Diagnosing prion diseases: needs, challenges and hopes (Q35892062)

11 August 2017

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title

Diagnosing prion diseases: needs, challenges and hopes (English)

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11 August 2017

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Claudio Soto

1

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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Nature Reviews Microbiology

11 August 2017

published in

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11 August 2017

volume

2

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11 August 2017

issue

10

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11 August 2017

page(s)

809-819

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Rapid test for the preclinical postmortem diagnosis of BSE in central nervous system tissue

11 August 2017

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Cyclic amplification of protein misfolding: application to prion-related disorders and beyond

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Synthetic mammalian prions

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Blood infectivity and the prospects for a diagnostic screening test in Creutzfeldt-Jakob disease

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Therapeutic approaches to prion diseases.

31 March 2020

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Rapid diagnosis of scrapie in the mouse

31 March 2020

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Mouse models of prion disease transmission

31 March 2020

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Early detection of PrPres in BSE-infected bovine PrP transgenic mice

31 March 2020

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Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy

31 March 2020

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Preclinical test for prion diseases

31 March 2020

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Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease

31 March 2020

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Prevalence of lymphoreticular prion protein accumulation in UK tissue samples.

31 March 2020

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Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease

31 March 2020

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Detection of pathologic prion protein in the olfactory epithelium in sporadic Creutzfeldt-Jakob disease

31 March 2020

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A protease-resistant prion protein isoform is present in urine of animals and humans affected with prion diseases

31 March 2020

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A pitfall in diagnosis of human prion diseases using detection of protease-resistant prion protein in urine. Contamination with bacterial outer membrane proteins

31 March 2020

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Antigenic features of prion proteins of sheep and of other mammalian species

31 March 2020

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New insight into abnormal prion protein using monoclonal antibodies

31 March 2020

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Immunodiagnosis of prion disease.

31 March 2020

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Prion (PrPSc)-specific epitope defined by a monoclonal antibody

31 March 2020

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Monoclonal antibodies specific for the native, disease-associated isoform of the prion protein

31 March 2020

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A prion protein epitope selective for the pathologically misfolded conformation

31 March 2020

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Monoclonal antibody against a peptide of human prion protein discriminates between Creutzfeldt-Jacob's disease-affected and normal brain tissue

31 March 2020

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Antibody to DNA detects scrapie but not normal prion protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Detection and discrimination of PrPSc by multi-spectral ultraviolet fluorescence

31 March 2020

1 reference

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Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Antemortem identification of bovine spongiform encephalopathy from serum using infrared spectroscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Molecular changes of preclinical scrapie can be detected by infrared spectroscopy.

31 March 2020

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A diagnostic test for scrapie-infected sheep using a capillary electrophoresis immunoassay with fluorescent-labeled peptides

31 March 2020

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Use of capillary electrophoresis and fluorescent labeled peptides to detect the abnormal prion protein in the blood of animals that are infected with a transmissible spongiform encephalopathy

31 March 2020

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Analysis of the performance of antibody capture methods using fluorescent peptides with capillary zone electrophoresis with laser-induced fluorescence

31 March 2020

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Failure of immunocompetitive capillary electrophoresis assay to detect disease-specific prion protein in buffy coat from humans and chimpanzees with Creutzfeldt-Jakob disease

31 March 2020

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Binding of disease-associated prion protein to plasminogen.

31 March 2020

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Plasminogen binds to disease-associated prion protein of multiple species

31 March 2020

1 reference

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The fate of the prion protein in the prion/plasminogen complex

31 March 2020

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The binding of prion proteins to serum components is affected by detergent extraction conditions

31 March 2020

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Endogenous viral complexes with long RNA cosediment with the agent of Creutzfeldt-Jakob disease

31 March 2020

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RNA molecules stimulate prion protein conversion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

The prion protein has RNA binding and chaperoning properties characteristic of nucleocapsid protein NCP7 of HIV-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Prion-protein-specific aptamer reduces PrPSc formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Structural determinants of conformationally selective, prion-binding aptamers.

31 March 2020

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A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions

31 March 2020

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Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

31 March 2020

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Cultured cell sublines highly susceptible to prion infection

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Susceptibility of common fibroblast cell lines to transmissible spongiform encephalopathy agents

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO1003

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Creutzfeldt-Jakob disease: blood infectivity and screening tests

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

The distribution of infectivity in blood components and plasma derivatives in experimental models of transmissible spongiform encephalopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Scrapie infectivity in hamster blood is not associated with platelets.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1003

Protein misfolding and disease; protein refolding and therapy

31 March 2020

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31 March 2020

Conformational disease

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31 March 2020

Identifiers

DOI

10.1038/NRMICRO1003

1 reference

11 August 2017

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