F3

F3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1AHW, 1BOY, 1DAN, 1FAK, 1J9C, 1JPS, 1O5D, 1TFH, 1UJ3, 1W0Y, 1W2K, 1WQV, 1WSS, 1WTG, 1WUN, 1WV7, 1Z6J, 2A2Q, 2AEI, 2AER, 2B7D, 2B8O, 2C4F, 2CEF, 2CEH, 2CEZ, 2CFJ, 2EC9, 2F9B, 2FIR, 2FLB, 2HFT, 2PUQ, 2ZP0, 2ZWL, 2ZZU, 3ELA, 3TH2, 3TH3, 3TH4, 4IBL, 4M7L, 4Z6A, 4ZMA, 4YLQ, 2FLR
Dynodwyr
Cyfenwau	F3, CD142, TF, TFA, coagulation factor III, tissue factor
Dynodwyr allanol	OMIM: 134390 HomoloGene: 1511 GeneCards: F3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0016518 cytokine receptor activity • phospholipid binding • serine-type endopeptidase activity • protease binding Cydrannau o'r gell • bilen • GO:0005578 extracellular matrix • intrinsic component of external side of plasma membrane • Cellbilen • extracellular region • extracellular exosome • cell surface • extracellular space • serine-type peptidase complex • integral component of membrane • collagen-containing extracellular matrix Prosesau biolegol • hemostasis • positive regulation of protein kinase B signaling • positive regulation of endothelial cell proliferation • cytokine-mediated signaling pathway • positive regulation of cell migration • activation of blood coagulation via clotting cascade • positive regulation of platelet-derived growth factor receptor signaling pathway • positive regulation of angiogenesis • blood coagulation, extrinsic pathway • activation of plasma proteins involved in acute inflammatory response • activation of cysteine-type endopeptidase activity involved in apoptotic process • positive regulation of positive chemotaxis • blood coagulation • protein processing Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2152	n/a
Ensembl	ENSG00000117525	n/a
UniProt	P13726	n/a
RefSeq (mRNA)	NM_001993 NM_001178096	n/a
RefSeq (protein)	NP_001171567 NP_001984	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn F3 yw F3 a elwir hefyd yn Coagulation factor III, tissue factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F3.

• TF
• TFA
• CD142

Llyfryddiaeth

• "Tissue Factor Expression Does Not Predict Mortality in Breast Cancer Patients. ". Anticancer Res. 2017. PMID 28551673.
• "Tissue factor levels in type 2 diabetes mellitus. ". Inflamm Res. 2017. PMID 28246677.
• "Platelet tissue factor activity and membrane cholesterol are increased in hypercholesterolemia and normalized by rosuvastatin, but not by atorvastatin. ". Atherosclerosis. 2017. PMID 28142075.
• "Tumor-Derived Tissue Factor Aberrantly Activates Complement and Facilitates Lung Tumor Progression via Recruitment of Myeloid-Derived Suppressor Cells. ". Int J Mol Sci. 2017. PMID 28106852.
• "The Neisseria meningitidis lpxL1 mutant induces less tissue factor expression and activity in primary human monocytes and monocyte-derived microvesicles than the wild type meningococcus.". Innate Immun. 2017. PMID 28024455.