Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth (Q28211693)

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English	Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth	scientific article

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6 November 2019

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth (English)

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6 November 2019

Serine/threonine kinase 11

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GOA release 2020-03-11

phosphorylation

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based on heuristic

inferred from title

3

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6 November 2019

Simon J. Arthur

5

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9

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G P Sapkota

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A Kieloch

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S Lain

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M R Williams

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N Morrice

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M Deak

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31 January 2001

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6 November 2019

Journal of Biological Chemistry

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6 November 2019

276

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19469-19482

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6 November 2019

The molecular basis and clinical aspects of Peutz-Jeghers syndrome

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21 January 2018

Peutz-Jeghers syndrome: 78-year follow-up of the original family

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21 January 2018

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

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https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

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https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009953200

21 January 2018

The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase

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21 January 2018

Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos

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21 January 2018

LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo

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21 January 2018

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

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21 January 2018

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

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Ribosomal S6 kinase signaling and the control of translation

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Protein prenylation: molecular mechanisms and functional consequences

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Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

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The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

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MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells

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21 January 2018

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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21 January 2018

Molecular pharmacology of protein kinases

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21 January 2018

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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21 January 2018

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

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21 January 2018

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

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21 January 2018

The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase.

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Characterisation of a plant 3-phosphoinositide-dependent protein kinase-1 homologue which contains a pleckstrin homology domain

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21 January 2018

Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides

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21 January 2018

The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

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21 January 2018

Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

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21 January 2018

Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

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21 January 2018

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

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21 January 2018

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

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Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells

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21 January 2018

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity

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21 January 2018

Activation of the cyclic AMP cascade as an oncogenic mechanism: the thyroid example

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The cyclic AMP-mediated stimulation of cell proliferation

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Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle

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Serine/threonine protein kinases and apoptosis.

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Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

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BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

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14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

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[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

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10.1074/JBC.M009953200

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Consolidated OpenCitations Corpus – April 2017

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