The role of the unfolded protein response in tumour development: friend or foe? (Q35968425)

11 August 2017

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title

The role of the unfolded protein response in tumour development: friend or foe? (English)

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11 August 2017

Yanjun Ma

1

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11 August 2017

Linda M Hendershot

series ordinal

2

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11 August 2017

language of work or name

English

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publication date

1 December 2004

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11 August 2017

published in

Nature Reviews Cancer

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11 August 2017

volume

4

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11 August 2017

issue

12

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11 August 2017

page(s)

966-977

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Mammalian stress response: induction of the glucose-regulated protein family

11 August 2017

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Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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PERK mediates cell-cycle exit during the mammalian unfolded protein response

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Regulation of apoptosis by endoplasmic reticulum pathways.

31 March 2020

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Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

31 March 2020

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31 March 2020

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Depletion of topoisomerase II in isolated nuclei during a glucose-regulated stress response

31 March 2020

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Down-regulation of topoisomerase II alpha is caused by up-regulation of GRP78.

31 March 2020

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Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

31 March 2020

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Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

31 March 2020

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Cloning of mammalian Ire1 reveals diversity in the ER stress responses

31 March 2020

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

31 March 2020

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

31 March 2020

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Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

31 March 2020

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Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress

31 March 2020

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Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response

31 March 2020

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Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

31 March 2020

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ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

31 March 2020

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

31 March 2020

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

31 March 2020

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Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

31 March 2020

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

31 March 2020

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

31 March 2020

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JAB1 participates in unfolded protein responses by association and dissociation with IRE1

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC1505

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Dimensions Publication ID

11 August 2017

1026944005

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