Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy (Q24646296)

Seminars in Cancer Biology

Europe PubMed Central

title

Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy (English)

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Saroj P Mathupala

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Young H Ko

series ordinal

2

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Peter L Pedersen

series ordinal

3

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language of work or name

English

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publication date

February 2009

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published in

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volume

19

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issue

1

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page(s)

17-24

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cites work

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12 December 2020

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12 December 2020

Evidence that transcription of the hexokinase gene is increased in a rapidly growing rat hepatoma

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Functional organization of mammalian hexokinases: characterization of the rat type III isozyme and its chimeric forms, constructed with the N- and C-terminal halves of the type I and type II isozymes

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Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells

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Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention

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12 December 2020

10.1016/J.SEMCANCER.2008.11.006

Identifiers

DOI

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PubMed publication ID

19101634

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