An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1. (Q36951875)

17 August 2017

An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1. (English)

1 reference

17 August 2017

Brandon Scott Carpenter

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27146892%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Matthew R McFarlane

10

1 reference

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5 June 2020

Benjamin L Allen

13

1 reference

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5 June 2020

Scott Barolo

15

1 reference

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5 June 2020

14

Andrew P McMahon

1 reference

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5 June 2020

author name string

David S Lorberbaum

1

1 reference

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5 June 2020

Andrea I Ramos

2

1 reference

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5 June 2020

Kevin A Peterson

3

1 reference

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5 June 2020

David S Parker

5

1 reference

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5 June 2020

Sandip De

6

1 reference

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5 June 2020

Lauren E Hillers

7

1 reference

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5 June 2020

Victoria M Blake

8

1 reference

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5 June 2020

Yuichi Nishi

9

1 reference

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5 June 2020

Ason Cy Chiang

11

1 reference

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5 June 2020

Judith A Kassis

12

1 reference

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5 June 2020

language of work or name

English

0 references

publication date

5 May 2016

1 reference

17 August 2017

1 reference

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5 June 2020

volume

5

1 reference

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Suboptimization of developmental enhancers

5 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Krüppel Expression Levels Are Maintained through Compensatory Evolution of Shadow Enhancers

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

New insights for Drosophila GAGA factor in larvae

9 September 2017

1 reference

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Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples

9 September 2017

1 reference

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Determination and inference of eukaryotic transcription factor sequence specificity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex

9 September 2017

1 reference

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Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish

9 September 2017

1 reference

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A common set of DNA regulatory elements shapes Drosophila appendages

9 September 2017

1 reference

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A dynamic population of stromal cells contributes to the follicle stem cell niche in the Drosophila ovary

9 September 2017

1 reference

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Architectural and functional diversity of polycomb group response elements in Drosophila

9 September 2017

1 reference

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Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

The mechanisms of Hedgehog signalling and its roles in development and disease

9 September 2017

1 reference

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Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Polycomb group response elements in Drosophila and vertebrates

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

9 September 2017

1 reference

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A GAL4-driver line resource for Drosophila neurobiology

9 September 2017

1 reference

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A model of spatially restricted transcription in opposing gradients of activators and repressors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Widespread plasticity in CTCF occupancy linked to DNA methylation

9 September 2017

1 reference

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Hh signalling is essential for somatic stem cell maintenance in the Drosophila testis niche

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Topological domains in mammalian genomes identified by analysis of chromatin interactions

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Ancestral and conserved cis-regulatory architectures in developmental control genes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Craniofacial divergence and ongoing adaptation via the hedgehog pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Rapid evolutionary rewiring of a structurally constrained eye enhancer

9 September 2017

1 reference

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The cis-regulatory logic of Hedgehog gradient responses: key roles for gli binding affinity, competition, and cooperativity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Dynamic reprogramming of chromatin accessibility during Drosophila embryo development

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Shadow enhancers foster robustness of Drosophila gastrulation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

9 September 2017

1 reference

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Phenotypic robustness conferred by apparently redundant transcriptional enhancers

9 September 2017

1 reference

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Hedgehog beyond medulloblastoma and basal cell carcinoma

9 September 2017

1 reference

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Fast and accurate long-read alignment with Burrows-Wheeler transform

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

9 September 2017

1 reference

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Unlocking the secrets of the genome

9 September 2017

1 reference

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Basal cell carcinomas: attack of the hedgehog

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Promoter elements associated with RNA Pol II stalling in the Drosophila embryo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

The rise and fall of Hox gene clusters

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Transgenic Wnt/TCF pathway reporters: all you need is Lef?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

GAGA protein: a multi-faceted transcription factor

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

GenePalette: a universal software tool for genome sequence visualization and analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Regulation of pattern formation in the Drosophila hindgut by wg, hh, dpp, and en.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Mouse patched1 controls body size determination and limb patterning.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Dual roles for patched in sequestering and transducing Hedgehog

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Transcription factor TFIID recognizes DNA sequences downstream of the TATA element in the Hsp70 heat shock gene

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Genome-wide association of Yorkie with chromatin and chromatin-remodeling complexes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Structural rules and complex regulatory circuitry constrain expression of a Notch- and EGFR-regulated eye enhancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Low affinity binding site clusters confer hox specificity and regulatory robustness.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Hedgehog targets in theDrosophilaembryo and the mechanisms that generate tissue-specific outputs of Hedgehog signaling

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Hedgehog acts as a somatic stem cell factor in the Drosophila ovary

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Genome-scale functional characterization of Drosophila developmental enhancers in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887206

Genetic analysis of hedgehog signalling in the Drosophila embryo

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27146892

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.7554/ELIFE.13550

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27146892%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27146892%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

27146892

1 reference