Generation of a panel of related human scFv antibodies with high affinities for human CEA. (Q36891667)

16 August 2017

title

Generation of a panel of related human scFv antibodies with high affinities for human CEA. (English)

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16 August 2017

Osbourn JK

1

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16 August 2017

Field A

2

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16 August 2017

Wilton J

3

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16 August 2017

Derbyshire E

4

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16 August 2017

Earnshaw JC

5

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16 August 2017

Jones PT

6

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16 August 2017

Allen D

7

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16 August 2017

McCafferty J

8

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16 August 2017

publication date

1 September 1996

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Immunotechnology : an international journal of immunological engineering

16 August 2017

published in

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16 August 2017

volume

2

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16 August 2017

issue

3

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16 August 2017

page(s)

181-196

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Medical applications of single-chain antibodies

16 August 2017

cites work

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Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

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Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen

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By-passing immunization: building high affinity human antibodies by chain shuffling

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Selection of phage antibodies by binding affinity

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Comparative protein modelling by satisfaction of spatial restraints

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Selection and rapid purification of murine antibody fragments that bind a transition-state analog by phage display

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By-passing immunization. Human antibodies from V-gene libraries displayed on phage

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Direct clone characterization from plaques and colonies by the polymerase chain reaction.

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Making antibody fragments using phage display libraries

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Canonical structures for the hypervariable regions of immunoglobulins

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Affinity maturation of a high-affinity human monoclonal antibody against the third hypervariable loop of human immunodeficiency virus: use of phage display to improve affinity and broaden strain reactivity

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Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection

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Antibody-antigen interactions: new structures and new conformational changes

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Structural analysis of antibody specificity. Detailed comparison of five Fab'-steroid complexes

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Isolation of high affinity human antibodies directly from large synthetic repertoires.

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Clinical evaluation of tumor targeting with a high-affinity, anticarcinoembryonic-antigen-specific, murine monoclonal antibody, MN-14

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The effect of tumor CEA content and tumor size on tissue uptake of indium 111-labeled anti-CEA monoclonal antibody

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In vivo tumor targeting of a recombinant single-chain antigen-binding protein

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Antibody framework residues affecting the conformation of the hypervariable loops

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7 January 2021

10.1016/S1380-2933(96)00046-2

Identifiers

DOI

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16 August 2017

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