Genes, Signals, and Lineages in Pancreas Development (Q35564797)

8 August 2017

title

Genes, signals, and lineages in pancreas development (English)

1 reference

8 August 2017

Genes, Signals, and Lineages in Pancreas Development (English)

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

23 March 2024

0 references

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

23 March 2024

2

Douglas A Melton

1 reference

8 August 2017

L. Charles Murtaugh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14570564

23 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14570564

23 March 2024

publication date

1 January 2003

1 reference

full work available at URL

8 August 2017

https://www.annualreviews.org/doi/pdf/10.1146/annurev.cellbio.19.111301.144752

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Annual Review of Cell and Developmental Biology

23 March 2024

published in

1 reference

8 August 2017

volume

19

1 reference

8 August 2017

page(s)

71-89

1 reference

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

8 August 2017

cites work

2

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

23 March 2024

3

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons.

23 March 2024

4

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Notch signalling controls pancreatic cell differentiation

23 March 2024

5

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner

23 March 2024

6

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Pancreatic cancer biology and genetics

23 March 2024

7

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia

23 March 2024

8

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

The evolving concept of a stem cell: entity or function?

23 March 2024

11

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells

23 March 2024

12

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Cytological changes in the pancreas of transgenic mice overexpressing transforming growth factor alpha

23 March 2024

13

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

A transcription factor regulatory circuit in differentiated pancreatic cells

23 March 2024

14

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

In vitro cultivation of human islets from expanded ductal tissue

23 March 2024

16

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Responses of neonatal rat islets to streptozotocin: limited B-cell regeneration and hyperglycemia

23 March 2024

17

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Transdifferentiation versus stem cell hypothesis for the regeneration of islet beta-cells in the pancreas

23 March 2024

18

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Epidermal growth factor increases undifferentiated pancreatic embryonic cells in vitro: a balance between proliferation and differentiation.

23 March 2024

19

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Polyclonal origin of pancreatic islets in aggregation mouse chimaeras

23 March 2024

21

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Sonic hedgehog is required early in pancreatic islet development

23 March 2024

23

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Ultrastructural study of pancreatic B cell regeneration in newborn rats after destruction by streptozotocin

23 March 2024

24

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Regulatory factor linked to late-onset diabetes?

23 March 2024

25

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

23 March 2024

26

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Dorsal pancreas agenesis in N-cadherin- deficient mice

23 March 2024

27

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Pancreatic duct cell cultures

23 March 2024

30

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Epitheliomesenchymal interaction in pancreatic morphogenesis

23 March 2024

32

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

23 March 2024

33

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes

23 March 2024

34

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Cell-specific transgene expression from a widely transcribed promoter using Cre/lox in mice.

23 March 2024

35

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice

23 March 2024

39

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Attenuation of FGF signalling in mouse β-cells leads to diabetes

23 March 2024

40

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Notochord repression of endodermal Sonic hedgehog permits pancreas development

23 March 2024

42

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Experimental control of pancreatic development and maintenance

23 March 2024

46

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells

23 March 2024

48

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Genetic progression in the pancreatic ducts

23 March 2024

49

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice

23 March 2024

50

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Nestin-expressing cells in the pancreatic islets of Langerhans

23 March 2024

51

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

23 March 2024

52

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

23 March 2024

53

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation

23 March 2024

54

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Control of endodermal endocrine development by Hes-1

23 March 2024

55

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Growth dynamics of pancreatic islet cell populations during fetal and neonatal development of the rat

23 March 2024

57

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

23 March 2024

58

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus

23 March 2024

60

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein

23 March 2024

61

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

23 March 2024

62

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Induction of pancreatic differentiation by signals from blood vessels.

23 March 2024

63

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Nestin expression in pancreatic stellate cells and angiogenic endothelial cells

23 March 2024

64

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

23 March 2024

65

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Regulation of the pancreatic pro-endocrine gene neurogenin3.

23 March 2024

66

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Basic helix-loop-helix genes in neural development

23 March 2024

67

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

CNS stem cells express a new class of intermediate filament protein

23 March 2024

68

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Notch signalling and the control of cell fate choices in vertebrates.

23 March 2024

69

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

23 March 2024

71

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.

23 March 2024

73

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

23 March 2024

75

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

23 March 2024

79

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Climate and management contributions to recent trends in U.S. agricultural yields

23 March 2024

80

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells

23 March 2024

81

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo

23 March 2024

82

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas

23 March 2024

85

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

23 March 2024

86

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

23 March 2024

87

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha.

23 March 2024

88

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

In-vitro differentiation of pancreatic beta-cells

23 March 2024

89

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development

23 March 2024

90

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

23 March 2024

91

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

BMP signalling regulates anteroposterior endoderm patterning in zebrafish.

23 March 2024

94

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease

23 March 2024

95

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice

23 March 2024

96

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats

23 March 2024

97

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Early Pancreas Organogenesis: Morphogenesis, Tissue Interactions, and Mass Effects

23 March 2024

99

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Gene expression cascades in pancreatic development

23 March 2024

100

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

23 March 2024

101

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.CELLBIO.19.111301.144752

23 March 2024

Identifiers

1 reference

8 August 2017

1 reference