Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts (Q28504667)

24 January 2017

title

Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts (English)

1 reference

Beta-site APP cleaving enzyme 1

24 January 2017

1 reference

1 reference

GOA release 2020-03-11

1 reference

Masaki Fukata

8

0 references

Nabil Seidah

5

object named as

Nabil G. Seidah

1 reference

24 January 2017

author name string

Kulandaivelu S. Vetrivel

1

1 reference

24 January 2017

Xavier Meckler

2

1 reference

24 January 2017

Ying Chen

3

1 reference

24 January 2017

Phuong D. Nguyen

4

1 reference

24 January 2017

Robert Vassar

6

1 reference

24 January 2017

Philip C. Wong

7

1 reference

24 January 2017

Maria Z. Kounnas

9

1 reference

24 January 2017

Gopal Thinakaran

10

1 reference

24 January 2017

language of work or name

English

0 references

publication date

6 February 2009

1 reference

Journal of Biological Chemistry

24 January 2017

published in

1 reference

24 January 2017

volume

284

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24 January 2017

issue

6

1 reference

24 January 2017

page(s)

3793–3803

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Palmitoylation: policing protein stability and traffic

24 January 2017

cites work

1 reference

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19 March 2017

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19 March 2017

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7 April 2017

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29 September 2017

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Palmitoylation controls recycling in lysosomal sorting and trafficking

29 September 2017

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PCSK9 is required for the disposal of non-acetylated intermediates of the nascent membrane protein BACE1.

29 September 2017

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The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology

29 September 2017

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Lovastatin inhibits amyloid precursor protein (APP) beta-cleavage through reduction of APP distribution in Lubrol WX extractable low density lipid rafts

29 September 2017

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Mechanisms of disease: new therapeutic strategies for Alzheimer's disease--targeting APP processing in lipid rafts

29 September 2017

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Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635050

Lipid rafts, detergent-resistant membranes, and raft targeting signals

29 September 2017

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Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol.

29 September 2017

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29 September 2017

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29 September 2017

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Lovastatin stimulates up-regulation of alpha7 nicotinic receptors in cultured neurons without cholesterol dependency, a mechanism involving production of the alpha-form of secreted amyloid precursor protein.

29 September 2017

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Modulation of neuronal protein trafficking and function by palmitoylation

29 September 2017

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BACE is degraded via the lysosomal pathway

29 September 2017

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GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network

29 September 2017

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beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

29 September 2017

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BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo

29 September 2017

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The gamma-secretase complex: machinery for intramembrane proteolysis

29 September 2017

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Effects of cholesterol depletion and increased lipid unsaturation on the properties of endocytic membranes.

29 September 2017

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Lipid rafts: elusive or illusive?

29 September 2017

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The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

29 September 2017

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Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

29 September 2017

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Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

29 September 2017

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Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

29 September 2017

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Phosphorylation regulates intracellular trafficking of beta-secretase

29 September 2017

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

29 September 2017

1 reference

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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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2 June 2018

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21 January 2018

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21 January 2018

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