Cancer and ageing: convergent and divergent mechanisms (Q36918634)

17 August 2017

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title

Cancer and ageing: convergent and divergent mechanisms (English)

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17 August 2017

Manuel Serrano

1

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Maria A Blasco

object named as

Maria A Blasco

series ordinal

2

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publication date

1 September 2007

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Nature Reviews Molecular Cell Biology

17 August 2017

published in

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17 August 2017

volume

8

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17 August 2017

issue

9

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17 August 2017

page(s)

715-722

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INK4a/ARF: a multifunctional tumor suppressor locus

17 August 2017

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The first molecular details of ALT in human tumor cells

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis

31 March 2020

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ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

31 March 2020

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Association between telomere length in blood and mortality in people aged 60 years or older

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High-throughput telomere length quantification by FISH and its application to human population studies

31 March 2020

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Telomere length regulation during postnatal development and ageing in Mus spretus

31 March 2020

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Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice.

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Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC.

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Putting the stress on senescence

31 March 2020

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

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Ink4a/Arf expression is a biomarker of aging

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p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

31 March 2020

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

31 March 2020

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

31 March 2020

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Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

31 March 2020

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p16INK4a induces an age-dependent decline in islet regenerative potential

31 March 2020

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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

31 March 2020

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Hematopoietic stem cell quiescence maintained by p21cip1/waf1

31 March 2020

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Complicating the role of p53 in aging.

31 March 2020

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The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

31 March 2020

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Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

31 March 2020

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Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

31 March 2020

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Genomic instability in laminopathy-based premature aging

31 March 2020

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Telomerase regulation and stem cell behaviour

31 March 2020

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Increased p53 activity does not accelerate telomere-driven ageing

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRM2242

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Dimensions Publication ID

17 August 2017

1033612140

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