Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities (Q91774051)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

title

Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1

1 reference

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24 April 2020

Thomas O Auer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Filippo Del Bene

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

author name string

Jeffrey M Hubbard

2

1 reference

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24 April 2020

Kevin Fidelin

3

1 reference

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24 April 2020

Karine Duroure

4

1 reference

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24 April 2020

Céline Revenu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Claire Wyart

7

1 reference

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24 April 2020

publication date

10 July 2019

1 reference

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Molecular Neurodegeneration

24 April 2020

published in

1 reference

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24 April 2020

volume

14

1 reference

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24 April 2020

issue

1

1 reference

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24 April 2020

page(s)

27

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describes a project that uses

24 April 2020

NeuronJ

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6617949/fullTextXML

24 May 2022

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6617949/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Genetic compensation triggered by mutant mRNA degradation

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Targeted Genetic Screen in Amyotrophic Lateral Sclerosis Reveals Novel Genetic Variants with Synergistic Effect on Clinical Phenotype

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Using Touch-evoked Response and Locomotion Assays to Assess Muscle Performance and Function in Zebrafish

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Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility

23 February 2021

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How dynein and dynactin transport cargos: a structural perspective

23 February 2021

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A comprehensive review of amyotrophic lateral sclerosis

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TIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidance

23 February 2021

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The Synaptic Vesicle Release Machinery

23 February 2021

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Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3.

23 February 2021

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Exome sequencing uncovers hidden pathways in familial and sporadic ALS.

23 February 2021

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Structural organization of the dynein-dynactin complex bound to microtubules

23 February 2021

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ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease

23 February 2021

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Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration

23 February 2021

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Quantitative cell polarity imaging defines leader-to-follower transitions during collective migration and the key role of microtubule-dependent adherens junction formation

23 February 2021

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Recent progress in the genetics of motor neuron disease

23 February 2021

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Dynactin Deficiency in the CNS of Humans with Sporadic ALS and Mice with Genetically Determined Motor Neuron Degeneration

23 February 2021

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Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport

23 February 2021

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Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor

23 February 2021

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Control of muscle fibre-type diversity during embryonic development: the zebrafish paradigm

23 February 2021

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Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

23 February 2021

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Normal dynactin complex function during synapse growth in Drosophila requires membrane binding by Arfaptin

23 February 2021

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TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update

23 February 2021

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Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration

23 February 2021

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Axonal transport deficits and neurodegenerative diseases

23 February 2021

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The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian syndromes

23 February 2021

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Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

23 February 2021

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Evidence for an oligogenic basis of amyotrophic lateral sclerosis

23 February 2021

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Relay of retrograde synaptogenic signals through axonal transport of BMP receptors.

23 February 2021

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The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini

23 February 2021

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Dynactin is required for transport initiation from the distal axon

23 February 2021

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Molecular motor proteins and amyotrophic lateral sclerosis

23 February 2021

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Neuropathology and omics in motor neuron diseases

23 February 2021

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Generation of Rab-based transgenic lines for in vivo studies of endosome biology in zebrafish

23 February 2021

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FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

23 February 2021

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In vivo labeling of zebrafish motor neurons using an mnx1 enhancer and Gal4/UAS.

23 February 2021

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23 February 2021

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Retrograde axonal transport: pathways to cell death?

23 February 2021

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23 February 2021

Motor axon pathfinding

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Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

23 February 2021

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Regulators of the cytoplasmic dynein motor

23 February 2021

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Characterization of DCTN1 genetic variability in neurodegeneration.

23 February 2021

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Globally optimal stitching of tiled 3D microscopic image acquisitions

23 February 2021

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Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK receptor

23 February 2021

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Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient

23 February 2021

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The G59S mutation in p150(glued) causes dysfunction of dynactin in mice

23 February 2021

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The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs

23 February 2021

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23 February 2021

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Slit1a inhibits retinal ganglion cell arborization and synaptogenesis via Robo2-dependent and -independent pathways

23 February 2021

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Validation of zebrafish (Danio rerio) reference genes for quantitative real-time RT-PCR normalization.

23 February 2021

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Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment

23 February 2021

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The genetics of axonal transport and axonal transport disorders

23 February 2021

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Axonal transport and neurodegenerative disease

23 February 2021

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Axonal transport of microtubules: the long and short of it.

23 February 2021

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Evidence from in vivo imaging that synaptogenesis guides the growth and branching of axonal arbors by two distinct mechanisms.

23 February 2021

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A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation

23 February 2021

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In vivo imaging of preferential motor axon outgrowth to and synaptogenesis at prepatterned acetylcholine receptor clusters in embryonic zebrafish skeletal muscle.

23 February 2021

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Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.

23 February 2021

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Neuromuscular synapses can form in vivo by incorporation of initially aneural postsynaptic specializations

23 February 2021

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Paired motor neuron-muscle recordings in zebrafish test the receptor blockade model for shaping synaptic current.

23 February 2021

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Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

23 February 2021

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Neurotrophic regulation of the development and function of the neuromuscular synapses.

23 February 2021

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Mutant dynactin in motor neuron disease.

23 February 2021

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A role for regulated binding of p150(Glued) to microtubule plus ends in organelle transport

23 February 2021

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Dynactin is necessary for synapse stabilization.

23 February 2021

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

23 February 2021

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A mutation of early photoreceptor development, mikre oko, reveals cell-cell interactions involved in the survival and differentiation of zebrafish photoreceptors.

23 February 2021

1 reference

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Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction

23 February 2021

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Development of the vertebrate neuromuscular junction

23 February 2021

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The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport

23 February 2021

1 reference

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Mutations affecting development of the zebrafish retina

23 February 2021

1 reference

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Functionally distinct isoforms of dynactin are expressed in human neurons

23 February 2021

1 reference

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Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6617949

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6617949

Development and axonal outgrowth of identified motoneurons in the zebrafish

23 February 2021

1 reference

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Dynein is the motor for retrograde axonal transport of organelles

23 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6617949

10.1186/S13024-019-0327-3

23 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31291987%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

PubMed publication ID

31291987

1 reference