Proximal events in Wnt signal transduction (Q29616162)

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31 January 2020

review article

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title

Proximal events in Wnt signal transduction (English)

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1

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Randall T. Moon

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2

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author name string

Angers S

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Moon RT

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publication date

1 July 2009

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Nature Reviews Molecular Cell Biology

31 January 2020

published in

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volume

10

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issue

7

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31 January 2020

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468-477

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The Wnt signaling pathway in development and disease

31 January 2020

cites work

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The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

31 March 2020

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Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.

31 March 2020

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Advances in signaling in vertebrate regeneration as a prelude to regenerative medicine.

31 March 2020

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Distinct Wnt signaling pathways have opposing roles in appendage regeneration

31 March 2020

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

31 March 2020

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A frizzled homolog functions in a vertebrate Wnt signaling pathway

31 March 2020

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Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

31 March 2020

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Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

31 March 2020

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Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization

31 March 2020

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Wnt-mediated axon guidance via the Drosophila Derailed receptor

31 March 2020

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Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

31 March 2020

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C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling

31 March 2020

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WNT and beta-catenin signalling: diseases and therapies

31 March 2020

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Wnt/beta-catenin signaling in development and disease

31 March 2020

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beta-catenin destruction complex: insights and questions from a structural perspective

31 March 2020

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Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea

31 March 2020

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Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

31 March 2020

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Frizzled-7 signalling controls tissue separation during Xenopus gastrulation

31 March 2020

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Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

31 March 2020

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Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development

31 March 2020

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Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

31 March 2020

1 reference

Noncanonical Wnt signaling promotes apoptosis in thymocyte development

31 March 2020

1 reference

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

31 March 2020

1 reference

Activation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) function

31 March 2020

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Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins

31 March 2020

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Trimeric G protein-dependent frizzled signaling in Drosophila

31 March 2020

1 reference

Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A.

31 March 2020

1 reference

Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.

31 March 2020

1 reference

Wnt-5a has tumor suppressor activity in thyroid carcinoma

31 March 2020

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Wnt5a is required for cardiac outflow tract septation in mice

31 March 2020

1 reference

Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/cGMP/Ca2+ pathway

31 March 2020

1 reference

The Wnt/calcium pathway activates NF-AT and promotes ventral cell fate in Xenopus embryos

31 March 2020

1 reference

Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10

31 March 2020

1 reference

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

31 March 2020

1 reference

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

31 March 2020

1 reference

The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation

31 March 2020

1 reference

Activation of Gβγ signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation

31 March 2020

1 reference

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

31 March 2020

1 reference

Regulation of G protein-initiated signal transduction in yeast: paradigms and principles

31 March 2020

1 reference

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

31 March 2020

1 reference

Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation

31 March 2020

1 reference

Smoothened activates Galphai-mediated signaling in frog melanophores

31 March 2020

1 reference

Hedgehog signaling: is Smo a G protein-coupled receptor?

31 March 2020

1 reference

G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling

31 March 2020

1 reference

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

31 March 2020

1 reference

31 March 2020

1 reference

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

31 March 2020

1 reference

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

31 March 2020

1 reference

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

31 March 2020

1 reference

A mechanism for Wnt coreceptor activation

31 March 2020

1 reference

Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.

31 March 2020

1 reference

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

31 March 2020

1 reference

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

31 March 2020

1 reference

Components of wingless signalling in Drosophila.

31 March 2020

1 reference

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

31 March 2020

1 reference

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

31 March 2020

1 reference

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

31 March 2020

1 reference

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

31 March 2020

1 reference

The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles

31 March 2020

1 reference

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

31 March 2020

1 reference

The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases

31 March 2020

1 reference

31 March 2020

1 reference

The Caenorhabditis elegans Ror RTK CAM-1 inhibits EGL-20/Wnt signaling in cell migration

31 March 2020

1 reference

Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system

31 March 2020

1 reference

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

31 March 2020

1 reference

Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway

31 March 2020

1 reference

Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

31 March 2020

1 reference

The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

31 March 2020

1 reference

The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

31 March 2020

1 reference

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

31 March 2020

1 reference

Wise, a context-dependent activator and inhibitor of Wnt signalling

31 March 2020

1 reference

Context-dependent activation or inhibition of Wnt-beta-catenin signaling by Kremen.

31 March 2020

1 reference

Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells

31 March 2020

1 reference

RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs

31 March 2020

1 reference

Axon routing across the midline controlled by the Drosophila Derailed receptor

31 March 2020

1 reference

Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system

31 March 2020

1 reference

Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis

31 March 2020

1 reference

Regulation of cerebral cortical size by control of cell cycle exit in neural precursors

31 March 2020

1 reference

beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system

31 March 2020

1 reference

The primary cilium as the cell's antenna: signaling at a sensory organelle

31 March 2020

1 reference

The immotile-cilia syndrome. A congenital ciliary abnormality as an etiologic factor in chronic airway infections and male sterility

31 March 2020

1 reference

Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

31 March 2020

1 reference

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

31 March 2020

1 reference

Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome

31 March 2020

1 reference

Cilia and developmental signaling

31 March 2020

1 reference

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

31 March 2020

1 reference

Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

31 March 2020

1 reference

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

31 March 2020

1 reference

Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response

31 March 2020

1 reference

Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms

31 March 2020

1 reference

Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways

31 March 2020

1 reference

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

31 March 2020

1 reference

Functional genomic analysis of the Wnt-wingless signaling pathway

31 March 2020

1 reference

A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer

31 March 2020

1 reference

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

31 March 2020

1 reference

Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway.

31 March 2020

1 reference

12 December 2020

New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening

1 reference

12 December 2020

The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling

1 reference

12 December 2020

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

1 reference

12 December 2020

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31 January 2020

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