A role for TREX components in the release of spliced mRNA from nuclear speckle domains (Q37222258)

19 August 2017

A role for TREX components in the release of spliced mRNA from nuclear speckle domains (English)

1 reference

19 August 2017

Kobina Dufu

2

1 reference

19 August 2017

Haixin Lei

series ordinal

3

1 reference

19 August 2017

Robin Reed

series ordinal

4

1 reference

19 August 2017

Anusha P. Dias

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

11 August 2024

language of work or name

English

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publication date

19 October 2010

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full work available at URL

19 August 2017

https://www.nature.com/articles/ncomms1103.pdf

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Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20981025/pdf/?tool=EBI

11 August 2024

file format

Portable Document Format

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20981025/?tool=EBI

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

https://europepmc.org/articles/PMC3793428

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

https://europepmc.org/articles/PMC3793428?pdf=render

11 August 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

https://doi.org/10.1038/ncomms1103

11 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20981025

11 August 2024

published in

Nature Communications

1 reference

19 August 2017

1

1 reference

19 August 2017

97

1 reference

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3793428/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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9 September 2017

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9 September 2017

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9 September 2017

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Pre-mRNA processing reaches back to transcription and ahead to translation

9 September 2017

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Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci

9 September 2017

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9 September 2017

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Association between active genes occurs at nuclear speckles and is modulated by chromatin environment

9 September 2017

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Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

9 September 2017

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Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

9 September 2017

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Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome

9 September 2017

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Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY.

9 September 2017

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mRNA journey to the cytoplasm: attire required

9 September 2017

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Functional integration of transcriptional and RNA processing machineries

9 September 2017

1 reference

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Splicing promotes rapid and efficient mRNA export in mammalian cells

9 September 2017

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Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP

9 September 2017

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Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains

9 September 2017

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Exporting RNA from the nucleus to the cytoplasm

9 September 2017

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The exosome and RNA quality control in the nucleus

9 September 2017

1 reference

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Human mRNA export machinery recruited to the 5' end of mRNA

9 September 2017

1 reference

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A link between transcription and mRNP quality in Saccharomyces cerevisiae.

9 September 2017

1 reference

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Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Molecular anatomy of a speckle

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Regulating gene expression through RNA nuclear retention

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Recruitment of the human TREX complex to mRNA during splicing

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Quality control of messenger ribonucleoprotein particles in the nucleus and at the pore

9 September 2017

1 reference

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Formation of export-competent mRNP: escaping nuclear destruction

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

TREX, SR proteins and export of mRNA.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Poly(A)+ RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells

9 September 2017

1 reference

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Nuclear speckles: a model for nuclear organelles

9 September 2017

1 reference

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Coupling transcription, splicing and mRNA export

9 September 2017

1 reference

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Early formation of mRNP: license for export or quality control?

9 September 2017

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An extensive network of coupling among gene expression machines

9 September 2017

1 reference

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A conserved mRNA export machinery coupled to pre-mRNA splicing

9 September 2017

1 reference

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Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly

9 September 2017

1 reference

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Protein dynamics: implications for nuclear architecture and gene expression.

9 September 2017

1 reference

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Prespliceosomal assembly on microinjected precursor mRNA takes place in nuclear speckles

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Nuclear pre-mRNA compartmentalization: trafficking of released transcripts to splicing factor reservoirs

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Splicing is required for rapid and efficient mRNA export in metazoans

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Processing of endogenous pre-mRNAs in association with SC-35 domains is gene specific

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Intranuclear distribution of poly(A) RNA determined by electron microscope in situ hybridization

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

In vivo analysis of the stability and transport of nuclear poly(A)+ RNA.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Discrete nuclear domains of poly(A) RNA and their relationship to the functional organization of the nucleus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Evidence that all SC-35 domains contain mRNAs and that transcripts can be structurally constrained within these domains

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Induction of p21 mRNA synthesis after short-wavelength UV light visualized in individual cells by RNA FISH.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Inefficient processing impairs release of RNA from the site of transcription

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Gene associations: true romance or chance meeting in a nuclear neighborhood?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

The dynamics of pre-mRNAs and poly(A)+ RNA at speckles in living cells revealed by iFRAP studies

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Splicing factor SF3b as a target of the antitumor natural product pladienolide

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Identity elements used in export of mRNAs

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3793428

Higher level organization of individual gene transcription and RNA splicing

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20981025

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Single-molecule imaging and quantification of mRNAs in a living cell]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20981025

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS1103

1 reference

19 August 2017

0 references

1 reference

19 August 2017

1 reference