Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53. (Q34499763)

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English	Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Lack of p53 affects the expression of several brain mitochondrial proteins: insights from proteomics into important pathways regulated by p53. (English)

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Europe PubMed Central

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2 August 2017

Giovanna Cenini

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Giovanna Cenini

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Eugenio Barone

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Cesare Mancuso

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D Allan Butterfield

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D Allan Butterfield

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2 August 2017

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Ada Fiorini

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2 August 2017

Rukhsana Sultana

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2 August 2017

Marzia Perluigi

5

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2 August 2017

Jian Cai

7

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2 August 2017

Jon B Klein

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2 August 2017

Daret St Clair

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2 August 2017

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publication date

27 November 2012

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Europe PubMed Central

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2 August 2017

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2 August 2017

7

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2 August 2017

11

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Europe PubMed Central

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2 August 2017

e49846

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Creative Commons Attribution 4.0 International

27 November 2012

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April 2022 Public Data File from Crossref

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1 reference

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Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B.

1 reference

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Glutathionylation of the pro-apoptotic protein p53 in Alzheimer's disease brain: implications for AD pathogenesis

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Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice

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Elevated levels of pro-apoptotic p53 and its oxidative modification by the lipid peroxidation product, HNE, in brain from subjects with amnestic mild cognitive impairment and Alzheimer's disease

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Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease

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A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury

1 reference

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ROS and p53: a versatile partnership

1 reference

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Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

1 reference

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Coping with stress: multiple ways to activate p53.

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p53: at the crossroad between cancer and ageing

1 reference

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Outcomes of p53 activation--spoilt for choice

1 reference

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1 reference

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Specificity protein 1-dependent p53-mediated suppression of human manganese superoxide dismutase gene expression

1 reference

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Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

1 reference

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The antioxidant function of the p53 tumor suppressor

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Calcium, ATP, and ROS: a mitochondrial love-hate triangle

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Modulation of mammalian life span by the short isoform of p53.

1 reference

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VDAC2 inhibits BAK activation and mitochondrial apoptosis

1 reference

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Oxidation of 4-hydroxy-2-nonenal by succinic semialdehyde dehydrogenase (ALDH5A)

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Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis

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Proteomic identification of nitrated proteins in Alzheimer's disease brain

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Decision making by p53: life, death and cancer

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Mitochondrial oxidation of 4-hydroxy-2-nonenal in rat cerebral cortex

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Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability.

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p53 mutant mice that display early ageing-associated phenotypes

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Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome

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Deranged expression of molecular chaperones in brains of patients with Alzheimer's disease

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Deregulated manganese superoxide dismutase expression and resistance to oxidative injury in p53-deficient cells

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Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71.

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Reciprocal down-regulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis

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Regulation of the human hsp70 promoter by p53

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Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Abeta(1-42): implications for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23209608

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based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0049846

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Europe PubMed Central

PubMed publication ID

2 August 2017

2012PLoSO...749846F

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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