G-protein-coupled receptors and signaling networks: emerging paradigms. (Q34296103)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11431032%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

review article

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title

G-protein-coupled receptors and signaling networks: emerging paradigms (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11431032%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

9 November 2019

main subject

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author

J. Silvio Gutkind

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11431032%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

M J Marinissen

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11431032%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 July 2001

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Trends in Pharmacological Sciences

9 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11431032%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

22

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9 November 2019

issue

7

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9 November 2019

page(s)

368-376

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Modelling G-protein-coupled receptors for drug design

9 November 2019

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Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation

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Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s.

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Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells

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Two G protein oncogenes in human endocrine tumors

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Differential effects of protein kinase A on Ras effector pathways

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Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

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Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

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Stat3-mediated transformation of NIH-3T3 cells by the constitutively active Q205L Galphao protein.

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A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

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7 January 2021

Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product

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G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

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The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

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Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

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Rho as a mediator of G protein-coupled receptor signaling.

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Transcriptional regulation by MAP kinases

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The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

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7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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7 January 2021

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7 January 2021

Divergent signaling pathways link focal adhesion kinase to mitogen-activated protein kinase cascades. Evidence for a role of paxillin in c-Jun NH(2)-terminal kinase activation

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7 January 2021

Regulation of Apoptosis by α-Subunits of G12 and G13 Proteins via Apoptosis Signal-regulating Kinase-1

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Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

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7 January 2021

Signal transduction by the JNK group of MAP kinases

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7 January 2021

The p38 signal transduction pathway: activation and function

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Activation of p38 mitogen-activated protein kinase by signaling through G protein-coupled receptors. Involvement of Gbetagamma and Galphaq/11 subunits

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Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit

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Involvement of protein kinase C and Src family tyrosine kinase in Galphaq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase

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The mitogen-activated protein kinase p38-2 is necessary for the inhibition of N-type calcium current by bradykinin.

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Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

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Signaling from G protein-coupled receptors to ERK5/Big MAPK 1 involves Galpha q and Galpha 12/13 families of heterotrimeric G proteins. Evidence for the existence of a novel Ras AND Rho-independent pathway

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Molecular tinkering of G protein-coupled receptors: an evolutionary success

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Signaling through scaffold, anchoring, and adaptor proteins

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7 January 2021

Heptahelical receptor signaling: beyond the G protein paradigm.

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11431032%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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