2020

Katharina Möller

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Katharina Möller

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11 April 2020

Sören A Weidemann

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Sören Weidemann

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11 April 2020

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Patrick Lebok

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11 April 2020

Jakob R Izbicki

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Jakob R Izbicki

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11 April 2020

author name string

Andreas M Luebke

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11 April 2020

David Dum

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11 April 2020

Simon Kind

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11 April 2020

Alexander Haese

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11 April 2020

Markus Graefen

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11 April 2020

Cornelia Schroeder

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11 April 2020

publication date

6 March 2020

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11 April 2020

Molecular Medicine

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11 April 2020

26

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11 April 2020

1

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11 April 2020

24

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11 April 2020

Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative analysis of AP-2 alpha and AP-2 beta gene expression during murine embryogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue microarrays for high-throughput molecular profiling of tumor specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-throughput tissue microarray analysis to evaluate genes uncovered by cDNA microarray screening in renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of activator protein 2 in prostate cancer is related to tumor differentiation and cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detecting activation of ribosomal protein S6 kinase by complementary DNA and tissue microarray analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of a novel human transcription factor AP-2 beta like gene (TFAP2BL1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activator protein 2alpha transcription factor expression is associated with luminal differentiation and is lost in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor gene AP-2 gamma essential for early murine development

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Tfap2d, the gene encoding the transcription factor Ap-2δ, during mouse embryogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of HER2 and its association with AP-2 in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual role of AP-2? in ErbB-2-induced mammary tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue microarrays for comparing molecular features with proliferation activity in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AP-2 family of transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genes differentially regulated by transcription factor, AP-2delta

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the TMPRSS2-ERG gene fusion in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of p53 alterations in surgically treated prostate cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of AR/TMPRSS2-ERG/Wnt signaling networks attenuates the aggressive behavior of prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upgrading and downgrading of prostate cancer from biopsy to radical prostatectomy: incidence and predictive factors using the modified Gleason grading system and factoring in tertiary grades

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG fusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of different types of p53 gene alteration in surgically treated prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concurrent deletion of 16q23 and PTEN is an independent prognostic feature in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-Level HOOK3 Expression Is an Independent Predictor of Poor Prognosis Associated with Genomic Instability in Prostate Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced AZGP1 expression is an independent predictor of early PSA recurrence and associated with ERG-fusion positive and PTEN deleted prostate cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical Utility of Quantitative Gleason Grading in Prostate Biopsies and Prostatectomy Specimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p16 upregulation is linked to poor prognosis in ERG negative prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of 18q is a strong and independent prognostic feature in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of 8p is an independent prognostic parameter in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up regulation and nuclear translocation of Y-box binding protein 1 (YB-1) is linked to poor prognosis in ERG-negative prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GeneHancer: genome-wide integration of enhancers and target genes in GeneCards

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High BCAR1 expression is associated with early PSA recurrence in ERG negative prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

13q deletion is linked to an adverse phenotype and poor prognosis in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

1 reference

https://pubmed.ncbi.nlm.nih.gov/32143573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/S10020-020-00148-4

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11 April 2020

PMC publication ID

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11 April 2020

PubMed publication ID

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11 April 2020

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