Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates (Q35171105)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12857950%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates (English)

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5 November 2019

4

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5 November 2019

author name string

Kathryn M Donaldson

1

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5 November 2019

Wei Li

2

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5 November 2019

Keith A Ching

3

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5 November 2019

Chih-Cheng Tsai

5

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5 November 2019

Claudio A P Joazeiro

6

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5 November 2019

language of work or name

English

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publication date

11 July 2003

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5 November 2019

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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5 November 2019

volume

100

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5 November 2019

issue

15

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5 November 2019

page(s)

8892-8897

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Vps9p CUE domain ubiquitin binding is required for efficient endocytic protein traffic

5 November 2019

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A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain

28 July 2018

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Ubiquitin signals protein trafficking via interaction with a novel ubiquitin binding domain in the membrane fusion regulator, Vps9p

28 July 2018

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28 July 2018

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Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease

28 July 2018

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The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination

28 July 2018

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The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

28 July 2018

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The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

28 July 2018

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

28 July 2018

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A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

28 July 2018

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

28 July 2018

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Structure and functional properties of the ubiquitin binding protein p62

28 July 2018

1 reference

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p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

28 July 2018

1 reference

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Preferential recruitment of ataxin-3 independent of expanded polyglutamine: an immunohistochemical study on Marinesco bodies

28 July 2018

1 reference

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Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: evidence for regulation of nerve growth factor-induced differentiation

28 July 2018

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The genomic structure and expression of MJD, the Machado-Joseph disease gene

28 July 2018

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Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies

28 July 2018

1 reference

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Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

28 July 2018

1 reference

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A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

28 July 2018

1 reference

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Ubiquitin and the molecular pathology of neurodegenerative diseases.

28 July 2018

1 reference

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UBA domains of DNA damage-inducible proteins interact with ubiquitin

28 July 2018

1 reference

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RING finger proteins: mediators of ubiquitin ligase activity

28 July 2018

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Identification and characterization of an ataxin-1-interacting protein: A1Up, a ubiquitin-like nuclear protein

28 July 2018

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Glutamine repeats and neurodegeneration

28 July 2018

1 reference

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Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro

28 July 2018

1 reference

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Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

28 July 2018

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Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

28 July 2018

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Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

28 July 2018

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Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain

28 July 2018

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The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

28 July 2018

1 reference

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CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

28 July 2018

1 reference

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Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

28 July 2018

1 reference

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Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions

27 September 2018

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Parkin and the molecular pathways of Parkinson's disease

27 September 2018

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Non-expanded polyglutamine proteins in intranuclear inclusions of hereditary ataxias--triple-labeling immunofluorescence study

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Noncovalent interaction between ubiquitin and the human DNA repair protein Mms2 is required for Ubc13-mediated polyubiquitination

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Cell biology. Protein clumps hijack cell's clearance system

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Recruitment of nonexpanded polyglutamine proteins to intranuclear aggregates in neuronal intranuclear hyaline inclusion disease

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Heterogeneous intracellular localization and expression of ataxin-3.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166409

Ubiquitin, cellular inclusions and their role in neurodegeneration

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12857950

12 December 2020

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Lactacystin, a specific inhibitor of the proteasome, induces apoptosis and activates caspase-3 in cultured cerebellar granule cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12857950

12 December 2020

inferred from PubMed ID database lookup

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12857950

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1530212100

1 reference

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5 November 2019

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release_ucb2qd3vpnbl3o6y4bp6pwhuju

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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5 November 2019

PubMed publication ID

12857950

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