HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain (Q24318878)

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Language	Label	Description	Also known as
English	HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain	scientific article

Statements

scholarly article

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HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain (English)

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Huntingtin interacting protein 1

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GOA release 2020-03-11

structural constituent of cytoskeleton

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GOA release 2020-03-11

author name string

M A Kalchman

1

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H B Koide

2

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K McCutcheon

3

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R K Graham

4

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K Nichol

5

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K Nishiyama

6

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P Kazemi-Esfarjani

7

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F C Lynn

8

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C Wellington

9

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M Metzler

10

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Y P Goldberg

11

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I Kanazawa

12

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R D Gietz

13

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M R Hayden

14

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language of work or name

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publication date

May 1997

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Nature Genetics

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16

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1

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44-53

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Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

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A novel genetic system to detect protein-protein interactions

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Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

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A huntingtin-associated protein enriched in brain with implications for pathology

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end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae

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Two Ca2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences

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Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase

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HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

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When more is less: pathogenesis of glutamine repeat neurodegenerative diseases

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The expanding world of ataxins

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A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats

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CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

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Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype

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Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain

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Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

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Minireview. Emerging new functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells

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Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

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Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript

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Regional and cellular presenilin 1 gene expression in human and rat tissues

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Too close for comfort

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

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based on heuristic

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The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

1 reference

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Trinucleotide repeat length instability and age of onset in Huntington's disease

1 reference

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Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

1 reference

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Differential 3' polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression

1 reference

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Expression of the Huntington's disease (IT15) protein product in HD patients

1 reference

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Widespread expression of Huntington's disease gene (IT15) protein product

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Neuropathological classification of Huntington's disease

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Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

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Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent.

1 reference

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The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

1 reference

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Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae

1 reference

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MOP2(SLA2) Affects the Abundance of the Plasma Membrane H+-ATPase ofSaccharomyces cerevisiae

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Troponin T is capable of binding dystrophin via a leucine zipper

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Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

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Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells

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TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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Amino-acid sequence of the catalytic subunit of the (Na+ + K+)ATPase deduced from a complementary DNA.

1 reference

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Expression of normal and mutant huntingtin in the developing brain

1 reference

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inferred from DOI database lookup

Huntington disease: new insights into the relationship between CAG expansion and disease

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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10.1038/NG0597-44

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