mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module (Q24535019)

1

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S Khouangsathiene

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M S Kapiloff

3

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R Mouton

4

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E V Hill

5

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M D Houslay

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L K Langeberg

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J D Scott

Myomegalin is a novel protein of the golgi/centrosome that interacts with a cyclic nucleotide phosphodiesterase

8

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language of work or name

English

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publication date

17 April 2001

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published in

The EMBO Journal

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volume

20

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issue

8

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page(s)

1921-30

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cites work

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PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

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Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

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The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

24 March 2017

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A-kinase anchoring protein 100 (AKAP100) is localized in multiple subcellular compartments in the adult rat heart

24 March 2017

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A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events

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Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins

24 March 2017

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Voltage-dependent potentiation of L-type Ca2+ channels in skeletal muscle cells requires anchored cAMP-dependent protein kinase

24 March 2017

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Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain

24 March 2017

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Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

24 March 2017

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Signaling through scaffold, anchoring, and adaptor proteins

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ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions

24 March 2017

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The unique N-terminal domain of the cAMP phosphodiesterase PDE4D4 allows for interaction with specific SH3 domains

24 March 2017

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Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus

24 March 2017

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The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform

24 March 2017

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Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

24 March 2017

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AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes

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Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

24 March 2017

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Multiple cyclic nucleotide phosphodiesterases

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Signaling--2000 and beyond

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Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

7 April 2017

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7 April 2017

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Phosphodiesterases and cyclic nucleotide signaling in endocrine cells

27 September 2017

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Pericentrin anchors protein kinase A at the centrosome through a newly identified RII-binding domain

27 September 2017

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Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions

27 September 2017

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Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei

27 September 2017

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Activation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation. Identification and function of an inhibitory domain

27 September 2017

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AKAPs: from structure to function

27 September 2017

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27 September 2017

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Subcellular localization of rolipram-sensitive, cAMP-specific phosphodiesterases. Differential targeting and activation of the splicing variants derived from the PDE4D gene

27 September 2017

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cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model.

27 September 2017

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A-kinase anchor protein 75 increases the rate and magnitude of cAMP signaling to the nucleus

27 September 2017

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Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase

27 September 2017

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Short term feedback regulation of cAMP in FRTL-5 thyroid cells. Role of PDE4D3 phosphodiesterase activation.

27 September 2017

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The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions

30 May 2018

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Catecholamine-induced cardiac hypertrophy: significance of proto-oncogene expression

30 May 2018

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Preparation of homogeneous cyclic AMP-dependent protein kinase(s) and its subunits from rabbit skeletal muscle

30 May 2018

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UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions.

30 May 2018

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Altered Expression of PDE1 and PDE4 Cyclic Nucleotide Phosphodiesterase Isoforms in 7-oxo-prostacyclin-preconditioned Rat Heart

29 November 2018

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Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: changes in pulmonary hypertension

29 November 2018

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Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons

29 November 2018

1 reference

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Assay of cyclic AMP-dependent protein kinases

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1 reference

12 December 2020

Rolipram increases cyclic GMP content in L-arginine-treated cultured bovine aortic endothelial cells

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Compartmentalization of PDE-4 and cAMP-dependent protein kinase in neutrophils and macrophages during phagocytosis

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Cellular mechanisms of cardiac hypertrophy

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Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein kinases. A potential mechanism allowing for the coordinated regulation of

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12 December 2020

Identifiers

DOI

10.1093/EMBOJ/20.8.1921

1 reference

1 reference

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PubMed publication ID

11296225

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