CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells (Q34436650)

2 August 2017

title

CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells (English)

1 reference

2 August 2017

0 references

Klaus H Kaestner

6

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author name string

Soona Shin

1

1 reference

2 August 2017

John Le Lay

2

1 reference

2 August 2017

Logan J Everett

3

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2 August 2017

Rana Gupta

4

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2 August 2017

Kiran Rafiq

5

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2 August 2017

language of work or name

1 reference

23 August 2014

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2 August 2017

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2 August 2017

volume

3

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2 August 2017

issue

8

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2 August 2017

page(s)

803-812

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Epigenomic plasticity enables human pancreatic α to β cell reprogramming.

2 August 2017

cites work

1 reference

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6 July 2018

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Antiapoptotic actions of exendin-4 against hypoxia and cytokines are augmented by CREB.

6 July 2018

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Two incretin hormones GLP-1 and GIP: comparison of their actions in insulin secretion and β cell preservation.

6 July 2018

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6 July 2018

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Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice

6 July 2018

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CREB Inhibits AP-2α Expression to Regulate the Malignant Phenotype of Melanoma

6 July 2018

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

6 July 2018

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Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells

6 July 2018

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Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes.

6 July 2018

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Roles of cAMP signalling in insulin granule exocytosis

6 July 2018

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CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis

6 July 2018

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The transcriptional response of the islet to pregnancy in mice

6 July 2018

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Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop

6 July 2018

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6 July 2018

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Sex differences in the effects of acute and chronic stress and recovery after long-term stress on stress-related brain regions of rats

6 July 2018

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Expression profile of CREB knockdown in myeloid leukemia cells

6 July 2018

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An overview of incretin clinical trials

6 July 2018

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Cis-regulatory modules in the mammalian liver: composition depends on strength of Foxa2 consensus site

6 July 2018

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Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells

6 July 2018

1 reference

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Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway

6 July 2018

1 reference

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Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14.

6 July 2018

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Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets.

6 July 2018

1 reference

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Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation

6 July 2018

1 reference

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WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Exendin-4 induction of cyclin D1 expression in INS-1 beta-cells: involvement of cAMP-responsive element

6 July 2018

1 reference

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Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis

6 July 2018

1 reference

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Mutation at position -132 in the islet amyloid polypeptide ( IAPP) gene promoter enhances basal transcriptional activity through a new CRE-like binding site

6 July 2018

1 reference

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Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells

6 July 2018

1 reference

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p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells

6 July 2018

1 reference

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cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis

6 July 2018

1 reference

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Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice

6 July 2018

1 reference

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

6 July 2018

1 reference

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Recombineering: a powerful new tool for mouse functional genomics

6 July 2018

1 reference

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Transcriptional regulation by the phosphorylation-dependent factor CREB

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Transcription factors responsive to cAMP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Transcription of the rat glucagon gene by the cyclic AMP response element-binding protein CREB is modulated by adjacent CREB-associated proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Distinct properties of the cAMP-responsive element of the rat insulin I gene.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

The use of ficoll in the preparation of viable islets of langerhans from the rat pancreas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

The transcription factor CREB has no non-redundant functions in hepatic glucose metabolism in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Stabilization of beta-catenin impacts pancreas growth.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Sex difference in the response of melanin-concentrating hormone neurons in the lateral hypothalamic area to glucose, as revealed by the expression of phosphorylated cyclic adenosine 3',5'-monophosphate response element-binding protein

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

A selective increase in phosphorylation of cyclic AMP response element-binding protein in hippocampal CA1 region of male, but not female, rats following contextual fear and passive avoidance conditioning

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Modulation of anxiety-like behavior and morphine dependence in CREB-deficient mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Adrenergic signals direct rhythmic expression of transcriptional repressor CREM in the pineal gland.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4216406

Oxidative stress induces p21 expression in pancreatic islet cells: possible implication in beta-cell dysfunction

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25379405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25379405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25379405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLMET.2014.08.001

1 reference

2 August 2017

1 reference

2 August 2017

1 reference