P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice. (Q37290383)

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scientific article published on 05 May 2009

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English	P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice.	scientific article published on 05 May 2009

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scholarly article

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27 January 2020

P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice (English)

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Europe PubMed Central

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27 January 2020

4

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27 January 2020

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Wei Chen

1

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27 January 2020

Xin-Bo Zhou

2

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27 January 2020

Hong-Ying Liu

3

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27 January 2020

Li-Li Wang

5

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27 January 2020

Song Li

6

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27 January 2020

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5 May 2009

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27 January 2020

British Journal of Pharmacology

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27 January 2020

157

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27 January 2020

5

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27 January 2020

724-735

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27 January 2020

The PPARalpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats

1 reference

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Fine tuning of PPAR ligands for type 2 diabetes and metabolic syndrome.

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New therapeutic options for the metabolic syndrome: what's next?

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6 September 2017

Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future

1 reference

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6 September 2017

Be fit or be sick: peroxisome proliferator-activated receptors are down the road

1 reference

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6 September 2017

The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity

2 references

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6 September 2017

https://pubmed.ncbi.nlm.nih.gov/19422369

12 December 2020

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Metabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR)

1 reference

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AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats

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Interaction between free fatty acids and glucose metabolism

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Insulin signalling and the regulation of glucose and lipid metabolism

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6 September 2017

Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones

1 reference

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Peroxisome proliferator-activated receptors, coactivators, and downstream targets

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Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

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6 September 2017

C333H, a novel PPARalpha/gamma dual agonist, has beneficial effects on insulin resistance and lipid metabolism.

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14 September 2017

N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents

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Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-Ll cells.

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26 June 2018

A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats

1 reference

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Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.

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26 June 2018

Peroxisome proliferator-activated receptor delta-agonist, GW501516, ameliorates insulin resistance, improves dyslipidaemia in monosodium L-glutamate metabolic syndrome mice

1 reference

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3 September 2018

Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination

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3 September 2018

The dual PPARalpha/gamma agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats.

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Rosiglitazone improves insulin sensitivity and glucose tolerance in subjects with impaired glucose tolerance.

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Combination therapy with PPARgamma and PPARalpha agonists increases glucose-stimulated insulin secretion in db/db mice

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The effect of exercise training on adiponectin receptor expression in KKAy obese/diabetic mice

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General Survey of Diabetic Features of Yellow KK Mice

1 reference

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inferred from PubMed ID database lookup

Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19422369

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2009.00231.X

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27 January 2020

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27 January 2020

PubMed publication ID

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27 January 2020

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