Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene (Q34389036)

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English	Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene (English)

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Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

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inferred from title

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object named as

Wendy DuBois

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Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Valery Bliskovsky

1

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Europe PubMed Central

PubMed publication ID

1 August 2017

Edward S Ramsay

2

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Europe PubMed Central

PubMed publication ID

1 August 2017

John Scott

3

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Europe PubMed Central

PubMed publication ID

1 August 2017

Wei Shi

5

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Europe PubMed Central

PubMed publication ID

1 August 2017

Shuling Zhang

6

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Europe PubMed Central

PubMed publication ID

1 August 2017

Xiaolan Qian

7

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Europe PubMed Central

PubMed publication ID

1 August 2017

Douglas R Lowy

8

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Europe PubMed Central

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1 August 2017

Beverly A Mock

9

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Europe PubMed Central

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1 August 2017

language of work or name

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publication date

21 November 2003

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Europe PubMed Central

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1 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

1 August 2017

100

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Europe PubMed Central

PubMed publication ID

1 August 2017

25

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Europe PubMed Central

PubMed publication ID

1 August 2017

14982-14987

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Europe PubMed Central

PubMed publication ID

1 August 2017

p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

TGF-beta antagonists: why suppress a tumor suppressor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

TGF-beta signaling: positive and negative effects on tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Activation and activities of the p53 tumour suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Regulation of translation initiation by FRAP/mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Efficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

TOR, a central controller of cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

cDNA cloning and expression analysis of new members of the mammalian F-box protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

A truncated form of mannose-binding lectin-associated serine protease (MASP)-2 expressed by alternative polyadenylation is a component of the lectin complement pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Alpha 4 associates with protein phosphatases 2A, 4, and 6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Regulation of eIF-4E BP1 phosphorylation by mTOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

A second serine protease associated with mannan-binding lectin that activates complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Immunopharmacology of rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Addition of constitutive c-myc expression to Abelson murine leukemia virus changes the phenotype of the cells transformed by the virus from pre-B-cell lymphomas to plasmacytomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Interleukin 6 is essential for in vivo development of B lineage neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Control of p70 s6 kinase by kinase activity of FRAP in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Immunoglobulin-producing tumors and myeloma proteins of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Establishment of two interleukin 6 (B cell stimulatory factor 2/interferon beta 2)-dependent human bone marrow-derived myeloma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Interleukin-6 is the central tumor growth factor in vitro and in vivo in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Establishment and characterization of a human prostatic carcinoma cell line (PC-3)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

6 July 2018

Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

The ATRs, ATMs, and TORs are giant HEAT repeat proteins.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

27 October 2018

Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=299869

27 October 2018

The role of p16INK4a (Cdkn2a) in mouse plasma cell tumors

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

FRAP DNA-dependent protein kinase mediates a late signal transduced from ultraviolet-induced DNA damage

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

Transcription inhibitors stimulate translation of 5' TOP mRNAs through activation of S6 kinase and the mTOR/FRAP signalling pathway

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2431627100

21 January 2018

The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/14634209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two genes on chromosome 4 that determine resistance to plasmacytoma induction in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14634209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonrandom chromosomal change (trisomy 11) in murine plasmacytomas induced by an ABL-MYC retrovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14634209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.2431627100

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2003PNAS..10014982B

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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