Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation (Q28609772)

3 February 2017

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1 November 2019

title

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation (English)

2 references

3 February 2017

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1 November 2019

9

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1 November 2019

author name string

Yunping Lin

2

2 references

3 February 2017

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1 November 2019

Weili Ma

3

2 references

3 February 2017

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1 November 2019

Hong Wu

4

2 references

3 February 2017

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1 November 2019

Benedicte Lemmers

5

2 references

3 February 2017

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1 November 2019

Stephen Chung

6

2 references

3 February 2017

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1 November 2019

Guillermina Lozano

8

2 references

3 February 2017

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1 November 2019

Samuel Benchimol

10

2 references

3 February 2017

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1 November 2019

Roger P Leng

1

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1 November 2019

John M Parant

7

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1 November 2019

language of work or name

English

0 references

publication date

1 March 2003

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1 November 2019

2 references

3 February 2017

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1 November 2019

volume

112

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3 February 2017

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1 November 2019

issue

6

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3 February 2017

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1 November 2019

page(s)

779-791

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Conformation-dependent phosphorylation of p53.

1 November 2019

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Post-translational modifications and activation of p53 by genotoxic stresses

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Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression.

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mdm2 expression is induced by wild type p53 activity

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Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

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RING domains: master builders of molecular scaffolds?

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Mapping of the p53 and mdm-2 Interaction Domains

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Definition of a consensus binding site for p53

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

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JNK targets p53 ubiquitination and degradation in nonstressed cells

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Identification of a sequence element from p53 that signals for Mdm2-targeted degradation

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Monoclonal antibodies specific for simian virus 40 tumor antigens

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Mdm2 promotes the rapid degradation of p53

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7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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MdmX protects p53 from Mdm2-mediated degradation

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Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin

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7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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7 January 2021

How the cyclin became a cyclin: regulated proteolysis in the cell cycle

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

p53, the cellular gatekeeper for growth and division

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

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7 January 2021

Deacetylation of p53 modulates its effect on cell growth and apoptosis

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7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

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7 January 2021

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

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7 January 2021

Why is p53 acetylated?

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Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

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Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53

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7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Surfing the p53 network

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The p53-mdm-2 autoregulatory feedback loop

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Identification and classification of p53-regulated genes

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Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

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1 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017