Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases. (Q36836612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17541420%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

review article

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title

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases (English)

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31 December 2019

author

Philippe E Van den Steen

2

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31 December 2019

Ghislain Opdenakker

4

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31 December 2019

author name string

Jialiang Hu

1

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31 December 2019

Qing-Xiang A Sang

3

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31 December 2019

publication date

1 June 2007

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Nature Reviews Drug Discovery

31 December 2019

published in

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31 December 2019

volume

6

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31 December 2019

issue

6

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31 December 2019

page(s)

480-498

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A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains

31 December 2019

cites work

1 reference

Matrix metalloproteinase inhibitors: a review on pharmacophore mapping and (Q)SARs results

21 January 2018

1 reference

Urokinase-type plasminogen activator potentiates lipopolysaccharide-induced neutrophil activation

21 January 2018

1 reference

Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation

21 January 2018

1 reference

Resistance of collagenase-2 (matrix metalloproteinase-8)-deficient mice to TNF-induced lethal hepatitis

21 January 2018

1 reference

Matrix metalloproteinase-9 deficiency impairs cellular infiltration and bronchial hyperresponsiveness during allergen-induced airway inflammation

21 January 2018

1 reference

Matrix metalloproteinase-9-mediated dendritic cell recruitment into the airways is a critical step in a mouse model of asthma

21 January 2018

1 reference

Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation

21 January 2018

1 reference

Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium

21 January 2018

1 reference

Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin

21 January 2018

1 reference

The role of metalloelastase in immune complex-induced acute lung injury.

21 January 2018

1 reference

Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis

21 January 2018

1 reference

Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis

21 January 2018

1 reference

Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice

21 January 2018

1 reference

Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye

21 January 2018

1 reference

Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological diseases

21 January 2018

1 reference

New functions for the matrix metalloproteinases in cancer progression

21 January 2018

1 reference

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

31 March 2020

1 reference

Strategies for MMP inhibition in cancer: innovations for the post-trial era.

31 March 2020

1 reference

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family

31 March 2020

1 reference

Structural Characterization of the Catalytic Active Site in the Latent and Active Natural Gelatinase B from Human Neutrophils

31 March 2020

1 reference

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)

31 March 2020

1 reference

31 March 2020

Inflammation and cancer

1 reference

Cytokines and proteases in invasive processes: molecular similarities between inflammation and cancer.

31 March 2020

1 reference

The countercurrent principle in invasion and metastasis of cancer cells. Recent insights on the roles of chemokines.

31 March 2020

1 reference

Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand

31 March 2020

1 reference

Stromal matrix metalloproteinase-9 regulates the vascular architecture in neuroblastoma by promoting pericyte recruitment

31 March 2020

1 reference

Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system.

31 March 2020

1 reference

Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against the metalloproteinase gelatinase B (MMP-9).

31 March 2020

1 reference

The molecular basis of leukocytosis

31 March 2020

1 reference

Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells

31 March 2020

1 reference

Matrix metalloproteinases as modulators of inflammation and innate immunity

31 March 2020

1 reference

Gelatinase B/MMP-9 and neutrophil collagenase/MMP-8 process the chemokines human GCP-2/CXCL6, ENA-78/CXCL5 and mouse GCP-2/LIX and modulate their physiological activities.

31 March 2020

1 reference

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

31 March 2020

1 reference

Design and therapeutic application of matrix metalloproteinase inhibitors

31 March 2020

1 reference

Inhibitors of gelatinase B/matrix metalloproteinase-9 activity comparison of a peptidomimetic and polyhistidine with single-chain derivatives of a neutralizing monoclonal antibody

31 March 2020

1 reference

Novel functions of TIMPs in cell signaling

31 March 2020

1 reference

Tumour microenvironment - opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy.

31 March 2020

1 reference

Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases

31 March 2020

1 reference

Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design

31 March 2020

1 reference

Crystal structures of MMPs in complex with physiological and pharmacological inhibitors

31 March 2020

1 reference

Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

31 March 2020

1 reference

Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor

31 March 2020

1 reference

Design and synthesis of cyclic inhibitors of matrix metalloproteinases and TNF-alpha production

31 March 2020

1 reference

Simulation of evolution-selected propeptide by high-throughput selection of a peptidomimetic inhibitor on a capillary DNA sequencer platform.

31 March 2020

1 reference

Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits

31 March 2020

1 reference

Design and synthesis of phosphinamide-based hydroxamic acids as inhibitors of matrix metalloproteinases

31 March 2020

1 reference

Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase-inhibitor

31 March 2020

1 reference

The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases

31 March 2020

1 reference

Design and synthesis of novel inhibitors of gelatinase B.

31 March 2020

1 reference

X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor. comparison with the latent and active forms of the enzyme

31 March 2020

1 reference

Design, synthesis, and evaluation of a mechanism-based inhibitor for gelatinase A.

31 March 2020

1 reference

Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries

31 March 2020

1 reference

Tumor targeting with a selective gelatinase inhibitor

31 March 2020

1 reference

Chemically modified tetracyclines as inhibitors of matrix metalloproteinases

31 March 2020

1 reference

The gelatinase inhibitory activity of tetracyclines and chemically modified tetracycline analogues as measured by a novel microtiter assay for inhibitors.

31 March 2020

1 reference

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

31 March 2020

1 reference

Metalloproteinases in biology and pathology of the nervous system.

31 March 2020

1 reference

The immunopathogenesis of sepsis

31 March 2020

1 reference

The pathophysiology and treatment of sepsis

31 March 2020

1 reference

Toll-like receptors: how they work and what they do.

31 March 2020

1 reference

Gelatinase B deficiency protects against endotoxin shock

31 March 2020

1 reference

Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice

31 March 2020

1 reference

Regulation by C5a of neutrophil activation during sepsis

31 March 2020

1 reference

Targeting neutrophil collagenase/matrix metalloproteinase-8 and gelatinase B/matrix metalloproteinase-9 with a peptidomimetic inhibitor protects against endotoxin shock

31 March 2020

1 reference

Inhibition of lethal endotoxin shock with an L-pyridylalanine containing metalloproteinase inhibitor selected by high-throughput screening of a new peptide library

31 March 2020

1 reference

Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis

31 March 2020

1 reference

Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein.

31 March 2020

1 reference

Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.

31 March 2020

1 reference

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Gelatinase B/matrix metalloproteinase-9 cleaves interferon-beta and is a target for immunotherapy

31 March 2020

1 reference

Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases

31 March 2020

1 reference

Suppression of experimental allergic encephalomyelitis in the Lewis rat by the matrix metalloproteinase inhibitor Ro31-9790

31 March 2020

1 reference

Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine

31 March 2020

1 reference

Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis

31 March 2020

1 reference

Inhibition of autoimmune encephalomyelitis by a tetracycline.

31 March 2020

1 reference

An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization.

31 March 2020

1 reference

Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan

31 March 2020

1 reference

Cleavage of denatured natural collagen type II by neutrophil gelatinase B reveals enzyme specificity, post-translational modifications in the substrate, and the formation of remnant epitopes in rheumatoid arthritis

31 March 2020

1 reference

Generation of glycosylated remnant epitopes from human collagen type II by gelatinase B.

31 March 2020

1 reference

Inhibition of cartilage and bone destruction in adjuvant arthritis in the rat by a matrix metalloproteinase inhibitor

31 March 2020

1 reference

Anti-arthritic activity of hydroxamic acid-based pseudopeptide inhibitors of matrix metalloproteinases and TNF alpha processing

31 March 2020

1 reference

Preclinical antiarthritic activity of matrix metalloproteinase inhibitors

31 March 2020

1 reference

Identification and characterization of 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a novel dual tumor necrosis factor-alpha-converting enzyme/matrix metalloprotease inhibitor for the treatment o

31 March 2020

1 reference

The immune response in atherosclerosis: a double-edged sword

31 March 2020

1 reference

What has been learned about the cardiovascular effects of matrix metalloproteinases from mouse models?

31 March 2020

1 reference

Matrix metalloproteinases in coronary artery disease: clinical and therapeutic implications and pathological significance

31 March 2020

1 reference

Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus

31 March 2020

1 reference

The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo

31 March 2020

1 reference

Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

31 March 2020

1 reference

Matrix metalloproteinases and free radicals in cerebral ischemia

31 March 2020

1 reference

Role of matrix metalloproteinases in delayed cortical responses after stroke

31 March 2020

1 reference

Targeted disruption of the matrix metalloproteinase-9 gene impairs smooth muscle cell migration and geometrical arterial remodeling.

31 March 2020

1 reference

Matrix metalloproteinase-9 is necessary for the regulation of smooth muscle cell replication and migration after arterial injury

31 March 2020

1 reference

Tissue inhibitor of matrix metalloproteinases-1 impairs arterial neointima formation after vascular injury in mice

31 March 2020

1 reference

Vascular remodeling and protease inhibition--bench to bedside

31 March 2020

1 reference

New frontiers in cardiology: drug-eluting stents: Part II.

31 March 2020

1 reference

Accelerated neointima formation after vascular injury in mice with stromelysin-3 (MMP-11) gene inactivation

31 March 2020

1 reference

Persistence of atherosclerotic plaque but reduced aneurysm formation in mice with stromelysin-1 (MMP-3) gene inactivation

31 March 2020

1 reference

Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growth

31 March 2020

1 reference

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

31 March 2020

1 reference

Targeted deletion or pharmacological inhibition of MMP-2 prevents cardiac rupture after myocardial infarction in mice

31 March 2020

1 reference

Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action

31 March 2020

1 reference

Matrix metalloproteinases (MMPs) in oral diseases.

31 March 2020

1 reference

Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation.

31 March 2020

1 reference

The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis

31 March 2020

1 reference

A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats

31 March 2020

1 reference

Inhibition of alveolar bone loss by matrix metalloproteinase inhibitors in experimental periodontal disease.

31 March 2020

1 reference

Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice

31 March 2020

1 reference

Elastin fragments drive disease progression in a murine model of emphysema

31 March 2020

1 reference

Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release

31 March 2020

1 reference

The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo.

31 March 2020

1 reference

Matrix Metalloproteinases Inhibition Attenuates Tobacco Smoke-Induced Emphysema in Guinea Pigs

31 March 2020

1 reference

Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency

31 March 2020

1 reference

Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines

31 March 2020

1 reference

The involvement of matrix metalloproteinases in basement membrane injury in a murine model of acute allergic airway inflammation.

31 March 2020

1 reference

Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma

31 March 2020

1 reference

A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor

31 March 2020

1 reference

Inhibition of bleomycin-induced pulmonary fibrosis in mice by the matrix metalloproteinase inhibitor batimastat

31 March 2020

1 reference

Matrix metalloproteinases promote inflammation and fibrosis in asbestos-induced lung injury in mice

31 March 2020

1 reference

Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans

31 March 2020

1 reference

Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice

31 March 2020

1 reference

Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

31 March 2020

1 reference

Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy

31 March 2020

1 reference

MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs.

31 March 2020

1 reference

The influence of transforming growth factor beta 1 on the expression of genes coding for matrix metalloproteinases and tissue inhibitors of metalloproteinases during regeneration from cerulein-induced pancreatitis

31 March 2020

1 reference

In vivo activation of gelatinase B/MMP-9 by trypsin in acute pancreatitis is a permissive factor in streptozotocin-induced diabetes

31 March 2020

1 reference

Gelatinase B is diabetogenic in acute and chronic pancreatitis by cleaving insulin.

31 March 2020

1 reference

Matrix metalloproteinase (MMP)-8 and MMP-9 in cerebrospinal fluid during bacterial meningitis: association with blood-brain barrier damage and neurological sequelae

31 March 2020

1 reference

Inhibition of matrix metalloproteinases and tumour necrosis factor alpha converting enzyme as adjuvant therapy in pneumococcal meningitis

31 March 2020

1 reference

Matrix metalloproteinase-9 deficiency impairs host defense mechanisms against Streptococcus pneumoniae in a mouse model of bacterial meningitis

31 March 2020

1 reference

Metalloproteinases: mediators of pathology and regeneration in the CNS.

31 March 2020

1 reference

The ADAMTS metalloproteinases

31 March 2020

1 reference

Neutralizing antibodies in gene-defective hosts

31 March 2020

1 reference

X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design

31 March 2020

1 reference

Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor

31 March 2020

1 reference

Matrix metalloproteinase inhibitors in the treatment of cancer

31 March 2020

1 reference

Phase I trial of Marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer

31 March 2020

1 reference

Malonyl alpha-mercaptoketones and alpha-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors

31 March 2020

1 reference

Inhibition of obliterative airway disease development in murine tracheal allografts by matrix metalloproteinase-9 deficiency

31 March 2020

1 reference

Role of stromelysin 1 and gelatinase B in experimental acute lung injury

31 March 2020

1 reference

Matrilysin expression and function in airway epithelium

31 March 2020

1 reference

Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling

31 March 2020

1 reference

Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation

31 March 2020

1 reference

Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 (MT1-MMP).

31 March 2020

1 reference

Membrane-type 1 matrix metalloproteinase is required for normal alveolar development.

31 March 2020

1 reference

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

31 March 2020

1 reference

Enhanced early vascular permeability in gelatinase B (MMP-9)-deficient mice: putative contribution of COX-1-derived PGE2 of macrophage origin

31 March 2020

1 reference

Gelatinase B/matrix metalloproteinase-9 contributes to cellular infiltration in a murine model of zymosan peritonitis

31 March 2020

1 reference

Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.

31 March 2020

1 reference

Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis

31 March 2020

1 reference

Enamelysin (matrix metalloproteinase 20)-deficient mice display an amelogenesis imperfecta phenotype.

31 March 2020

1 reference

Formation of the dentino-enamel interface in enamelysin (MMP-20)-deficient mouse incisors

31 March 2020

1 reference

The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis

31 March 2020

1 reference

Susceptibility of stromelysin 1-deficient mice to collagen-induced arthritis and cartilage destruction

31 March 2020

1 reference

Matrix metalloproteinase-9 (gelatinase B) deficiency leads to increased severity of Staphylococcus aureus-triggered septic arthritis

31 March 2020

1 reference

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

31 March 2020

1 reference

Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation

31 March 2020

1 reference

Medial collateral ligament healing in macrophage metalloelastase (MMP-12)-deficient mice

31 March 2020

1 reference

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

31 March 2020

1 reference

The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone.

31 March 2020

1 reference

Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury

31 March 2020

1 reference

Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice

31 March 2020

1 reference

Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice.

31 March 2020

1 reference

Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94.

31 March 2020

1 reference

Role of matrix metalloproteinase-9 in a mouse model for amyotrophic lateral sclerosis

31 March 2020

1 reference

An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

31 March 2020

1 reference

The expression of matrix metalloproteinase-12 by oligodendrocytes regulates their maturation and morphological differentiation.

31 March 2020

1 reference

Absence of mechanical allodynia and Abeta-fiber sprouting after sciatic nerve injury in mice lacking membrane-type 5 matrix metalloproteinase

31 March 2020

1 reference

Different roles for matrix metalloproteinase-2 and matrix metalloproteinase-9 in the pathogenesis of cardiac allograft rejection.

31 March 2020

1 reference

Delayed inflammation-associated corneal neovascularization in MMP-2-deficient mice.

31 March 2020

1 reference

Reduced retinal angiogenesis in MMP-2-deficient mice

31 March 2020

1 reference

Reduced choroidal neovascular membrane formation in matrix metalloproteinase-2-deficient mice.

31 March 2020

1 reference

Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases

31 March 2020

1 reference

MMP-2 and MMP-9 synergize in promoting choroidal neovascularization

31 March 2020

1 reference

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

31 March 2020

1 reference

Myocardial ischemia induces interleukin-6 and tissue factor production in patients with coronary artery disease: a dobutamine stress echocardiography study

31 March 2020

1 reference

Retinal vascular development and pathologic retinal angiogenesis are not impaired in matrix metalloproteinase-2 deficient mice

31 March 2020

1 reference

Effect of MMP-2 deficiency on atherosclerotic lesion formation in apoE-deficient mice

31 March 2020

1 reference

Time-dependent changes in myocardial structure following discrete injury in mice deficient of matrix metalloproteinase-3.

31 March 2020

1 reference

Corneal neovascularization after excimer keratectomy wounds in matrilysin-deficient mice

31 March 2020

1 reference

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

31 March 2020

1 reference

Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization

31 March 2020

1 reference

Role of matrix metalloproteinase-9 in endothelial apoptosis in chronic heart failure in mice

31 March 2020

1 reference

Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction.

31 March 2020

1 reference

Matrix metalloproteinase-9 is required for adequate angiogenic revascularization of ischemic tissues: potential role in capillary branching.

31 March 2020

1 reference

Earlier Onset of Tumoral Angiogenesis in Matrix Metalloproteinase-19–Deficient Mice

31 March 2020

1 reference

Matrix metalloproteinase 9 facilitates collagen remodeling and angiogenesis for vascular constructs

31 March 2020

1 reference

Matrix metalloproteinase-9 modulation by resident arterial cells is responsible for injury-induced accelerated atherosclerotic plaque development in apolipoprotein E-deficient mice

31 March 2020

1 reference

MMP-12 has a role in abdominal aortic aneurysms in mice.

31 March 2020

1 reference

Matrix metalloproteinase deficiencies affect contact hypersensitivity: stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response

31 March 2020

1 reference

Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice

31 March 2020

1 reference

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

31 March 2020

1 reference

Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption

31 March 2020

1 reference

Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption

31 March 2020

1 reference

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.

31 March 2020

1 reference

Surfactant protein-D regulates soluble CD14 through matrix metalloproteinase-12

31 March 2020

1 reference

Hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor and erythropoietin in the absence of matrix metalloproteinase-9

31 March 2020

1 reference

Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid

31 March 2020

1 reference

Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin

31 March 2020

1 reference

Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice

31 March 2020

1 reference

Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient mice

31 March 2020

1 reference

The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent.

31 March 2020

1 reference

Cold preservation of isolated sinusoidal endothelial cells in MMP 9 knockout mice: effect on morphology and platelet adhesion

31 March 2020

1 reference

Stromelysin-3 is a potent negative regulator of adipogenesis participating to cancer cell-adipocyte interaction/crosstalk at the tumor invasive front

31 March 2020

1 reference

Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice

31 March 2020

1 reference