Two distinct mechanisms for negative regulation of the Wee1 protein kinase (Q24564436)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

title

Two distinct mechanisms for negative regulation of the Wee1 protein kinase (English)

1 reference

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19 October 2019

author name string

Z Tang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

T R Coleman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

W G Dunphy

series ordinal

3

1 reference

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19 October 2019

language of work or name

English

0 references

publication date

1 September 1993

1 reference

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19 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

volume

12

1 reference

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19 October 2019

issue

9

1 reference

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19 October 2019

page(s)

3427-3436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

19 October 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Conservation of mitotic controls in fission and budding yeasts

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Universal control mechanism regulating onset of M-phase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Negative regulation of the weel protein kinase by direct action of the nim1/cdr1 mitotic inducer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Induction of nuclear envelope breakdown, chromosome condensation, and spindle formation in cell-free extracts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cyclin synthesis drives the early embryonic cell cycle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Driving the cell cycle: M phase kinase, its partners, and substrates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Genetic and molecular analysis of cdr1/nim1 in Schizosaccharomyces pombe

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

cdc2 phosphorylation is required for its interaction with cyclin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Activation of human cyclin-dependent kinases in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Role of phosphorylation in p34cdc2 activation: identification of an activating kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Genetic control of cell size at cell division in yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cyclin activation of p34cdc2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

INH, a negative regulator of MPF, is a form of protein phosphatase 2A

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Cloning and Characterization of Xenopus cdc2, a Component of MPF

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Fission yeast p107wee1 mitotic inhibitor is a tyrosine/serine kinase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

The cdc25 protein contains an intrinsic phosphatase activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Regulation of the cdc25 protein during the cell cycle in Xenopus extracts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Coupling of mitosis to the completion of S phase in Xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413619

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7504624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7504624

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/J.1460-2075.1993.TB06017.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

3205372

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3205372

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7504624%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

PubMed publication ID

7504624

2 references

Consolidated OpenCitations Corpus – April 2017

3205372