Biomarkers for amyotrophic lateral sclerosis (Q36481118)

14 August 2017

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title

Biomarkers for amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

14 August 2017

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3

Rima Kaddurah-Daouk

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Merit E Cudkowicz

series ordinal

2

object named as

Merit Cudkowicz

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14 August 2017

Robert Bowser

1

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14 August 2017

publication date

1 May 2006

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Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

14 August 2017

published in

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14 August 2017

volume

6

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14 August 2017

issue

3

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14 August 2017

page(s)

387-398

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

14 August 2017

cites work

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https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The basic aspects of therapeutics in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Biomarkers and surrogate endpoints: preferred definitions and conceptual framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Biomarker identification in neurologic diseases: improving diagnostics and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Biomarkers and surrogate markers: an FDA perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Molecular biomarkers in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Measures and markers in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Clinical biomarkers in drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Guidelines in motor neurone disease (MND)/amyotrophic lateral sclerosis (ALS) - from diagnosis to patient care

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Diagnostic dilemmas in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Challenges in breast cancer clinical trial design in the postgenomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Biological surrogate end-points in cancer trials: potential uses, benefits and pitfalls

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Genetic epidemiology of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Complex genetics of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Mutant dynactin in motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Functional outcome measures as clinical trial endpoints in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Neurophysiological measures in amyotrophic lateral sclerosis: markers of progression in clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Motor unit number estimate-based rates of progression of ALS predict patient survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The use of statistical MUNE in a multicenter clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Clinical trials in ALS: a review of the role of clinical and neurophysiological measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The ALSFRSr predicts survival time in an ALS clinic population

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A prospective, randomized, placebo‐controlled evaluation of corticoneuronal response to intrathecal BDNF therapy in ALS using magnetic resonance spectroscopy: feasibility and results

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Reduced NAA in motor and non-motor brain regions in amyotrophic lateral sclerosis: a cross-sectional and longitudinal study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Amyotrophic lateral sclerosis: the search for a spectroscopic marker of upper motoneuron involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Effect of creatine supplementation on metabolite levels in ALS motor cortices

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Analysis of immune complexes of cerebrospinal fluid by two-dimensional gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Superoxide dismutase in CSF from amyotrophic lateral sclerosis patients with and without CuZn-superoxide dismutase mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Amyotrophic lateral sclerosis: disease stage related changes of tau protein and S100 beta in cerebrospinal fluid and creatine kinase in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Pigment epithelium-derived factor is elevated in CSF of patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Expression of vascular endothelial growth factor and its receptors in the central nervous system in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Altered expression of the glutamate transporter EAAT2b in neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Inflammatory processes in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Increased concentration of C4d complement protein in CSF in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Serum and CSF immunological findings in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Passive transfer of purified IgG from patients with amyotrophic lateral sclerosis to mice results in degeneration of motor neurons accompanied by Ca 2+ enhancement

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Molecular signature of late-stage human ALS revealed by expression profiling of postmortem spinal cord gray matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Parallel analysis of transcript and metabolic profiles: a new approach in systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Metabolomics by numbers: acquiring and understanding global metabolite data

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Serotoninergic system in dementia of the Alzheimer type. Abnormal forms of 5-hydroxytryptophan and serotonin in cerebrospinal fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Metabolomic analysis and signatures in motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Metabolomics and systems biology: making sense of the soup

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The human plasma proteome: history, character, and diagnostic prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Proteomic analysis of cerebrospinal fluid from multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Proteomic profiling and neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses, and nitric oxide synthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

CSF biomarkers for Alzheimer's disease: use in early diagnosis and evaluation of drug treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Cerebrospinal fluid protein patterns in neurodegenerative disease revealed by liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Proteomic profiling of cerebrospinal fluid identifies biomarkers for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Inactivation of the 7B2 inhibitory CT peptide depends on a functional furin cleavage site

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The relationship between Bunina bodies, skein-like inclusions and neuronal loss in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The evolution of transthyretin synthesis in the choroid plexus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Evolution of the thyroid hormone-binding protein, transthyretin

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

The transthyretin-retinol-binding protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Cerebrospinal fluid transthyretin: aging and late onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Human cerebrospinal fluid peptidomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Linkage of a commoner form of recessive amyotrophic lateral sclerosis to chromosome 15q15-q22 markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Identification of two novel loci for dominantly inherited familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A novel locus for late onset amyotrophic lateral sclerosis/motor neurone disease variant at 20q13

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Quantitating progression in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Inter-evaluator reliability of the ALS Functional Rating Scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Proteomic profiling from human samples: the body fluid alternative

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Quantitative motor assessment in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Prognostic indicators of survival in ALS. ALS CNTF Treatment Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Comparison of maximal voluntary isometric contraction and Drachman's hand-held dynamometry in evaluating patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

A comparison of muscle strength testing techniques in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Single motor unit variability with threshold stimulation in patients with amyotrophic lateral sclerosis and normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Nogo expression in muscle correlates with amyotrophic lateral sclerosis severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Tau protein concentrations in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Increased oxidative damage to DNA in ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Pan-neuronal mRNA expression of the secretory polypeptide 7B2

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Matrix metalloproteinase-9 is elevated in serum of patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

Evaluation of antioxidants, protein, and lipid oxidation products in blood from sporadic amyotrophic lateral sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737159.6.3.387

21 January 2018

Identifiers

DOI

10.1586/14737159.6.3.387

1 reference

14 August 2017

1 reference