Genetic and epigenetic features in radiation sensitivity Part I: cell signalling in radiation response (Q36013284)

11 August 2017

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title

Genetic and epigenetic features in radiation sensitivity Part I: cell signalling in radiation response (English)

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11 August 2017

7

Edgardo D Carosella

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11 August 2017

Michel H Bourguignon

1

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11 August 2017

Pablo A Gisone

2

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11 August 2017

Maria R Perez

3

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11 August 2017

Severino Michelin

4

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11 August 2017

Diana Dubner

5

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11 August 2017

Marina Di Giorgio

6

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11 August 2017

publication date

1 February 2005

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European Journal of Nuclear Medicine and Molecular Imaging

11 August 2017

published in

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11 August 2017

volume

32

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11 August 2017

issue

2

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11 August 2017

page(s)

229-246

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DNA-PK: at the cross-roads of biochemistry and genetics

11 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Nijmegen Breakage Syndrome Cells Fail To Induce the p53-Mediated DNA Damage Response following Exposure to Ionizing Radiation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Activation of caspases in p53-induced transactivation-independent apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Fragments of ATM which have dominant-negative or complementing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Delayed chromosomal instability induced by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Ionizing radiation and genetic risks. III. Nature of spontaneous and radiation-induced mutations in mammalian in vitro systems and mechanisms of induction of mutations by radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Ionizing radiation and genetic risks. II. Nature of radiation-induced mutations in experimental mammalian in vivo systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Chromosomal aberrations: formation, identification and distribution

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00259-004-1730-7

Mechanisms of human DNA repair: an update

21 January 2018

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12 December 2020

Potential clinical impact of normal-tissue intrinsic radiosensitivity testing

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12 December 2020

Prediction of tumor radiosensitivity in rectal carcinoma based on p53 and Ku70 expression

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12 December 2020

Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine

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12 December 2020

Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins

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12 December 2020

Farnesyltransferase inhibitors as radiation sensitizers

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12 December 2020

DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology.

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12 December 2020

Radioresistance in murine solid tumors induced by interleukin-1

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12 December 2020

Comparison between normal tissue reactions and local tumor control in head and neck cancer patients treated by definitive radiotherapy

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12 December 2020

Prognostic factors for acute and late skin reactions in radiotherapy patients

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12 December 2020

Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta-converting enzyme-mediated apoptosis

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12 December 2020

Radiation-induced genomic instability and persisting oxidative stress in primary bone marrow cultures.

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12 December 2020

Genomic instability induced by ionizing radiation.

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12 December 2020

The RAS signal transduction pathway and its role in radiation sensitivity

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12 December 2020

Reactive oxygen species in cell signaling

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12 December 2020

Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine responses to IL-1 and tumor necrosis factor

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12 December 2020

Nitric oxide-mediated signaling in the bystander response of individually targeted glioma cells.

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12 December 2020

The ras oncogenes increase the intrinsic resistance of NIH 3T3 cells to ionizing radiation

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12 December 2020

Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation?

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12 December 2020

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

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12 December 2020

Human exonuclease I is required for 5' and 3' mismatch repair

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12 December 2020

Prediction of normal-tissue tolerance to radiotherapy from in-vitro cellular radiation sensitivity

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12 December 2020

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

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12 December 2020

Chromosomal instability and alterations of telomeric repeats in irradiated human fibroblasts.

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12 December 2020

Radiation-induced genomic instability: radiation quality and dose response

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12 December 2020

High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation

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12 December 2020

Dominant oncogenes, tumor suppressors, and radiosensitivity.

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12 December 2020

Purification and characterization of human DNA damage checkpoint Rad complexes

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12 December 2020

Genomic instability induced by high and low LET ionizing radiation.

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12 December 2020

Bystander effects: a concept in need of clarification

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12 December 2020

The p53-mediated DNA damage response to ionizing radiation in fibroblasts from ataxia-without-telangiectasia patients

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12 December 2020

Analysis by alkaline comet assay of cancer patients with severe reactions to radiotherapy: defective rejoining of radioinduced DNA strand breaks in lymphocytes of breast cancer patients

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12 December 2020

Recombination involving interstitial telomere repeat-like sequences promotes chromosomal instability in Chinese hamster cells

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12 December 2020

The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle

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12 December 2020

DNA damage and repair: consequences on dose-responses

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12 December 2020

Genetic susceptibility to radiation effects: possible implication for medical ionising radiation exposures

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12 December 2020

Production of delayed death and neoplastic transformation in CGL1 cells by radiation-induced bystander effects

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12 December 2020

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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12 December 2020

Radiation-induced DNA damage and repair in lymphocytes from breast cancer patients and their correlation with acute skin reactions to radiotherapy

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12 December 2020

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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12 December 2020

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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12 December 2020

The relationship between cellular radiation sensitivity and tissue response may provide the basis for individualising radiotherapy schedules

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12 December 2020

Acute induction of inflammatory cytokine expression after gamma-irradiation in the rat: effect of an NF-kappaB inhibitor

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12 December 2020

Dual function for poly(ADP-ribose) synthesis in response to DNA strand breakage

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12 December 2020

Interleukin-1 beta suppresses apoptosis in CD34 positive bone marrow cells through activation of the type I IL-1 receptor

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12 December 2020

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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12 December 2020

The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase

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12 December 2020

Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review

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12 December 2020

Radiation-Induced Cellular Reproductive Death and Chromosome Aberrations

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12 December 2020

Overexpression of c-Myc alters G(1)/S arrest following ionizing radiation

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12 December 2020

The Induction of Liver Tumors by 239 Pu Citrate or 239 PuO 2 Particles in the Chinese Hamster

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12 December 2020

X radiation causes a persistent induction of reactive oxygen species and a delayed reinduction of TP53 in normal human diploid fibroblasts

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12 December 2020

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

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12 December 2020

Sensing and repairing DNA double-strand breaks

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12 December 2020

Apoptosis by death factor

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12 December 2020

Synergistic effect of the v-myc oncogene with H-ras on radioresistance.

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12 December 2020

Persistent oxidative stress after ionizing radiation is involved in inherited radiosensitivity

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12 December 2020

ATM haplotypes and cellular response to DNA damage: association with breast cancer risk and clinical radiosensitivity

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12 December 2020

p53, the cellular gatekeeper for growth and division

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12 December 2020

A charged-particle microbeam: I. Development of an experimental system for targeting cells individually with counted particles

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12 December 2020

The Columbia University single-ion microbeam

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12 December 2020

Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis

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12 December 2020

The DNA damage response: putting checkpoints in perspective

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12 December 2020

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

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12 December 2020

Cellular and molecular mechanisms of radioresistance.

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12 December 2020

Genomic instability in human lymphoid cells exposed to 1 GeV/amu Fe ions

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12 December 2020

A novel Rad24 checkpoint protein complex closely related to replication factor C.

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12 December 2020

Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells

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12 December 2020

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

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12 December 2020

Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process

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12 December 2020

Cell cycle and genetic background dependence of the effect of loss of BRCA2 on ionizing radiation sensitivity

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12 December 2020

In search of the tumour-suppressor functions of BRCA1 and BRCA2

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12 December 2020

CDK inhibitors: positive and negative regulators of G1-phase progression

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12 December 2020

ATM-dependent and -independent gene expression changes in response to oxidative stress, gamma irradiation, and UV irradiation.

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12 December 2020

Activation of Raf by ionizing radiation

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12 December 2020

Identification and purification of two distinct complexes containing the five RAD51 paralogs

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12 December 2020

Tissue-specific induction of p53 targets in vivo.

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12 December 2020

X-RAY-INDUCED HERITABLE DAMAGE (SMALL-COLONY FORMATION) IN CULTURED MAMMALIAN CELLS

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12 December 2020

p53 has a direct apoptogenic role at the mitochondria

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12 December 2020

DNA double strand break repair and chromosomal translocation: lessons from animal models

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12 December 2020

Free radicals generated by ionizing radiation signal nuclear translocation of p53.

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12 December 2020

Delayed reproductive death as a dominant phenotype in cell clones surviving X-irradiation

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12 December 2020

DNA-dependent protein kinase

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12 December 2020

p21(WAF1/Cip1): more than a break to the cell cycle?

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12 December 2020

Telomeric sequences, radiation sensitivity and genomic instability

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12 December 2020

Sequential chromosome aberration analysis following radiotherapy - no evidence for enhanced genomic instability

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12 December 2020

[Tumor and individual radiosensitivity. An introduction]

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12 December 2020

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs

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12 December 2020

ATM and ATR: networking cellular responses to DNA damage

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12 December 2020

p53-dependent pathways of apoptosis

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12 December 2020

Bystander and delayed effects after fractionated radiation exposure

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12 December 2020

Studies on radiosensitivity from an epidemiological point of view - overview of methods and results

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12 December 2020

Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability

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12 December 2020

A cellular survival switch: poly(ADP-ribosyl)ation stimulates DNA repair and silences transcription

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12 December 2020

The DNA-activated protein kinase -- DNA-PK

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12 December 2020

Direct evidence for a bystander effect of ionizing radiation in primary human fibroblasts

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12 December 2020

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

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12 December 2020

Chemical biology of nitric oxide: regulation and protective and toxic mechanisms.

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12 December 2020

Chromosomal instability in acute myelocytic leukemia and myelodysplastic syndrome patients among atomic bomb survivors

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12 December 2020

The radiation-induced bystander effect for clonogenic survival

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12 December 2020

Expression of lethal mutations in progeny of irradiated mammalian cells

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12 December 2020

Heterogeneity of DNA repair at the gene level

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12 December 2020

Role for ATM in DNA damage-induced phosphorylation of BRCA1

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12 December 2020

The Mre11 complex and ATM: collaborating to navigate S phase

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12 December 2020

A role for ATR in the DNA damage-induced phosphorylation of p53

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12 December 2020

Genomic instability in Chinese hamster cells after exposure to X rays or alpha particles of different mean linear energy transfer

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12 December 2020

Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: II. Radiation-Induced Genomic Instability and Bystander EffectsIn Vivo,Clastogenic Factors and Transgenerational Effects

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12 December 2020

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

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12 December 2020

Chromosome aberrations in radiation workers with internal deposits of plutonium

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12 December 2020

Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: I. Radiation-Induced Genomic Instability and Bystander EffectsIn Vitro

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12 December 2020

Phosphorylation of histone H2AX as a measure of radiosensitivity

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12 December 2020

Toward maintaining the genome: DNA damage and replication checkpoints

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12 December 2020

Do DNA double-strand breaks induced by Alu I lead to development of novel aberrations in the second and third post-treatment mitoses?

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12 December 2020

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

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12 December 2020

Sensor-less checkpoint activation?

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12 December 2020

p53: puzzle and paradigm

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12 December 2020

Redox regulation of cellular signalling

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12 December 2020

Alpha-irradiation-induced G2 delay: a period of cell recovery

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12 December 2020

DNA damage and repair

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12 December 2020

Epidermal growth factor receptor and its inhibition in radiotherapy:in vivofindings

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12 December 2020

Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast

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12 December 2020

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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12 December 2020

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

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12 December 2020

Perpetuating radiation-induced chromosomal instability

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12 December 2020

The bystander effect in radiation oncogenesis: I. Transformation in C3H 10T1/2 cells in vitro can be initiated in the unirradiated neighbors of irradiated cells

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12 December 2020

Hypophosphorylation of Mdm2 augments p53 stability

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12 December 2020

Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation

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12 December 2020

Poly ADP-ribosylation: a DNA break signal mechanism

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12 December 2020

STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells

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12 December 2020

DNA damage checkpoint control in cells exposed to ionizing radiation

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12 December 2020

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

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12 December 2020

Synergy of IL-1 and stem cell factor in radioprotection of mice is associated with IL-1 up-regulation of mRNA and protein expression for c-kit on bone marrow cells.

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12 December 2020

Expression of Ku80 in cervical cancer correlates with response to radiotherapy and survival.

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12 December 2020

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

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12 December 2020

Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment

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12 December 2020

Induction of radioresistance by a nitric oxide-mediated bystander effect

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12 December 2020

Double-strand-break-induced homologous recombination in mammalian cells

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12 December 2020

Delayed Reproductive Death in X-irradiated Chinese Hamster Ovary Cells

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12 December 2020

Radiation-induced genomic instability: delayed mutagenic and cytogenetic effects of X rays and alpha particles.

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12 December 2020

Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy

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12 December 2020

P53 and radiation responses

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12 December 2020

Induction of a bystander mutagenic effect of alpha particles in mammalian cells

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12 December 2020

Chromosomal translocations in human cancer.

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12 December 2020

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

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12 December 2020

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

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12 December 2020

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12 December 2020

Telomeres and their possible role in chromosome stabilization

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12 December 2020

Repair of radiation damage to DNA.

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12 December 2020

Radiation and ceramide-induced apoptosis

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12 December 2020

Radiogenetic therapy: strategies to overcome tumor resistance.

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12 December 2020

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

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12 December 2020

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.

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12 December 2020

Three distinct signalling responses by murine fibroblasts to genotoxic stress

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12 December 2020

Failla Memorial Lecture. Changing views of cellular radiosensitivity

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12 December 2020

A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation.

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12 December 2020

X-ray induction of methotrexate resistance due to dhfr gene amplification

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12 December 2020

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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12 December 2020

Critical target and dose and dose-rate responses for the induction of chromosomal instability by ionizing radiation.

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12 December 2020

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

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12 December 2020

Mismatch repair defects in cancer

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12 December 2020

Dual roles of ATM in the cellular response to radiation and in cell growth control.

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12 December 2020

Biological consequences of free radical-damaged DNA bases.

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12 December 2020

Localization of an ataxia-telangiectasia gene to chromosome 11q22-23.

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12 December 2020

Genome maintenance mechanisms for preventing cancer

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12 December 2020

Spectrum of X-ray-induced mutations in the human hprt gene

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12 December 2020

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

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12 December 2020

10.1007/S00259-004-1730-7

Identifiers

DOI

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11 August 2017

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