Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43) (Q36873601)

16 August 2017

Aberrant assembly of RNA recognition motif 1 links to pathogenic conversion of TAR DNA-binding protein of 43 kDa (TDP-43) (English)

1 reference

RNA recognition motif domain

16 August 2017

1 reference

Makoto Urushitani

17

0 references

Takanori Kigawa

object named as

Takanori Kigawa

10

0 references

Shigeyuki Yokoyama

object named as

Shigeyuki Yokoyama

12

0 references

Yutaka Muto

11

object named as

Yutaka Muto

1 reference

16 August 2017

Akemi Shodai

1

1 reference

16 August 2017

Toshifumi Morimura

2

1 reference

16 August 2017

Akemi Ido

3

1 reference

16 August 2017

Tsukasa Uchida

4

1 reference

16 August 2017

Takashi Ayaki

5

1 reference

16 August 2017

Rina Takahashi

6

1 reference

16 August 2017

Soichiro Kitazawa

7

1 reference

16 August 2017

Sakura Suzuki

8

1 reference

16 August 2017

Mikako Shirouzu

9

1 reference

16 August 2017

Ryosuke Takahashi

13

1 reference

16 August 2017

Ryo Kitahara

14

1 reference

16 August 2017

Hidefumi Ito

15

1 reference

16 August 2017

Noriko Fujiwara

16

1 reference

16 August 2017

language of work or name

English

0 references

publication date

4 April 2013

1 reference

Journal of Biological Chemistry

16 August 2017

1 reference

16 August 2017

288

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16 August 2017

21

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16 August 2017

14886-14905

1 reference

describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3663511/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress

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Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43.

29 September 2017

1 reference

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How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?

29 September 2017

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Redox Regulation of Protein Function via Cysteine S-Nitrosylation and Its Relevance to Neurodegenerative Diseases

29 September 2017

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Redox signalling directly regulates TDP-43 via cysteine oxidation and disulphide cross-linking

29 September 2017

1 reference

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Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways

29 September 2017

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TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies

29 September 2017

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A "two-hit" hypothesis for inclusion formation by carboxyl-terminal fragments of TDP-43 protein linked to RNA depletion and impaired microtubule-dependent transport

29 September 2017

1 reference

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A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions

29 September 2017

1 reference

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RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS.

29 September 2017

1 reference

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Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

29 September 2017

1 reference

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Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

29 September 2017

1 reference

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TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling

29 September 2017

1 reference

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Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

29 September 2017

1 reference

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Neurotoxic effects of TDP-43 overexpression in C. elegans

29 September 2017

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29 September 2017

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Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis

29 September 2017

1 reference

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Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.

29 September 2017

1 reference

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Structural insights into TDP-43 in nucleic-acid binding and domain interactions

29 September 2017

1 reference

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Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells

29 September 2017

1 reference

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Structural determinants of the cellular localization and shuttling of TDP-43.

29 September 2017

1 reference

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Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

29 September 2017

1 reference

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Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

29 September 2017

1 reference

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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

29 September 2017

1 reference

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Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation

29 September 2017

1 reference

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Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking.

29 September 2017

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Hot spots in prion protein for pathogenic conversion

29 September 2017

1 reference

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

29 September 2017

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

29 September 2017

1 reference

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Protein misfolding, functional amyloid, and human disease

29 September 2017

1 reference

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Probing conformational fluctuation of proteins by pressure perturbation

29 September 2017

1 reference

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Modulation of prion protein structure by pressure and temperature.

29 September 2017

1 reference

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Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9

29 September 2017

1 reference

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Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43)

29 September 2017

1 reference

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Cellular model of TAR DNA-binding protein 43 (TDP-43) aggregation based on its C-terminal Gln/Asn-rich region

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Cognitive decline typical of frontotemporal lobar degeneration in transgenic mice expressing the 25-kDa C-terminal fragment of TDP-43.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Oxidative modification to cysteine sulfonic acid of Cys111 in human copper-zinc superoxide dismutase

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Redox modifications of protein-thiols: emerging roles in cell signaling

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of exon 9: a functional link with disease penetrance

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Novel method for evaluation of the oligomeric structure of membrane proteins

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3663511

Evolutionally Conserved Intermediates Between Ubiquitin and NEDD8

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.451849

Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23558684

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23558684

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.451849

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

23558684

1 reference