PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 (Q24297155)

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English	PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1	scientific article

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

title

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 (English)

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

main subject

autophagy of mitochondrion

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GOA release 2020-03-11

author

Kira Holmström

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2

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

Fabienne C. Fiesel

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4

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

Wolfdieter Springer

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7

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

Philipp J Kahle

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6

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Philipp J Kahle

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Europe PubMed Central

PubMed publication ID

20098416

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17 January 2020

author name string

Sven Geisler

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1

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

Diana Skujat

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3

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

Oliver C Rothfuss

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5

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PubMed publication ID

20098416

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17 January 2020

language of work or name

English

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publication date

24 January 2010

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

published in

Nature Cell Biology

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

volume

12

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

issue

2

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

page(s)

119-131

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Europe PubMed Central

PubMed publication ID

20098416

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

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17 January 2020

cites work

PINK1 controls mitochondrial localization of Parkin through direct phosphorylation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways.

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PubMed

reference URL

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12 December 2020

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How does parkin ligate ubiquitin to Parkinson's disease?

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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The PINK1/Parkin pathway regulates mitochondrial morphology

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

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PubMed

reference URL

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12 December 2020

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The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins.

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12 December 2020

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Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

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PubMed

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12 December 2020

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

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PubMed

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12 December 2020

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12 December 2020

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Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

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PubMed

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12 December 2020

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Molecular interaction between parkin and PINK1 in mammalian neuronal cells

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12 December 2020

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Mitochondrial membrane permeabilization in cell death

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12 December 2020

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Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.

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PubMed

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12 December 2020

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Lysosomal localization of ubiquitinated Jun requires multiple determinants in a lysine-27-linked polyubiquitin conjugate

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PubMed

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12 December 2020

based on heuristic

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Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases?

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinase domain of mitochondrial PINK1 faces the cytoplasm

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin stabilizes PINK1 through direct interaction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lewy bodies

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-synuclein and neurodegenerative diseases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin recognition by the ubiquitin-associated domain of p62 involves a novel conformational switch

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20098416

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12 December 2020

based on heuristic

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Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

1 reference

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PubMed

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB2012

2 references

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5665

stated in

Europe PubMed Central

PubMed publication ID

20098416

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

retrieved

17 January 2020

Dimensions Publication ID

1021281910

0 references

OpenCitations bibliographic resource ID

5665

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5665

PubMed publication ID

20098416

2 references

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5665

stated in

Europe PubMed Central

PubMed publication ID

20098416

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20098416%20AND%20SRC:MED&resulttype=core&format=json

retrieved

17 January 2020

ResearchGate publication ID

41123797

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