Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice (Q34166819)

31 July 2017

title

Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice (English)

1 reference

31 July 2017

0 references

1 reference

Giuseppe Cifelli

11

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Gabriella De Vita

Gabriella De Vita

12

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Tommaso Russo

Tommaso Russo

9

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Carmine Vecchione

Carmine Vecchione

2

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Giuseppe Lembo

Giuseppe Lembo

13

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author name string

Nicoletta Potenza

1

1 reference

31 July 2017

Antonella Notte

3

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31 July 2017

Assunta De Rienzo

4

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31 July 2017

Annamaria Rosica

5

1 reference

31 July 2017

Lisa Bauer

6

1 reference

31 July 2017

Andrea Affuso

7

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31 July 2017

Mario De Felice

8

1 reference

31 July 2017

Roberta Poulet

10

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31 July 2017

Roberto Di Lauro

14

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31 July 2017

publication date

1 May 2005

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31 July 2017

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31 July 2017

volume

6

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31 July 2017

issue

5

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31 July 2017

page(s)

432-437

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An acylation cycle regulates localization and activity of palmitoylated Ras isoforms

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

An integrated regulatory network controlling survival and migration in thyroid organogenesis

28 July 2018

1 reference

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Dysregulation of HSG triggers vascular proliferative disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Sizing up the heart: development redux in disease.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Ca2+/calmodulin binds and dissociates K-RasB from membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Targeting RAS signalling pathways in cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

28 July 2018

A Ras by any other name

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Activation of the small GTP-binding protein Ras in the heart by hypertrophic agonists

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Understanding Ras: 'it ain't over 'til it's over'.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

The murine N-ras gene is not essential for growth and development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Depalmitoylation of CAAX motif proteins. Protein structural determinants of palmitate turnover rate.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

The p21 ras C-terminus is required for transformation and membrane association

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Dynamic fatty acylation of p21N-ras

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400397

Ras proteins: different signals from different locations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400397

gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400397

RAS oncogenes: the first 30 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400397

Cardiovascular influences of alpha1b-adrenergic receptor defect in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400397

On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1299307

Calcium and heart failure: the cycle game

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15864294

12 December 2020

inferred from PubMed ID database lookup

Unravelling Ras signals in cardiovascular disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15864294

12 December 2020

inferred from PubMed ID database lookup

K-ras is essential for the development of the mouse embryo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15864294

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/SJ.EMBOR.7400397

1 reference

release_4yqawt3tjnbppaha5mt4ug5afm

31 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4yqawt3tjnbppaha5mt4ug5afm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1299307

1 reference

31 July 2017

1 reference