Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation (Q36069797)

12 August 2017

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title

Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation (English)

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12 August 2017

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4

Kevan Herold

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12 August 2017

6

Ann Marie Schmidt

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12 August 2017

author name string

Ravichandran Ramasamy

1

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12 August 2017

Susan J Vannucci

2

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12 August 2017

Shirley Shi Du Yan

3

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12 August 2017

Shi Fang Yan

5

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12 August 2017

publication date

10 March 2005

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12 August 2017

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12 August 2017

volume

15

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12 August 2017

issue

7

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12 August 2017

page(s)

16R-28R

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N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins

12 August 2017

cites work

1 reference

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The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation

21 January 2018

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High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

21 January 2018

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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

21 January 2018

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S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE)

21 January 2018

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Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

21 January 2018

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Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine

21 January 2018

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Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia

21 January 2018

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The role of AGEs in aging: causation or correlation

21 January 2018

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The Maillard hypothesis on aging: time to focus on DNA.

21 January 2018

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Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily

21 January 2018

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Randomized trial of an inhibitor of formation of advanced glycation end products in diabetic nephropathy

21 January 2018

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Glycation products and the pathogenesis of diabetic complications

21 January 2018

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RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

21 January 2018

1 reference

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RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB

21 January 2018

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The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment

21 January 2018

1 reference

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Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products

21 January 2018

1 reference

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The receptor RAGE as a progression factor amplifying arachidonate-dependent inflammatory and proteolytic response in human atherosclerotic plaques: role of glycemic control

21 January 2018

1 reference

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Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease

21 January 2018

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A redox-triggered ras-effector interaction. Recruitment of phosphatidylinositol 3'-kinase to Ras by redox stress.

21 January 2018

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S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

21 January 2018

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Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

21 January 2018

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N epsilon-carboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease.

21 January 2018

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Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection

21 January 2018

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Advanced glycoxidation end products in commonly consumed foods

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice.

21 January 2018

1 reference

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Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

21 January 2018

1 reference

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Plasma 3-deoxyglucosone elevation in chronic renal failure is associated with increased aldose reductase in erythrocytes

21 January 2018

1 reference

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Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

21 January 2018

1 reference

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RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response

21 January 2018

1 reference

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Stroke and the risk of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

S100 proteins in Corpora amylacea from normal human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

N (epsilon)-(carboxymethyl)lysine protein adduct is a major immunological epitope in proteins modified with advanced glycation end products of the Maillard reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Increased risk of type 2 diabetes in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase inhibitor administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain

21 January 2018

1 reference

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Diabetes and cardiovascular disease. The Framingham study

21 January 2018

1 reference

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Improved arterial compliance by a novel advanced glycation end-product crosslink breaker

21 January 2018

1 reference

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Glycation-induced inactivation of NADP(+)-dependent isocitrate dehydrogenase: implications for diabetes and aging

21 January 2018

1 reference

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The biology of senescence: potential for prevention of disease

21 January 2018

1 reference

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N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Relation between serum 3-deoxyglucosone and development of diabetic microangiopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Characterization and functional analysis of the promoter of RAGE, the receptor for advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Hyperinsulinemia and risk of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Evidence for non-enzymatic glycosylation in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyl

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

How does glucose generate oxidative stress in peripheral nerve?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Role of advanced glycation end products in aging collagen. A scanning force microscope study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Age-dependent accumulation of advanced glycation end-products in adult Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Beta 2-microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Evidence of preferential protein targets for age-related modifications in peripheral blood lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Advanced glycation end products modulate the maturation and function of peripheral blood dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Central role of RAGE-dependent neointimal expansion in arterial restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

The S100 family of EF-hand calcium-binding proteins: functions and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Fructose-mediated non-enzymatic glycation: sweet coupling or bad modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of dia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Regulation of human mononuclear phagocyte migration by cell surface-binding proteins for advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Age associated changes of AGE-receptor expression: RAGE upregulation is associated with human heart dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Crosslink breakers: a new approach to cardiovascular therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Neurotoxicity of advanced glycation end-products for cultured cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

In vitro formation of N(epsilon)-(carboxymethyl)lysine and imidazolones under conditions similar to continuous ambulatory peritoneal dialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Protein glycation, diabetes, and aging

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Restriction of dietary glycotoxins reduces excessive advanced glycation end products in renal failure patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Binding of receptor for advanced glycation end products (RAGE) ligands is not sufficient to induce inflammatory signals: lack of activity of endotoxin-free albumin-derived advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy

21 January 2018

1 reference

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HMG-1 as a late mediator of endotoxin lethality in mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Protein glycation: a firm link to endothelial cell dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Glycation-induced inactivation and loss of antigenicity of catalase and superoxide dismutase

21 January 2018

1 reference

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Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system

21 January 2018

1 reference

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Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

The S100 protein family: history, function, and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FGLYCOB%2FCWI053

21 January 2018

Identifiers

DOI

10.1093/GLYCOB/CWI053

1 reference

release_ftyzyyxklndc7gj3qaetbboaoy

12 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ftyzyyxklndc7gj3qaetbboaoy

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference