Neuronal polarity: from extracellular signals to intracellular mechanisms (Q36740342)

16 August 2017

1 reference

title

Neuronal polarity: from extracellular signals to intracellular mechanisms (English)

1 reference

16 August 2017

Nariko Arimura

1

1 reference

16 August 2017

Kozo Kaibuchi

series ordinal

2

1 reference

16 August 2017

language of work or name

English

0 references

publication date

1 March 2007

1 reference

Nature Reviews Neuroscience

16 August 2017

published in

1 reference

16 August 2017

volume

8

1 reference

16 August 2017

issue

3

1 reference

16 August 2017

page(s)

194-205

1 reference

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

16 August 2017

cites work

1 reference

Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction

21 January 2018

1 reference

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

21 January 2018

1 reference

Axon specification in hippocampal neurons.

21 January 2018

1 reference

31 March 2020

1 reference

Structure and function of dendritic spines

31 March 2020

1 reference

The establishment of polarity by hippocampal neurons in culture

31 March 2020

1 reference

Growth cones are not required for initial establishment of polarity or differential axon branch growth in cultured hippocampal neurons

31 March 2020

1 reference

A change in the selective translocation of the Kinesin-1 motor domain marks the initial specification of the axon

31 March 2020

1 reference

Axon formation: a molecular model for the generation of neuronal polarity

31 March 2020

1 reference

Experimental observations on the development of polarity by hippocampal neurons in culture

31 March 2020

1 reference

PIP3 is involved in neuronal polarization and axon formation.

31 March 2020

1 reference

Differentiated neurons retain the capacity to generate axons from dendrites

31 March 2020

1 reference

Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans.

31 March 2020

1 reference

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.

31 March 2020

1 reference

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

31 March 2020

1 reference

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

31 March 2020

1 reference

UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation

31 March 2020

1 reference

Molecular control of cortical dendrite development

31 March 2020

1 reference

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans

31 March 2020

1 reference

Wnt signals and frizzled activity orient anterior-posterior axon outgrowth in C. elegans

31 March 2020

1 reference

The Wnt signaling pathway in development and disease

31 March 2020

1 reference

Noncanonical Wnt signaling and neural polarity

31 March 2020

1 reference

Rho GTPases in cell biology

31 March 2020

1 reference

Trk receptors: roles in neuronal signal transduction

31 March 2020

1 reference

Asymmetric membrane ganglioside sialidase activity specifies axonal fate.

31 March 2020

1 reference

Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity

31 March 2020

1 reference

The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity

31 March 2020

1 reference

Transport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity

31 March 2020

1 reference

Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

31 March 2020

1 reference

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

31 March 2020

1 reference

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

31 March 2020

1 reference

Localization of the G protein betagamma complex in living cells during chemotaxis

31 March 2020

1 reference

Spatial sensing in fibroblasts mediated by 3' phosphoinositides

31 March 2020

1 reference

Chemotaxis: signalling the way forward

31 March 2020

1 reference

Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass

31 March 2020

1 reference

Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons

31 March 2020

1 reference

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

31 March 2020

1 reference

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

31 March 2020

1 reference

GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.

31 March 2020

1 reference

Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway

31 March 2020

1 reference

Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3beta) independently of Akt/PKB serine phosphorylation.

31 March 2020

1 reference

Requirement of dendritic Akt degradation by the ubiquitin-proteasome system for neuronal polarity

31 March 2020

1 reference

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

31 March 2020

1 reference

A selective role for phosphatidylinositol 3,4,5-trisphosphate in the Gi-dependent activation of platelet Rap1B.

31 March 2020

1 reference

Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

31 March 2020

1 reference

Prediction and validation of the distinct dynamics of transient and sustained ERK activation

31 March 2020

1 reference

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

31 March 2020

1 reference

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

31 March 2020

1 reference

Ras proteins: different signals from different locations

31 March 2020

1 reference

R-Ras controls axon specification upstream of glycogen synthase kinase-3beta through integrin-linked kinase

31 March 2020

1 reference

Raf functions downstream of Ras1 in the Sevenless signal transduction pathway

31 March 2020

1 reference

Phosphatidylinositol-3-OH kinase as a direct target of Ras

31 March 2020

1 reference

Mammalian Ras interacts directly with the serine/threonine kinase Raf

31 March 2020

1 reference

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

31 March 2020

1 reference

Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance

31 March 2020

1 reference

Slow axonal transport and the genesis of neuronal morphology

31 March 2020

1 reference

The role of local actin instability in axon formation

31 March 2020

1 reference

A critical role for a Rho-associated kinase, p160ROCK, in determining axon outgrowth in mammalian CNS neurons

31 March 2020

1 reference

The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth

31 March 2020

1 reference

Evidence for the involvement of Tiam1 in axon formation

31 March 2020

1 reference

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

31 March 2020

1 reference

Cell migration: integrating signals from front to back

31 March 2020

1 reference

The role of the Rho GTPases in neuronal development

31 March 2020

1 reference

Different roles for RhoA during neurite initiation, elongation, and regeneration in PC12 cells

31 March 2020

1 reference

Lysophosphatidic acid-induced neurite retraction in PC12 cells: control by phosphoinositide-Ca2+ signaling and Rho

31 March 2020

1 reference

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

31 March 2020

1 reference

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

31 March 2020

1 reference

The myotonic dystrophy kinase-related Cdc42-binding kinase is involved in the regulation of neurite outgrowth in PC12 cells

31 March 2020

1 reference

Essential role of neural Wiskott-Aldrich syndrome protein in neurite extension in PC12 cells and rat hippocampal primary culture cells

31 March 2020

1 reference

IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth

31 March 2020

1 reference

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

31 March 2020

1 reference

Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1

31 March 2020

1 reference

The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18

31 March 2020

1 reference

Asymmetric cell division in C. elegans: cortical polarity and spindle positioning

31 March 2020

1 reference

Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity

31 March 2020

1 reference

Baz, Par-6 and aPKC are not required for axon or dendrite specification in Drosophila.

31 March 2020

1 reference

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

31 March 2020

1 reference

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

31 March 2020

1 reference

Rho Family GTPases Bind to Phosphoinositide Kinases

31 March 2020

1 reference

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

31 March 2020

1 reference

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

31 March 2020

1 reference

APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity

31 March 2020

1 reference

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis

31 March 2020

1 reference

Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity

31 March 2020

1 reference

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

31 March 2020

1 reference

aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity

31 March 2020

1 reference

Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity

31 March 2020

1 reference

The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC.

31 March 2020

1 reference

Mammalian SAD kinases are required for neuronal polarization

31 March 2020

1 reference

Role of CRMP-2 in neuronal polarity.

31 March 2020

1 reference

Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

31 March 2020

1 reference

Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes

31 March 2020

1 reference

CRMP-2 induces axons in cultured hippocampal neurons

31 March 2020

1 reference

CRMP-2 binds to tubulin heterodimers to promote microtubule assembly

31 March 2020

1 reference

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

31 March 2020

1 reference

Numb antagonizes Notch signaling to specify sibling neuron cell fates

31 March 2020

1 reference

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

31 March 2020

1 reference

Numb is an endocytic protein

31 March 2020

1 reference

CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth

31 March 2020

1 reference

CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation

31 March 2020

1 reference

p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.

31 March 2020

1 reference

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

31 March 2020

1 reference

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

31 March 2020

1 reference

GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons.

31 March 2020

1 reference

Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease

31 March 2020

1 reference

Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones

31 March 2020

1 reference

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

31 March 2020

1 reference

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

31 March 2020

1 reference

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

31 March 2020

1 reference

Tau domains, phosphorylation, and interactions with microtubules.

31 March 2020

1 reference

NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC

31 March 2020

1 reference

Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes

31 March 2020

1 reference

Microtubules and neuronal polarity: lessons from mitosis

31 March 2020

1 reference

Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth

31 March 2020

1 reference

Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta

31 March 2020

1 reference

The Golgi apparatus and the centrosome are localized to the sites of newly emerging axons in cerebellar granule neurons in vitro

31 March 2020

1 reference

Organization of cytoskeletal elements and organelles preceding growth cone emergence from an identified neuron in situ

31 March 2020

1 reference

Centrosome localization determines neuronal polarity.

31 March 2020

1 reference

Polarization and orientation of retinal ganglion cells in vivo

31 March 2020

1 reference

Molecular motors and mechanisms of directional transport in neurons

31 March 2020

1 reference

A novel brain ATPase with properties expected for the fast axonal transport motor

31 March 2020

1 reference

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

31 March 2020

1 reference

Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide

31 March 2020

1 reference

Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head

31 March 2020

1 reference

Tubulin and CRMP-2 complex is transported via Kinesin-1

31 March 2020

1 reference

Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.

31 March 2020

1 reference

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

31 March 2020

1 reference

Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

31 March 2020

1 reference

Regulatory machinery of UNC-33 Ce-CRMP localization in neurites during neuronal development in Caenorhabditis elegans

31 March 2020

1 reference

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

31 March 2020

1 reference

Shootin1: A protein involved in the organization of an asymmetric signal for neuronal polarization

31 March 2020

1 reference

Neuronal polarity in CNS development

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRN2056

1 reference

Dimensions Publication ID

16 August 2017

1042279431

0 references

1 reference