TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response (Q35387454)

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Language	Label	Description	Also known as
English	TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response	scientific article

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

title

TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

main subject

DNA damage

0 references

author name string

Gernot Neumayer

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

Minh Dang Nguyen

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

language of work or name

English

0 references

publication date

3 November 2014

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stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

published in

PLOS One

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

volume

9

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

issue

11

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

page(s)

e110994

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

copyright license

Creative Commons Attribution 4.0 International

start time

3 November 2014

1 reference

stated in

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

TPX2: of spindle assembly, DNA damage response, and cancer

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Overexpressed TPX2 causes ectopic formation of microtubular arrays in the nuclei of acentrosomal plant cells

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12 July 2018

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

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12 July 2018

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

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12 July 2018

Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation

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TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

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SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60

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Identification of a TPX2-like microtubule-associated protein in Drosophila

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Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer

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BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.

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12 July 2018

Chfr and RNF8 synergistically regulate ATM activation

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12 July 2018

Replication stress induces 53BP1-containing OPT domains in G1 cells

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12 July 2018

Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events

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Hallmarks of Cancer: The Next Generation

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12 July 2018

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

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12 July 2018

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

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12 July 2018

DNA damage signaling in response to double-strand breaks during mitosis

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12 July 2018

Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs

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12 July 2018

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair

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PubMed Central

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12 July 2018

Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response

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PubMed Central

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12 July 2018

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair

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PubMed Central

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12 July 2018

Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition

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PubMed Central

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12 July 2018

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

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PubMed Central

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12 July 2018

Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

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PubMed Central

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12 July 2018

Solving the RIDDLE of 53BP1 recruitment to sites of damage

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12 July 2018

Crosstalk between histone modifications during the DNA damage response.

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PubMed Central

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12 July 2018

CBP/p300-mediated acetylation of histone H3 on lysine 56

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PubMed Central

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12 July 2018

Inhibition of SUV39H1 methyltransferase activity by DBC1

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12 July 2018

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

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12 July 2018

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

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PubMed Central

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12 July 2018

PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint

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PubMed Central

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12 July 2018

Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A

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12 July 2018

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication

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12 July 2018

The DNA damage response pathways: at the crossroad of protein modifications

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PubMed Central

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12 July 2018

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

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12 July 2018

NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs

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PubMed Central

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12 July 2018

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals

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12 July 2018

SIRT1 regulates the function of the Nijmegen breakage syndrome protein

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12 July 2018

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

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12 July 2018

The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly

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12 July 2018

A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites.

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12 July 2018

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

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12 July 2018

The histone code at DNA breaks: a guide to repair?

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12 July 2018

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

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12 July 2018

Involvement of human MOF in ATM function

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12 July 2018

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

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12 July 2018

The mechanism of spindle assembly: functions of Ran and its target TPX2

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12 July 2018

DNA damage-induced activation of ATM and ATM-dependent signaling pathways

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12 July 2018

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

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12 July 2018

BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair

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12 July 2018

Interaction of histone acetylases and deacetylases in vivo

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12 July 2018

Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells

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PubMed Central

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12 July 2018

Human TPX2 is required for targeting Aurora-A kinase to the spindle

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PubMed Central

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12 July 2018

Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death

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12 July 2018

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

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12 July 2018

TPX2, A novel xenopus MAP involved in spindle pole organization

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12 July 2018

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

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PubMed Central

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12 July 2018

The Hallmarks of Cancer

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12 July 2018

Megabase chromatin domains involved in DNA double-strand breaks in vivo

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12 July 2018

Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein

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12 July 2018

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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PubMed Central

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12 July 2018

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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PubMed Central

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12 July 2018

Cell cycle. Some importin news about spindle assembly

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21 January 2018

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

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26 September 2018

Determinants for Aurora-A activation and Aurora-B discrimination by TPX2.

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PubMed Central

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26 September 2018

Identifiers

DOI

10.1371/JOURNAL.PONE.0110994

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

ADS bibcode

2014PLoSO...9k0994N

0 references

PMC publication ID

4217740

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

PubMed publication ID

25365214

1 reference

stated in

Europe PubMed Central

PubMed publication ID

25365214

retrieved

8 August 2017

ResearchGate publication ID

267755154

0 references

 

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