Recent Advances on Pathophysiology, Diagnostic and Therapeutic Insights in Cardiac Dysfunction Induced by Antineoplastic Drugs (Q28087776)

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Giancarlo Marone

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Mario Petretta

4

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Domenico Bonaduce

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Carlo Gabriele Tocchetti

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Marilisa Molinaro

1

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7 June 2020

Fabio Di Lisa

6

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7 June 2020

Sabino De Placido

7

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7 June 2020

Pasquale Abete

5

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7 June 2020

language of work or name

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2015

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BioMed Research International

25 October 2015

6 references

22 March 2019

3 April 2019

17 June 2019

14 September 2020

8 February 2021

1 May 2021

8 references

22 March 2019

3 April 2019

17 June 2019

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7 June 2020

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Rationale and design of the Multidisciplinary Approach to Novel Therapies in Cardiology Oncology Research Trial (MANTICORE 101--Breast): a randomized, placebo-controlled trial to determine if conventional heart failure pharmacotherapy can prevent tr

29 September 2017

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β2-adrenergic receptors mediate cardioprotection through crosstalk with mitochondrial cell death pathways

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology

29 September 2017

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Left ventricular dysfunction in patients receiving cardiotoxic cancer therapies are clinicians responding optimally?

29 September 2017

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Cardiotoxicity of anticancer treatments: what the cardiologist needs to know

29 September 2017

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29 September 2017

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29 September 2017

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Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase

29 September 2017

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29 September 2017

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Cancer treatment-induced cardiotoxicity: a cardiac stem cell disease?

29 September 2017

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Anthracycline-induced cardiomyopathy: clinical relevance and response to pharmacologic therapy.

29 September 2017

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Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress.

29 September 2017

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The vulnerability of the heart as a pluricellular paracrine organ: lessons from unexpected triggers of heart failure in targeted ErbB2 anticancer therapy

29 September 2017

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Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention

29 September 2017

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Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management

29 September 2017

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Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle

29 September 2017

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Role of carvedilol controlled-release in cardiovascular disease

29 September 2017

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Inhibition of ErbB2 by receptor tyrosine kinase inhibitors causes myofibrillar structural damage without cell death in adult rat cardiomyocytes

29 September 2017

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Intricacies of bevacizumab-induced toxicities and their management

29 September 2017

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Development of targeted angiogenic medicine.

29 September 2017

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Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate

29 September 2017

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Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation.

29 September 2017

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Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib

29 September 2017

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Molecular mechanisms of cardiotoxicity of tyrosine kinase inhibition

29 September 2017

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Congestive heart failure is a rare event in patients receiving imatinib therapy

29 September 2017

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Prevention of high-dose chemotherapy-induced cardiotoxicity in high-risk patients by angiotensin-converting enzyme inhibition

29 September 2017

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Chronic health conditions in adult survivors of childhood cancer

29 September 2017

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Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.

29 September 2017

1 reference

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Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Imaging cardiac neuronal function and dysfunction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Differential cardiotoxic/cardioprotective effects of beta-adrenergic receptor subtypes in myocytes and fibroblasts in doxorubicin cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.

29 September 2017

1 reference

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Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Prognostic value of troponin I in cardiac risk stratification of cancer patients undergoing high-dose chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

The imbalance between oxygen demand and supply as a potential mechanism in the pathophysiology of heart failure: the role of microvascular growth and abnormalities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Myocardial injury revealed by plasma troponin I in breast cancer treated with high-dose chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Cardiotoxicity of doxorubicin and other anthracycline derivatives

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Mitoxantrone: an active, new antitumor agent with an improved therapeutic index

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

5-Fluorouracil-associated cardiotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

The cardiotoxicity of chemotherapeutic drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Cardiotoxicity of high-dose continuous infusion fluorouracil: a prospective clinical study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Nitroso-Redox Balance and Modulation of Basal Myocardial Function: An Update from the Italian Society of Cardiovascular Research (SIRC).

29 September 2017

1 reference

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Subclinical anthracycline- and trastuzumab-induced cardiotoxicity in the long-term follow-up of asymptomatic breast cancer survivors: a speckle tracking echocardiographic study

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Cardiac growth and angiogenesis coordinated by intertissue interactions

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Exercise echocardiography reveals subclinical cardiac dysfunction in young adult survivors of childhood acute lymphoblastic leukemia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Protective effects of carvedilol against anthracycline-induced cardiomyopathy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Tissue Doppler imaging and conventional echocardiography after anthracycline treatment in adults: early and late alterations of left ventricular function during a prospective study.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Symptomatic cardiotoxicity associated with 5-fluorouracil

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Female sex and higher drug dose as risk factors for late cardiotoxic effects of doxorubicin therapy for childhood cancer.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

Myocardial 2D strain echocardiography and cardiac biomarkers in children during and shortly after anthracycline therapy for acute lymphoblastic leukaemia (ALL): a prospective study.

2 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Doxorubicin, cardiac risk factors, and cardiac toxicity in elderly patients with diffuse B-cell non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Doxorubicin induces senescence and impairs function of human cardiac progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Longitudinal changes in cardiac function after cisplatin-based chemotherapy for testicular cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Incidence of cardiotoxicity with the oral fluoropyrimidine capecitabine is typical of that reported with 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Capecitabine can induce acute coronary syndrome similar to 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

The atomic structure of Mengo virus at 3.0 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

ErbB2 is essential in the prevention of dilated cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Angiogenesis, lymphangiogenesis and clinical implications. Preface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

The lack of target specificity of small molecule anticancer kinase inhibitors is correlated with their ability to damage myocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Heart failure associated with sunitinib malate: a multitargeted receptor tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Sunitinib causes dose-dependent negative functional effects on myocardium and cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Cardiovascular toxicity following sunitinib therapy in metastatic renal cell carcinoma: a multicenter analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Incidence and risk of congestive heart failure in patients with renal and nonrenal cell carcinoma treated with sunitinib.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Treatment-emergent hypertension and outcomes in patients with advanced non-small-cell lung cancer receiving chemotherapy with or without the vascular endothelial growth factor receptor inhibitor cediranib: NCIC Clinical Trials Group Study BR24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Arterial hypertension correlates with clinical outcome in colorectal cancer patients treated with first-line bevacizumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

β-Adrenergic blockade for anthracycline- and trastuzumab-induced cardiotoxicity: is prevention better than cure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Role of three-dimensional echocardiography in breast cancer: comparison with two-dimensional echocardiography, multiple-gated acquisition scans, and cardiac magnetic resonance imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Utility of tissue Doppler and strain rate imaging in the early detection of trastuzumab and anthracycline mediated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Use of myocardial deformation imaging to detect preclinical myocardial dysfunction before conventional measures in patients undergoing breast cancer treatment with trastuzumab.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Assessment of systolic left ventricular function: a multi-centre comparison of cineventriculography, cardiac magnetic resonance imaging, unenhanced and contrast-enhanced echocardiography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography: a comparison with magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Clinical relevance of radionuclide angiography and antimyosin immunoscintigraphy for risk assessment in epirubicin cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

High sensitivity of radiolabelled antimyosin scintigraphy in assessing anthracycline related early myocyte damage preceding cardiac dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Elevated B-type natriuretic peptide levels after anthracycline administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Natriuretic peptides in the monitoring of anthracycline induced reduction in left ventricular ejection fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Usefulness of cardiac resynchronization therapy in patients with Adriamycin-induced cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies: the OVERCOME trial (preventiOn of left Ventricular dysfunction with Enalapril and caRvedilol in patients submi

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Effect of statin therapy on the risk for incident heart failure in patients with breast cancer receiving anthracycline chemotherapy: an observational clinical cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Cardioprotective effect of β-adrenoceptor blockade in patients with breast cancer undergoing chemotherapy: follow-up study of heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Protective effect of carvedilol on daunorubicin-induced cardiotoxicity and nephrotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Effect of telmisartan in limiting the cardiotoxic effect of daunorubicin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Beneficial effects of angiotensin II receptor blocker, olmesartan, in limiting the cardiotoxic effect of daunorubicin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Prominent cardioprotective effects of third generation beta blocker nebivolol against anthracycline-induced cardiotoxicity using the model of isolated perfused rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Creatine kinase-overexpression improves myocardial energetics, contractile dysfunction and survival in murine doxorubicin cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

Paving new paths for neuregulin-1-assisted cardiac regenerative medicine. Focus on “Improving murine embryonic stem cell differentiation into cardiomyocytes with neuregulin-1: differential expression of microRNA”

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2015%2F138148

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4637019

A comparison of cardiac biopsy grades and ejection fraction estimations in patients receiving Adriamycin

27 November 2018

1 reference

12 December 2020

Type II chemotherapy-related cardiac dysfunction: time to recognize a new entity

1 reference

12 December 2020

The utility of cardiac biomarkers, tissue velocity and strain imaging, and cardiac magnetic resonance imaging in predicting early left ventricular dysfunction in patients with human epidermal growth factor receptor II-positive breast cancer treated

1 reference

12 December 2020

Neuregulin-1 beta attenuates doxorubicin-induced alterations of excitation-contraction coupling and reduces oxidative stress in adult rat cardiomyocytes

1 reference

12 December 2020

Microvascular plasticity and experimental heart failure

1 reference

12 December 2020

Heat shock protein 90 and ErbB2 in the cardiac response to doxorubicin injury

1 reference

12 December 2020

[Evaluation in vitro of the cardiotoxic effects of 5-fluorouracil for the prevention of cardiovascular damage in health workers occupationally exposed]

1 reference

12 December 2020

Anthracycline-induced cardiotoxicity in children with malignancies

1 reference

12 December 2020

Doxorubicin cardiotoxicity in the elderly: old drugs and new opportunities

1 reference

12 December 2020

Reversibility of trastuzumab-related cardiotoxicity: new insights based on clinical course and response to medical treatment

1 reference

12 December 2020

Troponin I Provides Insight Into Cardiotoxicity and the Anthracycline-Trastuzumab Interaction

1 reference

12 December 2020

Trastuzumab and breast cancer

1 reference

12 December 2020

Efficiency of atorvastatin in the protection of anthracycline-induced cardiomyopathy

1 reference

12 December 2020

Anthracycline cardiotoxicity

1 reference

12 December 2020

Anthracyclines and heart failure

1 reference

12 December 2020

Cardiotoxicity of fluoropyrimidines in different schedules of administration: a prospective study

1 reference

12 December 2020

Left ventricular ejection fraction and cardiotoxicity: is our ear really to the ground?

1 reference

12 December 2020

Doxorubicin cardiotoxicity in children

1 reference

12 December 2020

Identifiers

DOI

10.1155/2015/138148

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26583088%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26583088%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

26583088

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26583088%20AND%20SRC:MED&resulttype=core&format=json