The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death (Q34914286)

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English	The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death (English)

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Burkhard Kleuser

7

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Burkhard Kleuser

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Europe PubMed Central

PubMed publication ID

5 August 2017

Josef Pfeilschifter

8

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Josef Pfeilschifter

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5 August 2017

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Oleksandr Pastukhov

1

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5 August 2017

Stephanie Schwalm

2

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Europe PubMed Central

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5 August 2017

Uwe Zangemeister-Wittke

3

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Europe PubMed Central

PubMed publication ID

5 August 2017

Doriano Fabbro

4

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Europe PubMed Central

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5 August 2017

Frederic Bornancin

5

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5 August 2017

Lukasz Japtok

6

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5 August 2017

Andrea Huwiler

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5 August 2017

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publication date

1 December 2014

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5 August 2017

British Journal of Pharmacology

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5 August 2017

171

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PubMed publication ID

5 August 2017

24

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Europe PubMed Central

PubMed publication ID

5 August 2017

5829-5844

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Europe PubMed Central

PubMed publication ID

5 August 2017

The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

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The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

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The cell-cycle regulator CDK4: an emerging therapeutic target in melanoma

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Cdks, cyclins and CKIs: roles beyond cell cycle regulation

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Effects of siRNA‑mediated Cdc2 silencing on MG63 cell proliferation and apoptosis

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8 July 2018

The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death

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8 July 2018

Ceramide 1-phosphate stimulates proliferation of C2C12 myoblasts

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Serine palmitoyltransferase inhibitor myriocin induces growth inhibition of B16F10 melanoma cells through G(2) /M phase arrest

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Ceramide kinase: The first decade

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8 July 2018

Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage

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8 July 2018

Sphingosine 1-phosphate and cancer

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8 July 2018

Inhibition of p53 sensitizes MCF-7 cells to ceramide treatment.

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8 July 2018

An overview of Cdk1-controlled targets and processes

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8 July 2018

Subcellular localization of ceramide kinase and ceramide kinase-like protein requires interplay of their Pleckstrin Homology domain-containing N-terminal regions together with C-terminal domains

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8 July 2018

Ceramide 1-phosphate (C1P) promotes cell migration Involvement of a specific C1P receptor

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8 July 2018

A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides

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8 July 2018

Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor

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8 July 2018

Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin

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8 July 2018

Redundant ubiquitin ligase activities regulate wee1 degradation and mitotic entry.

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8 July 2018

Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy

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8 July 2018

Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation

1 reference

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8 July 2018

Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramide-1-phosphate promotes cell survival through activation of the phosphatidylinositol 3-kinase/protein kinase B pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramide kinase is a mediator of calcium-dependent degranulation in mast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramides modulate programmed cell death in plants

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

Ceramide kinase, a novel lipid kinase. Molecular cloning and functional characterization

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290720

8 July 2018

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

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8 July 2018

Growth and cell cycle abnormalities of fibroblasts from Tangier disease patients

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8 July 2018

Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.

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8 July 2018

The formation of ceramide-1-phosphate during neutrophil phagocytosis and its role in liposome fusion

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8 July 2018

A new, simple, nonradioactive, nontoxic in vitro assay to monitor corneal endothelial cell viability

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8 July 2018

Stimulation of DNA synthesis by natural ceramide 1-phosphate

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The cell cycle and regulation of cancer cell growth

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Ceramide 1-phosphate phosphatase activity in brain

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Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest

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Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. Correlation with cyclin-dependent kinases

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8 July 2018

Role for ceramide in cell cycle arrest.

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8 July 2018

Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: antagonism by cell-permeable ceramides

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8 July 2018

Synaptic vesicle ceramide kinase. A calcium-stimulated lipid kinase that co-purifies with brain synaptic vesicles

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8 July 2018

Ceramide kinase profiling by mass spectrometry reveals a conserved phosphorylation pattern downstream of the catalytic site

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21 January 2018

Assessment and prognostic significance of mitotic index using the mitosis marker phospho-histone H3 in low and intermediate-grade infiltrating astrocytomas

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21 January 2018

Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype

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21 January 2018

Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro

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Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts.

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21 January 2018

Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer

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Effects of ceramide-1-phosphate on cultured cells: dependence on dodecane in the vehicle.

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Neutropenia with Impaired Immune Response to Streptococcus pneumoniae in Ceramide Kinase-Deficient Mice

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Regulation of cyclin-dependent kinase 2 activity by ceramide

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Involvement of p27(kip1) in ceramide-mediated apoptosis in HL-60 cells

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Induction of p21 during ceramide-mediated apoptosis in human hepatocarcinoma cells

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10.1111/BPH.12886

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Europe PubMed Central

PubMed publication ID

5 August 2017

release_uvf4eropz5c2tgvp22p6xlt55m

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https://api.fatcat.wiki/v0/release/uvf4eropz5c2tgvp22p6xlt55m

24 November 2022

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Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

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Europe PubMed Central

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5 August 2017

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