Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling (Q35724760)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17239257%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling (English)

1 reference

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24 December 2019

1

1 reference

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24 December 2019

Kristine Hardy

2

1 reference

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24 December 2019

Lydia E Makaroff

5

1 reference

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24 December 2019

Chris Goodnow

7

1 reference

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24 December 2019

4

Susan R Wilson

1 reference

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24 December 2019

author name string

Yvonne Pittelkow

3

1 reference

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24 December 2019

Aude M Fahrer

6

1 reference

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24 December 2019

publication date

1 January 2007

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24 December 2019

1 reference

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24 December 2019

volume

8

1 reference

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24 December 2019

issue

1

1 reference

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24 December 2019

page(s)

R12

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Probe set algorithms: is there a rational best bet?

24 December 2019

cites work

1 reference

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Effects of filtering by Present call on analysis of microarray experiments

12 July 2018

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Evaluation of methods for oligonucleotide array data via quantitative real-time PCR

12 July 2018

1 reference

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Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection

12 July 2018

1 reference

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Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim.

12 July 2018

1 reference

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

12 July 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

12 July 2018

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Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues

12 July 2018

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Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas

12 July 2018

1 reference

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CD4-CD8 lineage commitment: an inside view

12 July 2018

1 reference

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Aberrant T cell differentiation in the absence of Dicer.

12 July 2018

1 reference

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Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

12 July 2018

1 reference

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Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis

12 July 2018

1 reference

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A general survey of thymocyte differentiation by transcriptional analysis of knockout mouse models

12 July 2018

1 reference

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Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein

12 July 2018

1 reference

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Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

12 July 2018

1 reference

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Nitric oxide induces BNIP3 expression that causes cell death in macrophages

12 July 2018

1 reference

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BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in non-small cell lung cancer

12 July 2018

1 reference

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Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

A role for thymic stromal lymphopoietin in CD4(+) T cell development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

The evolutionary dynamics of eukaryotic gene order

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Inferring higher functional information for RIKEN mouse full-length cDNA clones with FACTS

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

12 July 2018

1 reference

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CD47 and the 19 kDa Interacting Protein-3 (BNIP3) in T Cell Apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Aire regulates negative selection of organ-specific T cells

12 July 2018

1 reference

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Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase

12 July 2018

1 reference

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Mixed-genome microarrays reveal multiple serotype and lineage-specific differences among strains of Listeria monocytogenes

12 July 2018

1 reference

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Ly6C induces clustering of LFA-1 (CD11a/CD18) and is involved in subtype-specific adhesion of CD8 T cells

12 July 2018

1 reference

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A neural network-based similarity index for clustering DNA microarray data

12 July 2018

1 reference

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Heterologous expression and characterization of mouse spermine oxidase

12 July 2018

1 reference

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Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB.

12 July 2018

1 reference

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Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival

12 July 2018

1 reference

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Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.

12 July 2018

1 reference

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Positive and negative selection of T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Projection of an immunological self shadow within the thymus by the aire protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Identification and characterization of a novel murine multigene family containing a PHD-finger-like motif

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Combining mouse congenic strains and microarray gene expression analyses to study a complex trait: the NOD model of type 1 diabetes

12 July 2018

1 reference

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Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments

12 July 2018

1 reference

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Transgenic rescue implicates beta2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

12 July 2018

1 reference

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Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

12 July 2018

1 reference

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Human Vam6p promotes lysosome clustering and fusion in vivo

12 July 2018

1 reference

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Neuroendocrine secretory protein 7B2: structure, expression and functions

12 July 2018

1 reference

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Computational analysis of microarray data

12 July 2018

1 reference

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The tripartite motif family identifies cell compartments

12 July 2018

1 reference

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Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

12 July 2018

1 reference

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Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate

12 July 2018

1 reference

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Functional genomics reveals a family of eukaryotic oxidation protection genes

12 July 2018

1 reference

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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

12 July 2018

1 reference

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A monoclonal antibody to the rat Crry/p65 antigen, a complement regulatory membrane protein, stimulates adhesion and proliferation of thymocytes

12 July 2018

1 reference

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Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice

12 July 2018

1 reference

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BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

12 July 2018

1 reference

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Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Specific regulation of fos family transcription factors in thymocytes at two developmental checkpoints

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

A B-cell-specific DNA recombination complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Identification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYN

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

FRAG1, a gene that potently activates fibroblast growth factor receptor by C-terminal fusion through chromosomal rearrangement

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Molecular cloning of the cDNAs for the four subunits of mouse DNA polymerase alpha-primase complex and their gene expression during cell proliferation and the cell cycle.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Reticulocalbin, a novel endoplasmic reticulum resident Ca(2+)-binding protein with multiple EF-hand motifs and a carboxyl-terminal HDEL sequence

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Two-hybrid system screen with the small GTP-binding protein Rab6. Identification of a novel mouse GDP dissociation inhibitor isoform and two other potential partners of Rab6

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Analysis of transcription factor expression during discrete stages of postnatal thymocyte differentiation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Expression of membrane and nuclear melatonin receptor mRNA and protein in the mouse immune system

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Role of GRP58 in mitomycin C-induced DNA cross-linking

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Gene expression analysis of thymocyte selection in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Characterization of transcriptional regulation during negative selection in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

The osmoprotective function of the NFAT5 transcription factor in T cell development and activation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

The p58 subunit of human DNA primase is important for primer initiation, elongation, and counting

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Immunological adjuvants promote activated T cell survival via induction of Bcl-3.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Role of the forkhead transcription family member, FKHR, in thymocyte differentiation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Regulated expression of gp130 and IL-6 receptor alpha chain in T cell maturation and activation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

CTLA-4-/- mice display T cell-apoptosis resistance resembling that ascribed to autoimmune-prone non-obese diabetic (NOD) mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

TRANCE, a TNF family member, is differentially expressed on T cell subsets and induces cytokine production in dendritic cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1839132

Antigen-specific and nonspecific deletion of immature cortical thymocytes caused by antigen injection

25 September 2018

1 reference

12 December 2020

A T cell activation antigen, Ly6C, induced on CD4+ Th1 cells mediates an inhibitory signal for secretion of IL-2 and proliferation in peripheral immune responses

1 reference

12 December 2020

A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation

1 reference

12 December 2020

Thymocyte stimulation by anti-TCR-beta, but not by anti-TCR-alpha, leads to induction of developmental transcription program

1 reference

12 December 2020

Hypoxia induces the expression of the pro-apoptotic gene BNIP3

1 reference

12 December 2020

A defect in central tolerance in NOD mice

1 reference

12 December 2020

Defective central tolerance induction in NOD mice: genomics and genetics

1 reference

12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

12 December 2020

The regulated expression of a diverse set of genes during thymocyte positive selection in vivo

1 reference

12 December 2020

T cell tolerance by clonal elimination in the thymus

1 reference

12 December 2020

Identifiers

DOI

10.1186/GB-2007-8-1-R12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17239257%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17239257%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

PubMed publication ID

17239257

1 reference