Bioinformatic analysis of ciliary transition zone proteins reveals insights into the evolution of ciliopathy networks. (Q35195922)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24969356%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Bioinformatic analysis of ciliary transition zone proteins reveals insights into the evolution of ciliopathy networks (English)

1 reference

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21 March 2020

0 references

1 reference

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1

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21 March 2020

author name string

Karen S Renzaglia

series ordinal

2

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21 March 2020

Kimberley Fry

series ordinal

3

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21 March 2020

Helen R Dawe

series ordinal

4

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21 March 2020

language of work or name

English

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publication date

26 June 2014

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21 March 2020

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21 March 2020

volume

15

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21 March 2020

page(s)

531

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NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies

21 March 2020

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A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components

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Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration

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13 July 2018

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Inversin modulates the cortical actin network during mitosis

13 July 2018

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Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome

13 July 2018

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The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity.

13 July 2018

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Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects

13 July 2018

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The future of ciliary and flagellar membrane research

13 July 2018

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Molecular characterization of Joubert syndrome in Saudi Arabia

13 July 2018

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The evolution of land plant cilia

13 July 2018

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Scoring a backstage pass: mechanisms of ciliogenesis and ciliary access.

13 July 2018

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The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling

13 July 2018

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The base of the cilium: roles for transition fibres and the transition zone in ciliary formation, maintenance and compartmentalization

13 July 2018

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A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia

13 July 2018

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A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain

13 July 2018

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TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone

13 July 2018

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Accelerated Profile HMM Searches

13 July 2018

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Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development

13 July 2018

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Evolution: Tracing the origins of centrioles, cilia, and flagella

13 July 2018

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Disruption of a ciliary B9 protein complex causes Meckel syndrome

13 July 2018

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A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

13 July 2018

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Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways

13 July 2018

1 reference

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B9D1 is revealed as a novel Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis

13 July 2018

1 reference

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A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells

13 July 2018

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MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

13 July 2018

1 reference

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A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins

13 July 2018

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Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

13 July 2018

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Localization of retinitis pigmentosa 2 to cilia is regulated by Importin beta2.

13 July 2018

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Ciliopathies: an expanding disease spectrum

13 July 2018

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CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content.

13 July 2018

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Life with eight flagella: flagellar assembly and division in Giardia.

13 July 2018

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The flagellum in malarial parasites.

13 July 2018

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A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution

13 July 2018

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Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP

13 July 2018

1 reference

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Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes

13 July 2018

1 reference

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13 July 2018

1 reference

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The primary cilium: a signalling centre during vertebrate development

13 July 2018

1 reference

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Stepwise evolution of the centriole-assembly pathway.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

Reconstructing the evolutionary history of the centriole from protein components

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

BLAST+: architecture and applications

13 July 2018

1 reference

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The dawn of developmental signaling in the metazoa

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

Nephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking

13 July 2018

1 reference

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The primary cilium as a complex signaling center

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

How did the cilium evolve?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

Identification of CC2D2A as a Meckel syndrome gene adds an important piece to the ciliopathy puzzle

13 July 2018

1 reference

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Recent developments in the MAFFT multiple sequence alignment program

13 July 2018

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Recent advances in the molecular pathology, cell biology and genetics of ciliopathies

13 July 2018

1 reference

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Sensory cilia and integration of signal transduction in human health and disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

The Meckel-Gruber syndrome gene, MKS3, is mutated in Joubert syndrome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

Proteomic analysis of isolated chlamydomonas centrioles reveals orthologs of ciliary-disease genes

13 July 2018

1 reference

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The real 'kingdoms' of eukaryotes

13 July 2018

1 reference

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Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome

13 July 2018

1 reference

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More than one way to build a flagellum: comparative genomics of parasitic protozoa

13 July 2018

1 reference

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MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

13 July 2018

1 reference

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InterProScan--an integration platform for the signature-recognition methods in InterPro

13 July 2018

1 reference

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

13 July 2018

1 reference

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Ultrastructural study of early stages of asexual multiplication and microgametogony of Toxoplasma gondii in the small intestine of the cat

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092220

A TCTN2 mutation defines a novel Meckel Gruber syndrome locus.

13 July 2018

1 reference

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26 September 2018

Identifiers

DOI

10.1186/1471-2164-15-531

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24969356%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24969356%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24969356

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24969356%20AND%20SRC:MED&resulttype=core&format=json