Integrin linked kinase (Q21495079)

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mammalian protein found in Mus musculus
  • integrin binding protein kinase
  • 59 kDa serine/threonine-protein kinase
  • integrin-linked protein kinase
  • Ilk
  • beta-integrin-linked kinase
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Language Label Description Also known as
English
Integrin linked kinase
mammalian protein found in Mus musculus
  • integrin binding protein kinase
  • 59 kDa serine/threonine-protein kinase
  • integrin-linked protein kinase
  • Ilk
  • beta-integrin-linked kinase

Statements

molecular function
protein binding
determination method or standard
IPI
8 references
retrieved
14 February 2019
stated in
Interaction of bcl-2 with Paxillin through its BH4 domain is important during ureteric bud branching
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
retrieved
14 February 2019
stated in
Integrin-linked kinase is an adaptor with essential functions during mouse development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IPI
cell component
focal adhesion
determination method or standard
IDA
IEA
ISO
6 references
retrieved
21 June 2018
stated in
Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222
determination method or standard
ISO
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O55222
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222
determination method or standard
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222
determination method or standard
IEA
retrieved
21 June 2018
stated in
Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222
determination method or standard
IDA
retrieved
21 June 2018
stated in
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222
determination method or standard
IDA
retrieved
21 June 2018
stated in
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O55222&geneProductId=UniProtKB:O55222
determination method or standard
IDA
focal adhesion
determination method or standard
IBA
IDA
IEA
ISO
7 references
retrieved
14 February 2019
stated in
Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
ISO
retrieved
14 February 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O55222
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IEA
retrieved
14 February 2019
stated in
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IDA
retrieved
14 February 2019
stated in
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IDA
retrieved
14 February 2019
stated in
Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O55222
determination method or standard
IBA
biological process

Identifiers

 
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