DNA damage activates p53 through a phosphorylation-acetylation cascade (Q29616294)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9744860

30 April 2017

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1 reference

Sakaguchi K

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9744860

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Herrera JE

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Saito S

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Miki T

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Bustin M

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Vassilev A

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Anderson CW

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Appella E

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9744860

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9744860

30 April 2017

language of work or name

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30 April 2017

publication date

15 September 1998

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30 April 2017

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volume

12

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issue

18

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page(s)

2831-41

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describes a project that uses

30 April 2017

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC317174/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Enhanced phosphorylation of p53 by ATM in response to DNA damage

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

30 April 2017

1 reference

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BRCA1 regulates p53-dependent gene expression

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

RNA helicase A mediates association of CBP with RNA polymerase II

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Recruitment of p300/CBP in p53-dependent signal pathways

30 April 2017

1 reference

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Binding and modulation of p53 by p300/CBP coactivators

30 April 2017

1 reference

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Synergistic activation of transcription by CBP and p53

30 April 2017

1 reference

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Regulation of p53 stability by Mdm2

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Mdm2 promotes the rapid degradation of p53

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

p53, the cellular gatekeeper for growth and division

30 April 2017

1 reference

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A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

30 April 2017

1 reference

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30 April 2017

p53: puzzle and paradigm

1 reference

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

30 April 2017

1 reference

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The p53-mdm-2 autoregulatory feedback loop

30 April 2017

1 reference

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WAF1, a potential mediator of p53 tumor suppression

30 April 2017

1 reference

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

U.V.C.-induction of p53 activation and accumulation is dependent on cell cycle and pathways involving protein synthesis and phosphorylation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Stabilization and activation of p53 are regulated independently by different phosphorylation events

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Prolonged p53 protein accumulation in trichothiodystrophy fibroblasts dependent on unrepaired pyrimidine dimers on the transcribed strands of cellular genes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Nuclear and non-nuclear targets of genotoxic agents in the induction of gene expression. Shared principles in yeast, rodents, man and plants

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

DNA damage induces phosphorylation of the amino terminus of p53

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Acetylation of general transcription factors by histone acetyltransferases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

p53 transactivation and protein accumulation are independently regulated by UV light in different phases of the cell cycle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Human p53 expressed in baculovirus-infected Sf9 cells displays a two-dimensional isoform pattern identical to wild-type p53 from human cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Specific sequences from the carboxyl terminus of human p53 gene product form anti-parallel tetramers in solution

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Two distinct signaling pathways activate the latent DNA binding function of p53 in a casein kinase II-independent manner.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

A transcriptionally active DNA-binding site for human p53 protein complexes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Regulation of the specific DNA binding function of p53

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Multisite phosphorylation and the integration of stress signals at p53.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

p53 domains: identification and characterization of two autonomous DNA-binding regions.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317174

Chemical synthesis of phosphorylated peptides of the carboxy-terminal domain of human p53 by a segment condensation method

26 November 2018

1 reference

12 December 2020

CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein

1 reference

12 December 2020

The histone acetyltransferase activity of human GCN5 and PCAF is stabilized by coenzymes

1 reference

12 December 2020

Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53

1 reference

12 December 2020

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.12.18.2831

1 reference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9744860

2 references

30 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9744860

PubMed publication ID

2 references

30 April 2017