Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis (Q28589373)

31 January 2017

title

Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis (English)

1 reference

Advanced glycosylation end product-specific receptor

31 January 2017

main subject

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S100 calcium binding protein A8 (calgranulin A)

1 reference

S100 calcium binding protein A9 (calgranulin B)

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Kirsten rat sarcoma viral oncogene homolog

1 reference

Toll-like receptor 4

1 reference

1 reference

Hongda Li

7

0 references

author name string

Myung-Jeom Ryu

1

1 reference

31 January 2017

Yangang Liu

2

1 reference

31 January 2017

Xiaofen Zhong

3

1 reference

31 January 2017

Juan Du

4

1 reference

31 January 2017

Nicholas Peterson

5

1 reference

31 January 2017

Guangyao Kong

6

1 reference

31 January 2017

Jinyong Wang

8

1 reference

31 January 2017

Shahriar Salamat

9

1 reference

31 January 2017

Qiang Chang

10

1 reference

31 January 2017

Jing Zhang

11

1 reference

31 January 2017

language of work or name

English

0 references

publication date

29 June 2012

1 reference

Journal of Biological Chemistry

31 January 2017

published in

1 reference

31 January 2017

volume

287

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31 January 2017

issue

27

1 reference

31 January 2017

page(s)

22948–22958

1 reference

describes a project that uses

31 January 2017

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3391097/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

S100A8 and S100A9 activate MAP kinase and NF-kappaB signaling pathways and trigger translocation of RAGE in human prostate cancer cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

DAVID: Database for Annotation, Visualization, and Integrated Discovery

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

The neurofibromatosis type 1 gene encodes a protein related to GAP

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Isolation of brain and spinal cord mononuclear cells using percoll gradients

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

S100A8/A9 activate key genes and pathways in colon tumor progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

S100A8/A9: a Janus-faced molecule in cancer therapy and tumorgenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

EDGE(3): a web-based solution for management and analysis of Agilent two color microarray experiments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Using neurofibromatosis-1 to better understand and treat pediatric low-grade glioma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Isolation of murine microglial cells for RNA analysis or flow cytometry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

S100A8 and S100A9 in inflammation and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Microglia function in brain tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Myeloid cell function in MRP-14 (S100A9) null mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Spreading depression increases immunohistochemical staining of glial fibrillary acidic protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Neuronal activity up-regulates astroglial gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Reactive astrocytes: cellular and molecular cues to biological function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Neurofibromin Expression and Astrogliosis in Neurofibromatosis (Type 1) Brains

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Loss of neurofibromin is associated with activation of RAS/MAPK and PI3-K/AKT signaling in a neurofibromatosis 1 astrocytoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Proteomic analysis of gamma-butyrolactone-treated mouse thalamus reveals dysregulated proteins upon absence seizure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Extracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Chemotactic activity of S100A8 and S100A9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.357772

Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3391097

Identification of a chemotactic domain of the pro-inflammatory S100 protein CP-10

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22577135

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Acute inflammatory activity of the S100 protein CP-10. Activation of neutrophils in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22577135

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.357772

1 reference

31 January 2017

0 references

1 reference