1,4-Dihydropyridines as calcium channel ligands and privileged structures (Q35162231)

6 August 2017

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title

1,4-Dihydropyridines as calcium channel ligands and privileged structures (English)

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6 August 2017

David J Triggle

1

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6 August 2017

publication date

1 June 2003

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Cellular and Molecular Neurobiology

6 August 2017

published in

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6 August 2017

volume

23

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6 August 2017

issue

3

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6 August 2017

page(s)

293-303

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Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor

6 August 2017

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The dihydropyridine nitrendipine modulates N-methyl-D-aspartate receptor channel function in mammalian neurons

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The dihydropyridine nitrendipine reduces N-methyl-D-aspartate (NMDA)-evoked currents of rodent cortical neurons through a direct interaction with the NMDA receptor-associated ion channel.

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Chiral resolution and stereospecificity of 6-phenyl-4-phenylethynyl- 1,4-dihydropyridines as selective A(3) adenosine receptor antagonists

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Structural basis of drug binding to L Ca2+ channels

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Calcium antagonists. History and perspective

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Isoform-specific inhibition of L-type calcium channels by dihydropyridines is independent of isoform-specific gating properties

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1,4-Dihydropyridines--a basis for developing new drugs

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The coronary vasodilator action of khellin

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Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188.

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Design and synthesis of novel alpha1a adrenoceptor-selective dihydropyridine antagonists for the treatment of benign prostatic hyperplasia

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6-phenyl-1,4-dihydropyridine derivatives as potent and selective A3 adenosine receptor antagonists

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The action of calcium channel blockers on recombinant L-type calcium channel alpha1-subunits

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The nicotinic acetylcholine receptor of the bovine chromaffin cell, a new target for dihydropyridines

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4-Alkyl-1,4-dihydropyridines derivatives as specific PAF-acether antagonists

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Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human alpha1C subunit gene

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Medicinal Chemistry: Challenges and Opportunities

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Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity

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Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.

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K-channel opening activity of dihydropyridine ZM244085: effect on 86Rb efflux and 3H-P1075 binding in urinary bladder smooth muscle

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Molecular determinants of drug binding and action on L-type calcium channels

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Dihydropyridine neuropeptide Y Y(1) receptor antagonists

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Phenylalanine in the second membrane-spanning domain of alpha 1A-adrenergic receptor determines subtype selectivity of dihydropyridine antagonists

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12 December 2020

Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes

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Ca2+ channel ligands: structure-function relationships of the 1,4-dihydropyridines

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The 1,4-dihydropyridine nucleus: a pharmacophoric template part 1. Actions at ion channels

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Structure-activity relationships of 4-(phenylethynyl)-6-phenyl-1,4-dihydropyridines as highly selective A3 adenosine receptor antagonists

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Thirty years of discovering arthropod alkaloids in amphibian skin

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Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors

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12 December 2020

State- and isoform-dependent interaction of isradipine with the alpha1C L-type calcium channel

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12 December 2020

Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1,4-dihydropyridines

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Structure and function of voltage-gated ion channels

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12 December 2020

Effects of Ca2+ channel ligands on [3H]QNB binding at m1 and m3 muscarinic receptors

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Cardiovascular effects of YM430, a 1,4-dihydropyridine derivative with beta-adrenoceptor blocking activity, in dogs and rats

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Pharmacology of H 394/84, a dihydropyridine neuropeptide Y Y(1) receptor antagonist, in vivo

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Identification of a dihydropyridine as a potent alpha1a adrenoceptor-selective antagonist that inhibits phenylephrine-induced contraction of the human prostate

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The unusual binding properties of the endothelin receptor antagonist CGS 27830 distinguishes receptor/agonist interactions

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Peptidomimetics derived from natural products

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Selectivity scale of calcium antagonists in the human cardiovascular system based on in vitro studies

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12 December 2020

Synthesis and activity of 1,4-dihydropyridine analogues of histamine H2-receptor antagonists

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12 December 2020

1,4-Dihydropyridines as antagonists of platelet activating factor. 1. Synthesis and structure-activity relationships of 2-(4-heterocyclyl)phenyl derivatives

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12 December 2020

Identifiers

DOI

10.1023/A:1023632419813

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Dimensions Publication ID

6 August 2017

1044056903

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