Can autophagy promote longevity? (Q34135551)

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English	Can autophagy promote longevity?	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

title

Can autophagy promote longevity? (English)

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stated in

Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

main subject

autophagy

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author

Nektarios Tavernarakis

series ordinal

2

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Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

Guido Kroemer

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3

object named as

Guido Kroemer

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author name string

Frank Madeo

series ordinal

1

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Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

publication date

1 September 2010

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Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

published in

Nature Cell Biology

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stated in

Europe PubMed Central

PubMed publication ID

20811357

retrieved

31 July 2017

volume

12

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Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

issue

9

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Europe PubMed Central

PubMed publication ID

20811357

retrieved

31 July 2017

page(s)

842-846

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Europe PubMed Central

PubMed publication ID

20811357

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31 July 2017

cites work

Autophagy is required for dietary restriction-mediated life span extension in C. elegans

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Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans.

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21 January 2018

Autophagy is required for extension of yeast chronological life span by rapamycin

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21 January 2018

Permeases recycle amino acids resulting from autophagy.

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21 January 2018

Molecular regulation of apoptosis in fast plantaris muscles of aged rats

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21 January 2018

Rapamycin decelerates cellular senescence

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21 January 2018

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

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21 January 2018

Autophagy regulates ageing in C. elegans.

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21 January 2018

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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inferred from PubMed ID database lookup

Recent developments in yeast aging

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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inferred from PubMed ID database lookup

Efficient cross-presentation depends on autophagy in tumor cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent roles of RAS1 and RAS2 in yeast longevity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of autophagy by cytoplasmic p53

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective autophagy leads to cancer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related decline in chaperone-mediated autophagy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The life span-prolonging effect of sirtuin-1 is mediated by autophagy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Ageing and eating.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of autophagy by spermidine promotes longevity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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inferred from PubMed ID database lookup

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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inferred from PubMed ID database lookup

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Inhibition of macroautophagy triggers apoptosis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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inferred from PubMed ID database lookup

Sirtuins in aging and age-related disease.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy and aging: the importance of maintaining "clean" cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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Autophagy for the avoidance of neurodegeneration

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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The roles of intracellular protein-degradation pathways in neurodegeneration

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of putative apoptosis factors leads to lifespan extension in the fungal ageing model Podospora anserina

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Eating to exit: autophagy-enabled senescence revealed.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy genes are essential for dauer development and life-span extension in C. elegans

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extension of chronological life span in yeast by decreased TOR pathway signaling

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Cytoprotective roles for autophagy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ongoing saga of sirtuins and aging

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol is not a direct activator of SIRT1 enzyme activity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H4 lysine 16 acetylation regulates cellular lifespan

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Autophagic cell death: the story of a misnomer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Exercise training attenuates age-induced elevation in Bax/Bcl-2 ratio, apoptosis, and remodeling in the rat heart.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Decoding cell death signals in inflammation and immunity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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The effects of p53 on whole organism longevity are mediated by autophagy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Polyamine-rich food decreases age-associated pathology and mortality in aged mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy mediates the mitotic senescence transition

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

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Autophagy in the Pathogenesis of Disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol improves health and survival of mice on a high-calorie diet

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

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Autophagy suppresses tumorigenesis through elimination of p62

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A caspase-related protease regulates apoptosis in yeast

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sir2 blocks extreme life-span extension.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/20811357

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB0910-842

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20811357

retrieved

31 July 2017

Dimensions Publication ID

1012707120

0 references

PubMed publication ID

20811357

1 reference

stated in

Europe PubMed Central

PubMed publication ID

20811357

retrieved

31 July 2017

ResearchGate publication ID

46111075

0 references

 

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