A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein (Q22009982)

Calcium and integrin binding 1 (calmyrin)

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

S M Stabler

1

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L L Ostrowski

2

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S M Janicki

3

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M J Monteiro

Interaction of presenilins with the filamin family of actin-binding proteins

4

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language of work or name

English

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publication date

14 June 1999

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published in

Journal of Cell Biology

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volume

145

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issue

6

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page(s)

1277-92

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cites work

1 reference

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Interaction between DNA-dependent protein kinase and a novel protein, KIP

19 March 2017

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Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

19 March 2017

1 reference

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Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

19 March 2017

1 reference

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Presenilin 1 interaction in the brain with a novel member of the Armadillo family

19 March 2017

1 reference

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Molecular mechanics of calcium-myristoyl switches

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Sequestration of the membrane-targeting myristoyl group of recoverin in the calcium-free state

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Isolation of human delta-catenin and its binding specificity with presenilin 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Presenilin is required for activity and nuclear access of Notch in Drosophila

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

19 March 2017

https://api.crossref.org/works/10.1083/JCB.145.6.1277

The presenilin 2 loop domain interacts with the mu-calpain C-terminal region

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Direct association of presenilin-1 with beta-catenin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Presenilin mutations in Alzheimer's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Bleomycin hydrolase is associated with risk of sporadic Alzheimer's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

The role of calcium in the regulation of apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Alternative Cleavage of Alzheimer-Associated Presenilins During Apoptosis by a Caspase-3 Family Protease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Skeletal and CNS defects in Presenilin-1-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

The role of sequences unique to nuclear intermediate filaments in the targeting and assembly of human lamin B: evidence for lack of interaction of lamin B with its putative receptor.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I).

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Cell surface expression of the Alzheimer disease-related presenilin proteins

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Neurofilaments are obligate heteropolymers in vivo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Regulation of apoptosis by presenilin 1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Calcium binding, but not a calcium-myristoyl switch, controls the ability of guanylyl cyclase-activating protein GCAP-2 to regulate photoreceptor guanylyl cyclase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

The DNA-dependent protein kinase: a matter of life and (cell) death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Presenilins: genes for life and death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Amyloid, the presenilins and Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Determinants for intracellular sorting of cytoplasmic and nuclear intermediate filaments

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Characterization of Drosophila Presenilin and its colocalization with Notch during development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Calcineurin: not just a simple protein phosphatase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Neuronal localization of presenilin-1 and association with amyloid plaques and neurofibrillary tangles in Alzheimer's disease.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing

30 May 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Alpha-2 macroglobulin is genetically associated with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Calcium responses in fibroblasts from asymptomatic members of Alzheimer's disease families

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

The nuclear envelope lamina is reversibly depolymerized during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated tau by neuroleptics

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Integrin-mediated short-term memory in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Presenilins Are Processed by Caspase-type Proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Structure, expression profile, and chromosomal location of a mouse gene homologous to human DNA-PKcs interacting protein (KIP) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Regulation of brain G-protein go by Alzheimer's disease gene presenilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.145.6.1277

Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

Cytoskeletal changes in the brains of mice lacking calcineurin A alpha

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2133148

29 November 2018

Identifiers

DOI

10.1083/JCB.145.6.1277

1 reference

1 reference

1 reference

PubMed publication ID

10366599

1 reference