Primary microRNA transcripts are processed co-transcriptionally. (Q34931030)

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20 January 2020

title

Primary microRNA transcripts are processed co-transcriptionally (English)

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20 January 2020

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2

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Nicholas Jarvis Proudfoot

20 January 2020

6

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20 January 2020

author name string

Mariangela Morlando

1

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20 January 2020

Natalia Gromak

3

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20 January 2020

Francesca Pagano

4

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20 January 2020

Irene Bozzoni

5

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20 January 2020

publication date

1 September 2008

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Nature Structural & Molecular Biology

20 January 2020

published in

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20 January 2020

volume

15

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20 January 2020

issue

9

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20 January 2020

page(s)

902-909

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Physical Isolation of Nascent RNA Chains Transcribed by RNA Polymerase II: Evidence for Cotranscriptional Splicing

20 January 2020

cites work

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MicroRNA biogenesis: coordinated cropping and dicing

21 January 2018

1 reference

Human let-7 stem-loop precursors harbor features of RNase III cleavage products

31 March 2020

1 reference

Processing of primary microRNAs by the Microprocessor complex

31 March 2020

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The Microprocessor complex mediates the genesis of microRNAs

31 March 2020

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Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

31 March 2020

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Nuclear export of microRNA precursors

31 March 2020

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Control of translation and mRNA degradation by miRNAs and siRNAs

31 March 2020

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31 March 2020

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Asymmetry in the assembly of the RNAi enzyme complex

31 March 2020

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MicroRNA maturation: stepwise processing and subcellular localization

31 March 2020

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Genomic analysis of human microRNA transcripts

31 March 2020

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New microRNAs from mouse and human

31 March 2020

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Identification of mammalian microRNA host genes and transcription units

31 March 2020

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Processing of intronic microRNAs

31 March 2020

1 reference

Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

31 March 2020

1 reference

EST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in normal human and mouse tissues

31 March 2020

1 reference

U24, a novel intron-encoded small nucleolar RNA with two 12 nt long, phylogenetically conserved complementaritiesm to 28S rRNA

31 March 2020

1 reference

TOP promoter elements control the relative ratio of intron-encoded snoRNA versus spliced mRNA biosynthesis

31 March 2020

1 reference

Splicing-dependent and -independent modes of assembly for intron-encoded box C/D snoRNPs in mammalian cells

31 March 2020

1 reference

Cotranscriptional recognition of human intronic box H/ACA snoRNAs occurs in a splicing-independent manner.

31 March 2020

1 reference

Cotranscriptional recruitment of the pseudouridylsynthetase Cbf5p and of the RNA binding protein Naf1p during H/ACA snoRNP assembly

31 March 2020

1 reference

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

31 March 2020

1 reference

Identification of novel genes coding for small expressed RNAs

31 March 2020

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MicroRNA genes are transcribed by RNA polymerase II

31 March 2020

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RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes.

31 March 2020

1 reference

Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing

31 March 2020

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Exon tethering in transcription by RNA polymerase II

31 March 2020

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Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA.

31 March 2020

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Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma.

31 March 2020

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Extensive post-transcriptional regulation of microRNAs and its implications for cancer

31 March 2020

1 reference

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

31 March 2020

1 reference

Molecular dissection of mammalian RNA polymerase II transcriptional termination

31 March 2020

1 reference

Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells

31 March 2020

1 reference

Excess of microRNAs in large and very 5' biased introns

31 March 2020

1 reference

Novel RNAs identified from an in-depth analysis of the transcriptome of human chromosomes 21 and 22

31 March 2020

1 reference

Discovery of tissue-specific exons using comprehensive human exon microarrays

31 March 2020

1 reference

Integrating mRNA processing with transcription

31 March 2020

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The C-terminal domain of RNA Pol II helps ensure that editing precedes splicing of the GluR-B transcript

31 March 2020

1 reference

The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

31 March 2020

1 reference

Pause sites promote transcriptional termination of mammalian RNA polymerase II

31 March 2020

1 reference

Turnover and function of noncoding RNA polymerase II transcripts.

31 March 2020

1 reference

RNAse III-mediated degradation of unspliced pre-mRNAs and lariat introns

31 March 2020

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SnoRNP biogenesis meets Pre-mRNA splicing

31 March 2020

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Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins

31 March 2020

1 reference

The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a

31 March 2020

1 reference

RNAi-mediated PTB depletion leads to enhanced exon definition

31 March 2020

1 reference

Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

31 March 2020

1 reference

The cotranscriptional assembly of snoRNPs controls the biosynthesis of H/ACA snoRNAs in Saccharomyces cerevisiae

31 March 2020

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Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster

31 March 2020

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Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II

31 March 2020

1 reference

31 March 2020

The microRNA Registry

1 reference

BLAT—The BLAST-Like Alignment Tool

31 March 2020

1 reference

miRGen: a database for the study of animal microRNA genomic organization and function

31 March 2020

1 reference

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

31 March 2020

1 reference

Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1475

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20 January 2020

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20 January 2020

PubMed publication ID

19172742

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