Anti-cancer role of SPARC, an inhibitor of adipogenesis (Q35116107)

6 August 2017

1 reference

title

Anti-cancer role of SPARC, an inhibitor of adipogenesis (English)

1 reference

6 August 2017

1 reference

Ganji Purna Chandra Nagaraju

series ordinal

1

1 reference

6 August 2017

Dipali Sharma

series ordinal

2

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6 August 2017

publication date

14 January 2011

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6 August 2017

published in

Cancer Treatment Reviews

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6 August 2017

volume

37

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6 August 2017

issue

7

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6 August 2017

page(s)

559-566

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Relationship and prognostic significance of SPARC and VEGF protein expression in colon cancer

6 August 2017

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Structural basis of sequence-specific collagen recognition by SPARC

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SPARC inhibits adipogenesis by its enhancement of beta-catenin signaling

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SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response

9 July 2018

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Forced expression of MMP9 rescues the loss of angiogenesis and abrogates metastasis of pancreatic tumors triggered by the absence of host SPARC.

9 July 2018

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HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion

9 July 2018

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SPARC-induced increase in glioma matrix and decrease in vascularity are associated with reduced VEGF expression and secretion

9 July 2018

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9 July 2018

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Transcription factor SOX-5 enhances nasopharyngeal carcinoma progression by down-regulating SPARC gene expression

9 July 2018

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Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer

9 July 2018

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Normalization of the ovarian cancer microenvironment by SPARC.

9 July 2018

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A novel interaction between procaspase 8 and SPARC enhances apoptosis and potentiates chemotherapy sensitivity in colorectal cancers

9 July 2018

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SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth

9 July 2018

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Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition

9 July 2018

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Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases

9 July 2018

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Meat consumption and risk of colorectal cancer: a meta-analysis of prospective studies

9 July 2018

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SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

9 July 2018

1 reference

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Invadopodia: specialized cell structures for cancer invasion

9 July 2018

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Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC

9 July 2018

1 reference

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Low or absent SPARC expression in acute myeloid leukemia with MLL rearrangements is associated with sensitivity to growth inhibition by exogenous SPARC protein

9 July 2018

1 reference

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Absence of host-secreted protein acidic and rich in cysteine (SPARC) augments peritoneal ovarian carcinomatosis

9 July 2018

1 reference

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Survey of differentially methylated promoters in prostate cancer cell lines

9 July 2018

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Changes in integrin expression during adipocyte differentiation

9 July 2018

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Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis

9 July 2018

1 reference

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SPARC expression is associated with impaired tumor growth, inhibited angiogenesis and changes in the extracellular matrix

9 July 2018

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Secreted protein acidic and rich in cysteine produced by human melanoma cells modulates polymorphonuclear leukocyte recruitment and antitumor cytotoxic capacity.

9 July 2018

1 reference

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Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy

9 July 2018

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Adiponectin and adiponectin receptors

9 July 2018

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An RNA polymerase II construct synthesizes short-hairpin RNA with a quantitative indicator and mediates highly efficient RNAi

9 July 2018

1 reference

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Aberrant methylation of SPARC in human lung cancers

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC Inhibits Epithelial Cell Proliferation in Part through Stimulation of the Transforming Growth Factor-β–Signaling System

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Osteonectin-Null Mutation Compromises Osteoblast Formation, Maturation, and Survival

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Doxycycline-inducible expression of SPARC/Osteonectin/BM40 in MDA-MB-231 human breast cancer cells results in growth inhibition

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Transcriptional upregulation of SPARC, in response to c-Jun overexpression, contributes to increased motility and invasion of MCF7 breast cancer cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

9 July 2018

1 reference

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Worms gang up on bacteria

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC (secreted protein acidic and rich in cysteine) induces apoptosis in ovarian cancer cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury

9 July 2018

1 reference

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A prospective study of obesity and cancer risk (Sweden).

9 July 2018

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Regulation of death receptor-mediated apoptosis pathways

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Molecular regulation of adipogenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Angiogenesis in cancer and other diseases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Role of transforming growth factor beta in human disease

9 July 2018

1 reference

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Differential expression of osteonectin/SPARC during human prostate cancer progression

9 July 2018

1 reference

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SPARC (osteonectin/BM-40).

9 July 2018

1 reference

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SPARC, a matricellular glycoprotein with important biological functions

9 July 2018

1 reference

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CpG island methylator phenotype in colorectal cancer

9 July 2018

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9 July 2018

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Disruption of the Sparc locus in mice alters the differentiation of lenticular epithelial cells and leads to cataract formation.

9 July 2018

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Machine learning approaches for the prediction of signal peptides and other protein sorting signals

9 July 2018

1 reference

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SPARC: a signal of astrocytic neoplastic transformation and reactive response in human primary and xenograft gliomas

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Regulation of angiogenesis by SPARC and angiostatin: implications for tumor cell biology

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The biology of SPARC, a protein that modulates cell-matrix interactions

9 July 2018

1 reference

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Expression of SPARC during development of the chicken chorioallantoic membrane: evidence for regulated proteolysis in vivo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain that binds calcium and collagen IV

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Role of N-linked glycosylation in human osteonectin. Effect of carbohydrate removal by N-glycanase and site-directed mutagenesis on structure and binding of type V collagen

9 July 2018

1 reference

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SPARC mediates focal adhesion disassembly in endothelial cells through a follistatin-like region and the Ca(2+)-binding EF-hand.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC is a source of copper-binding peptides that stimulate angiogenesis

9 July 2018

1 reference

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Osteonectin, a bone-specific protein linking mineral to collagen

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture

9 July 2018

1 reference

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Isolation and chemical characterization of the phosphoproteins of chicken bone matrix: heterogeneity in molecular weight and composition

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues

9 July 2018

1 reference

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SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix

9 July 2018

1 reference

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How does extracellular matrix control capillary morphogenesis?

9 July 2018

1 reference

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Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Endothelial cell injury in vitro is associated with increased secretion of an Mr 43,000 glycoprotein ligand

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Fibronectin controls capillary endothelial cell growth by modulating cell shape

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Functional mapping of SPARC: peptides from two distinct Ca+(+)-binding sites modulate cell shape

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The Ca2(+)-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The extracellular regulation of growth factor action

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Alternatively activated macrophages regulate extracellular levels of the hormone placental lactogen via receptor-mediated uptake and transcytosis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Synergism between vitamin D and secreted protein acidic and rich in cysteine-induced apoptosis and growth inhibition results in increased susceptibility of therapy-resistant colorectal cancer cells to chemotherapy.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Outcome of children with posterior fossa medulloblastoma: a single institution experience over the decade 1994-2003.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC and Hevin expression correlate with tumour angiogenesis in hepatocellular carcinoma.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Radiation-induced cerebellar glioblastoma at the site of a treated medulloblastoma: case report.

27 September 2018

1 reference

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Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia.

27 September 2018

1 reference

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Extracellular matrix substrata alter adipocyte yield and lipogenesis in primary cultures of stromal-vascular cells from human adipose.

27 September 2018

1 reference

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Clinical significance of secreted protein acidic and rich in cystein in esophageal carcinoma and its relation to carcinoma progression

27 September 2018

1 reference

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SPARC is a key Schwannian-derived inhibitor controlling neuroblastoma tumor angiogenesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Localization of SPARC in developing, mature, and chronically injured human allograft kidneys

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Inhibition of PDGF-stimulated and matrix-mediated proliferation of human vascular smooth muscle cells by SPARC is independent of changes in cell shape or cyclin-dependent kinase inhibitors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC-null mice exhibit accelerated cutaneous wound closure

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC modulates cell growth, attachment and migration of U87 glioma cells on brain extracellular matrix proteins

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The expression of SPARC in adipose tissue and its increased plasma concentration in patients with coronary artery disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Blockade of nuclear factor-kappaB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC regulates the expression of collagen type I and transforming growth factor-beta1 in mesangial cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

SPARC (BM-40, osteonectin) inhibits the mitogenic effect of vascular endothelial growth factor on microvascular endothelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Regulation of low density lipoprotein receptor mRNA levels by estradiol 17beta and chorionic gonadotropin in human placenta.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Understanding adipocyte differentiation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

The expression of the secreted protein acidic and rich in cysteine (SPARC) is associated with the neoplastic progression of human melanoma.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

CD95(APO-1/Fas)-mediated apoptosis in normal and malignant liver, colon, and hematopoietic cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3139810

Integrins in bone recognition and metastasis

27 September 2018

1 reference

12 December 2020

Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma

1 reference

12 December 2020

Overexpression of SPARC protein contrasts with its transcriptional silencing by aberrant hypermethylation of SPARC CpG-rich region in endometrial carcinoma

1 reference

12 December 2020

The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host

1 reference

12 December 2020

Expression of angiopoietin-2 gene and its receptor Tie2 in hepatocellular carcinoma

1 reference

12 December 2020

SPARC/osteonectin is a frequent target for aberrant methylation in pancreatic adenocarcinoma and a mediator of tumor-stromal interactions

1 reference

12 December 2020

Expression of SPARC is correlated with altered morphologies in transfected F9 embryonal carcinoma cells

1 reference

12 December 2020

SPARC antagonizes the effect of basic fibroblast growth factor on the migration of bovine aortic endothelial cells

1 reference

12 December 2020

TGF-beta 1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors

1 reference

12 December 2020

Distribution of SPARC in normal and neoplastic human tissue

1 reference

12 December 2020

Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

1 reference

12 December 2020

Limited cleavage of extracellular matrix protein BM-40 by matrix metalloproteinases increases its affinity for collagens

1 reference

12 December 2020

Regulation of human monocyte matrix metalloproteinases by SPARC

1 reference

12 December 2020

Differential effects of various growth factors and cytokines on the syntheses of DNA, type I collagen, laminin, fibronectin, osteonectin/secreted protein, acidic and rich in cysteine (SPARC), and alkaline phosphatase by human pulp cells in culture

1 reference

12 December 2020

Cell cycle-dependent nuclear location of the matricellular protein SPARC: association with the nuclear matrix

1 reference

12 December 2020

Induction of TGF-beta1 by the matricellular protein SPARC in a rat model of glomerulonephritis

1 reference

12 December 2020

The fundamental role of epigenetic events in cancer

1 reference

12 December 2020

10.1016/J.CTRV.2010.12.001

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference