Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair (Q28295270)

LIM and senescent cell antigen-like domains 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Integrin linked kinase

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GOA release 2020-03-11

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Ankur Saxena

2

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author name string

Ildiko Bock-Marquette

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Michael D White

3

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J Michael Dimaio

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Deepak Srivastava

Bone marrow cells regenerate infarcted myocardium

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language of work or name

English

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publication date

25 November 2004

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published in

Nature

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volume

432

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issue

7016

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page(s)

466-72

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cites work

1 reference

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

21 April 2017

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Biochemical and antibacterial analysis of human wound and blister fluid

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Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

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STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription

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Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 April 2017

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GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

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Adult cardiac stem cells are multipotent and support myocardial regeneration

21 April 2017

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The incidence of congenital heart disease

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Myocyte renewal and ventricular remodelling

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Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium

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Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

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A genetic blueprint for cardiac development

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beta-Thymosins, small acidic peptides with multiple functions

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The beta-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly

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The small GTP-binding protein RhoA regulates c-jun by a ROCK-JNK signaling axis.

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Nuclear actin and actin-related proteins in chromatin remodeling.

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Thymosin beta4 accelerates wound healing.

1 reference

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7 January 2021

Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury

1 reference

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7 January 2021

Thymosin beta4 enhances endothelial cell differentiation and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE03000

7 January 2021

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

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7 January 2021

Developmental expression of mRNAs encoding thymosins beta 4 and beta 10 in rat brain and other tissues

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7 January 2021

High levels of mouse thymosin beta4 mRNA in differentiating P19 embryonic cells and during development of cardiovascular tissues

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7 January 2021

Myocardialization of the cardiac outflow tract

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7 January 2021

The anterior heart-forming field: voyage to the arterial pole of the heart

1 reference

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7 January 2021

Bone marrow endothelial cells secrete thymosin beta4 and AcSDKP.

1 reference

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7 January 2021

Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue

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7 January 2021

PKB binding proteins. Getting in on the Akt.

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Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts

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7 January 2021

Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice

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Program of cell survival underlying human and experimental hibernating myocardium

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Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer

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7 January 2021

Macrophage migration inhibitory factor is a cardiac-derived myocardial depressant factor

1 reference

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7 January 2021

Biodistribution of synthetic thymosin beta 4 in the serum, urine, and major organs of mice

1 reference

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7 January 2021