Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition (Q35889116)

10 August 2017

Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition (English)

1 reference

10 August 2017

1 reference

Justin T Mohr

2

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Ku-lung Hsu

object named as

Ku-Lung Hsu

5

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Benjamin Cravatt

10

object named as

Benjamin F Cravatt

1 reference

10 August 2017

Andrea M Zuhl

1

1 reference

10 August 2017

Daniel A Bachovchin

3

1 reference

10 August 2017

Sherry Niessen

4

1 reference

10 August 2017

Jacob M Berlin

6

1 reference

10 August 2017

Maximilian Dochnahl

7

1 reference

10 August 2017

María P López-Alberca

8

1 reference

10 August 2017

Gregory C Fu

9

1 reference

10 August 2017

language of work or name

English

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publication date

8 March 2012

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Journal of the American Chemical Society

10 August 2017

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10 August 2017

134

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10 August 2017

11

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10 August 2017

5068-5071

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The pharmacological landscape and therapeutic potential of serine hydrolases

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

The metabolic serine hydrolases and their functions in mammalian physiology and disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Academic cross-fertilization by public screening yields a remarkable class of protein phosphatase methylesterase-1 inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Acylating drugs: redesigning natural covalent inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

A review of HCV protease inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Catalytic asymmetric cycloaddition of ketenes and nitroso compounds: enantioselective synthesis of alpha-hydroxycarboxylic acid derivatives

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Enantioselective nucleophilic catalysis: the synthesis of aza-beta-lactams through [2+2] cycloadditions of ketenes with azo compounds

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Activity-based protein profiling: applications to biomarker discovery, in vivo imaging and drug discovery

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

A streamlined platform for high-content functional proteomics of primary human specimens

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326416

Beta-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22400490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA300799T

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22400490

1 reference